| Parabilis Medicines, Inc. | 28.9M | US$792M | 6.9% |
| Rhythm Pharmaceuticals, Inc. | 6.67M | US$740M | 6.4% |
| Vaxcyte, Inc. | 11.5M | US$667M | 5.8% |
| Sionna Therapeutics, Inc. | 9.91M | US$436M | 3.8% |
| Tyra Biosciences, Inc. | 12.2M | US$390M | 3.4% |
| Edgewise Therapeutics, Inc. | 8.39M | US$341M | 3.0% |
| Hemab Therapeutics Holdings, Inc. | 7.81M | US$287M | 2.5% |
| Septerna, Inc. | 7M | US$234M | 2.0% |
| Bicara Therapeutics Inc. | 7.26M | US$215M | 1.9% |
| Mineralys Therapeutics, Inc. | 7.69M | US$208M | 1.8% |
| Disc Medicine, Inc. | 2.45M | US$179M | 1.6% |
| Spyglass Pharma, Inc. | 8.02M | US$179M | 1.6% |
| Artiva Biotherapeutics, Inc. | 18M | US$174M | 1.5% |
| Janux Therapeutics, Inc. | 11.2M | US$172M | 1.5% |
| Taysha Gene Therapies, Inc. | 23.6M | US$160M | 1.4% |
| Biocryst Pharmaceuticals, Inc. | 15.8M | US$158M | 1.4% |
| Nuvalent, Inc. | 1.25M | US$154M | 1.3% |
| Abivax Sa | 1.13M | US$151M | 1.3% |
| Oruka Therapeutics, Inc. | 1.55M | US$148M | 1.3% |
| Climb Bio, Inc. | 11.3M | US$147M | 1.3% |
| Solid Biosciences Inc. | 12M | US$120M | 1.0% |
| Zai Lab Ltd. | 5.74M | US$109M | 0.95% |
| Ars Pharmaceuticals, Inc. | 10.9M | US$87M | 0.76% |
| Xencor, Inc. | 5.27M | US$84.9M | 0.74% |
| Jade Biosciences, Inc. | 3.67M | US$81.6M | 0.71% |
| Intellia Therapeutics, Inc. | 4.53M | US$76.6M | 0.67% |
| Lb Pharmaceuticals Inc | 2.21M | US$71.7M | 0.62% |
| Definium Therapeutics, Inc. | 1.5M | US$70.6M | 0.61% |
| Aclaris Therapeutics, Inc. | 12.7M | US$67.3M | 0.58% |
| 4d Molecular Therapeutics, Inc. | 5.05M | US$67.2M | 0.58% |
| Sana Biotechnology, Inc. | 18.8M | US$65.4M | 0.57% |
| Damora Therapeutics, Inc. | 2.4M | US$62.4M | 0.54% |
| Monopar Therapeutics Inc. | 667K | US$61.8M | 0.54% |
| Acumen Pharmaceuticals, Inc. | 21M | US$56.1M | 0.49% |
| Geron Corporation | 42.8M | US$54.8M | 0.48% |
| Rezolute, Inc. | 9.45M | US$49.1M | 0.43% |
| Evommune, Inc. | 3.49M | US$46.4M | 0.40% |
| Vor Biopharma Inc. | 2.4M | US$44.2M | 0.38% |
| Century Therapeutics, Inc. | 17.8M | US$43.5M | 0.38% |
| Aktis Oncology, Inc. | 1.31M | US$42.4M | 0.37% |
| Bioage Labs, Inc. | 1.67M | US$41M | 0.36% |
| C4 Therapeutics, Inc. | 8M | US$37.4M | 0.32% |
| Mirum Pharmaceuticals, Inc. | 319K | US$37.3M | 0.32% |
| Capricor Therapeutics, Inc. | 1.51M | US$36.3M | 0.32% |
| Pepgen Inc. | 20.1M | US$36.1M | 0.31% |
| Prelude Therapeutics Incorporated | 6.48M | US$34.5M | 0.30% |
| Nkarta, Inc. | 10.8M | US$30.6M | 0.27% |
| Q32 Bio Inc. | 2.33M | US$29.7M | 0.26% |
| Anteris Technologies Global Corp. | 3M | US$29.6M | 0.26% |
| Editas Medicine, Inc. | 8.89M | US$28.8M | 0.25% |
| Ovid Therapeutics Inc. | 10.5M | US$28.2M | 0.25% |
| Assembly Biosciences, Inc. | 1.02M | US$28M | 0.24% |
| Alx Oncology Holdings Inc. | 13M | US$26.9M | 0.23% |
| Benitec Biopharma Inc. | 1.85M | US$24.8M | 0.22% |
| Lenz Therapeutics, Inc. | 4.18M | US$23.7M | 0.21% |
| Lexeo Therapeutics, Inc. | 5M | US$23.3M | 0.20% |
| Acrivon Therapeutics, Inc. | 12.2M | US$21.8M | 0.19% |
| Altimmune, Inc. | 6.5M | US$19.8M | 0.17% |
| Karyopharm Therapeutics Inc. | 1.92M | US$18.7M | 0.16% |
| Bright Minds Biosciences Inc. | 265K | US$18.6M | 0.16% |
| Avalo Therapeutics, Inc. | 1M | US$18.5M | 0.16% |
| Onkure Therapeutics, Inc. | 4M | US$18.2M | 0.16% |
| Sensei Biotherapeutics, Inc. | 722K | US$18.1M | 0.16% |
| Aura Biosciences, Inc. | 2.5M | US$17.8M | 0.15% |
| Sab Biotherapeutics, Inc. | 4.4M | US$17.2M | 0.15% |
| Seaport Therapeutics, Inc. | 700K | US$15.2M | 0.13% |
| Palisade Bio, Inc. | 7.12M | US$14.9M | 0.13% |
| Helix Acquisition Corp. Iii | 1.25M | US$13.3M | 0.12% |
| Waystar Holding Corp. | 529K | US$10.9M | 0.09% |
| Equillium, Inc. | 3.1M | US$9.91M | 0.09% |
| Macrogenics, Inc. | 1.86M | US$8.61M | 0.07% |
| Perceptive Capital Solutions Corp | 750K | US$8.16M | 0.07% |
| Adicet Bio, Inc. | 933K | US$8.06M | 0.07% |
| Corvus Pharmaceuticals, Inc. | 450K | US$6.72M | 0.06% |
| Rani Therapeutics Holdings, Inc. | 8.5M | US$6.46M | 0.06% |
| Jatt Ii Acquisition Corp | 500K | US$5.68M | 0.05% |
| Amanat Acquisition Corp | 375K | US$3.81M | 0.03% |
| Werewolf Therapeutics, Inc. | 2.39M | US$859K | <0.01% |
| Palatin Technologies, Inc. | 62,124 | US$670K | <0.01% |
| Design Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Maplight Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Olema Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Praxis Precision Medicines, Inc. | 0 | US$0 | 0.00% |
| Relmada Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Genedx Holdings Corp. | 0 | US$0 | 0.00% |
| Travere Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Dianthus Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Fulcrum Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Grail, Inc. | 0 | US$0 | 0.00% |
| Hinge Health, Inc. | 0 | US$0 | 0.00% |
| Inspire Medical Systems, Inc. | 0 | US$0 | 0.00% |
| Sarepta Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Sutro Biopharma, Inc. | 0 | US$0 | 0.00% |
| Spyre Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Ascendis Pharma A/s | 0 | US$0 | 0.00% |
| Atrium Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Contineum Therapeutics, Inc. | 0 | US$0 | 0.00% |