| United Therapeutics Corporation | 52,989 | US$28.7M | 3.6% |
| Revolution Medicines, Inc. | 139K | US$26.1M | 3.3% |
| Abivax Sa | 164K | US$21.6M | 2.7% |
| Cogent Biosciences, Inc. | 494K | US$19.1M | 2.4% |
| Biomarin Pharmaceutical Inc. | 313K | US$17.9M | 2.3% |
| Viking Therapeutics, Inc. | 442K | US$17.2M | 2.2% |
| Edgewise Therapeutics, Inc. | 272K | US$11.1M | 1.4% |
| Kodiak Sciences Inc | 218K | US$8.5M | 1.1% |
| 4d Molecular Therapeutics, Inc. | 571K | US$7.6M | 0.96% |
| Arcus Biosciences, Inc. | 224K | US$6.9M | 0.87% |
| Johnson & Johnson | 22,000 | US$5.59M | 0.71% |
| Novo Nordisk A/s Class B | 100K | US$4.81M | 0.61% |
| Corvus Pharmaceuticals, Inc. | 295K | US$4.4M | 0.56% |
| Relay Therapeutics, Inc. | 231K | US$4.32M | 0.55% |
| Zymeworks Inc. | 142K | US$3.72M | 0.47% |
| Bioage Labs, Inc. | 146K | US$3.59M | 0.45% |
| Taysha Gene Therapies, Inc. | 523K | US$3.56M | 0.45% |
| Nurix Therapeutics, Inc. | 122K | US$2.95M | 0.37% |
| Corbus Pharmaceuticals Holdings, Inc. | 301K | US$2.83M | 0.36% |
| Indivior Pharmaceuticals, Inc. | 67,512 | US$2.77M | 0.35% |
| Inventiva Sa | 741K | US$2.73M | 0.34% |
| Oruka Therapeutics, Inc. | 27,799 | US$2.65M | 0.33% |
| Vaxcyte, Inc. | 45,071 | US$2.62M | 0.33% |
| Relmada Therapeutics, Inc. | 361K | US$2.5M | 0.32% |
| Vera Therapeutics, Inc. | 57,608 | US$2.47M | 0.31% |
| Contineum Therapeutics, Inc. | 120K | US$1.96M | 0.25% |
| Monte Rosa Therapeutics, Inc. | 78,391 | US$1.9M | 0.24% |
| Viridian Therapeutics, Inc. | 100K | US$1.84M | 0.23% |
| Macrogenics, Inc. | 374K | US$1.73M | 0.22% |
| Spruce Biosciences, Inc. | 30,000 | US$1.62M | 0.20% |
| Ardelyx, Inc. | 303K | US$1.55M | 0.20% |
| Cue Biopharma, Inc. | 48,369 | US$1.53M | 0.19% |
| Mineralys Therapeutics, Inc. | 56,347 | US$1.52M | 0.19% |
| Voyager Therapeutics, Inc. | 414K | US$1.45M | 0.18% |
| Unicycive Therapeutics, Inc. | 304K | US$1.42M | 0.18% |
| Phathom Pharmaceuticals, Inc. | 130K | US$1.41M | 0.18% |
| Spyre Therapeutics, Inc. | 15,000 | US$1.33M | 0.17% |
| Cybin, Inc. | 200K | US$1.32M | 0.17% |
| Equillium, Inc. | 400K | US$1.28M | 0.16% |
| Xeris Biopharma Holdings, Inc. | 133K | US$1.05M | 0.13% |
| Harmony Biosciences Holdings, Inc. | 26,864 | US$978K | 0.12% |
| Cartesian Therapeutics, Inc. | 87,057 | US$907K | 0.11% |
| Rigel Pharmaceuticals, Inc. | 22,816 | US$893K | 0.11% |
| Summit Therapeutics Inc. | 60,000 | US$874K | 0.11% |
| Precigen, Inc. | 135K | US$771K | 0.10% |
| Definium Therapeutics, Inc. | 15,451 | US$727K | 0.09% |
| Pelthos Therapeutics Inc. | 24,773 | US$700K | 0.09% |
| Pepgen Inc. | 373K | US$672K | 0.08% |
| Enliven Therapeutics, Inc. | 10,000 | US$508K | 0.06% |
| Connect Biopharma Holdings Limited | 197K | US$469K | 0.06% |
| Larimar Therapeutics, Inc. | 147K | US$447K | 0.06% |
| Cellectar Biosciences, Inc. | 138K | US$385K | 0.05% |
| Foghorn Therapeutics Inc. | 66,908 | US$327K | 0.04% |
| Aytu Biopharma, Inc. | 149K | US$319K | 0.04% |
| Ocugen, Inc. | 200K | US$306K | 0.04% |
| Heron Therapeutics, Inc. | 459K | US$196K | 0.02% |
| Talphera, Inc. | 154K | US$158K | 0.02% |
| Annexon, Inc. | 27,516 | US$157K | 0.02% |
| Monopar Therapeutics Inc. | 1,630 | US$151K | 0.02% |
| Lakeland Industries, Inc. | 14,108 | US$151K | 0.02% |
| Upstream Bio, Inc. | 19,093 | US$132K | 0.02% |
| Meiragtx Holdings Plc | 8,368 | US$113K | 0.01% |
| Jatt Ii Acquisition Corp | 9,021 | US$102K | 0.01% |
| Kailera Therapeutics, Inc. | 3,621 | US$79,771 | 0.01% |
| Mannkind Corporation | 16,003 | US$68,173 | <0.01% |
| Ars Pharmaceuticals, Inc. | 4,860 | US$38,929 | <0.01% |
| Aprea Therapeutics, Inc. | 44,907 | US$36,029 | <0.01% |
| Tvardi Therapeutics, Inc. | 16,607 | US$31,553 | <0.01% |
| Nextcure, Inc. | 7,742 | US$12,387 | <0.01% |
| Abbvie Inc. | 0 | US$0 | 0.00% |
| Atrium Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Bridgebio Pharma, Inc. | 0 | US$0 | 0.00% |
| Capricor Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Celcuity Inc. | 0 | US$0 | 0.00% |
| Climb Bio, Inc. | 0 | US$0 | 0.00% |
| Corcept Therapeutics Incorporated | 0 | US$0 | 0.00% |
| Dianthus Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Eli Lilly And Company | 0 | US$0 | 0.00% |
| Enanta Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Eupraxia Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Eyepoint, Inc. | 0 | US$0 | 0.00% |
| Incyte Corporation | 0 | US$0 | 0.00% |
| Inovio Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Lipocine Inc. | 0 | US$0 | 0.00% |
| Maze Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Passage Bio, Inc. | 0 | US$0 | 0.00% |
| Puretech Health Plc | 0 | US$0 | 0.00% |
| Replimune Group, Inc. | 0 | US$0 | 0.00% |
| Rocket Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Septerna, Inc. | 0 | US$0 | 0.00% |
| Shattuck Labs, Inc. | 0 | US$0 | 0.00% |
| Tarsus Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Tenax Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Terns Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Tg Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Trevi Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Ultragenyx Pharmaceutical Inc. | 0 | US$0 | 0.00% |
| Vertex Pharmaceuticals Incorporated | 0 | US$0 | 0.00% |
| Vistagen Therapeutics, Inc. | 0 | US$0 | 0.00% |