Stock listing
NASDAQ:UPB Upstream Bio, Inc. Stock
Home listing (NASDAQ) of Upstream Bio, Inc.
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Share price · NASDAQ:UPB
$3.41 USD +0.14 (+4.3%)
Close on Oct 30, 2026
- Day range
- $3.15 – $3.43 USDOct 30, 2026
- Volume
- 946,122 sharesOct 30, 2026
- Market cap
- $186.8M USDAt the close on Oct 30, 2026 · price × 54.77M shares outstanding
- 52-week range
- $2.68 – $33.68 USDLowest and highest trades, Oct 31, 2025 – Oct 30, 2026
- Traded on an average day
- $4.13M USDMedian day 750,250 shares · last 3 months, Jul 30, 2026 – Oct 30, 2026
Prices by listing
| Listing | Last | Change | Volume | Open | High | Low | Previous close | Price from |
|---|---|---|---|---|---|---|---|---|
| NASDAQ:UPB · Home | $3.41 USD | +0.14 (+4.3%) | 946,122 | $3.26 | $3.425 | $3.15 | $3.27 | Close on Oct 30, 2026 |
Daily closes
Last 3 months, Jul 30, 2026 – Oct 30, 2026 · NASDAQ:UPB · USD, adjusted for splits
| Day | Close | Change | % | Open | High | Low | Volume |
|---|---|---|---|---|---|---|---|
| $3.41 | +0.14 | +4.3% | $3.26 | $3.425 | $3.15 | 946,122 | |
| $3.27 | +0.29 | +9.7% | $3.00 | $3.32 | $2.97 | 1,178,779 | |
| $2.98 | +0.19 | +6.8% | $2.78 | $2.99 | $2.68 | 1,323,091 | |
| $2.79 | +0.04 | +1.5% | $2.76 | $2.935 | $2.68 | 1,179,620 | |
| $2.75 | +0.01 | +0.4% | $2.75 | $2.97 | $2.72 | 983,842 | |
| $2.74 | -0.25 | -8.4% | $2.95 | $2.96 | $2.695 | 1,051,200 | |
| $2.99 | +0.19 | +6.8% | $2.77 | $2.99 | $2.70 | 1,450,000 | |
| $2.80 | -0.02 | -0.7% | $2.83 | $2.975 | $2.765 | 1,410,500 | |
| $2.82 | +0.02 | +0.7% | $2.79 | $3.09 | $2.78 | 1,676,000 | |
| $2.80 | +0.04 | +1.4% | $2.76 | $3.07 | $2.75 | 1,603,700 | |
| $2.76 | -0.61 | -18.1% | $3.39 | $3.39 | $2.74 | 1,836,400 | |
| $3.37 | -0.05 | -1.5% | $3.44 | $3.555 | $3.285 | 1,285,300 | |
| $3.42 | -0.13 | -3.7% | $3.475 | $3.60 | $3.29 | 1,572,500 | |
| $3.55 | -0.62 | -14.9% | $4.14 | $4.155 | $3.52 | 1,037,400 | |
| $4.17 | -0.53 | -11.3% | $4.68 | $4.72 | $4.12 | 848,400 | |
| $4.70 | +0.15 | +3.3% | $4.54 | $4.76 | $4.51 | 1,187,800 | |
| $4.55 | -0.06 | -1.3% | $4.53 | $4.65 | $4.365 | 2,857,200 | |
| $4.61 | +0.02 | +0.4% | $4.55 | $4.72 | $4.50 | 908,400 | |
| $4.59 | -0.26 | -5.4% | $4.84 | $4.865 | $4.53 | 1,062,300 | |
| $4.85 | -0.19 | -3.8% | $5.07 | $5.10 | $4.665 | 1,010,600 | |
| $5.04 | 0.00 | 0.0% | $5.12 | $5.21 | $4.86 | 956,500 | |
| $5.04 | -0.23 | -4.4% | $5.25 | $5.345 | $4.98 | 832,400 | |
| $5.27 | +0.08 | +1.5% | $5.23 | $5.455 | $5.145 | 851,200 | |
| $5.19 | -0.11 | -2.1% | $5.28 | $5.305 | $4.99 | 784,200 | |
| $5.30 | -0.06 | -1.1% | $5.34 | $5.385 | $5.12 | 615,400 | |
| $5.36 | +0.19 | +3.7% | $5.20 | $5.39 | $5.07 | 429,200 | |
| $5.17 | -0.02 | -0.4% | $5.19 | $5.20 | $5.045 | 566,600 | |
| $5.19 | -0.30 | -5.5% | $5.48 | $5.49 | $4.985 | 553,000 | |
| $5.49 | +0.125 | +2.3% | $5.44 | $5.56 | $5.38 | 360,400 | |
| $5.365 | +0.025 | +0.5% | $5.42 | $5.44 | $5.27 | 364,000 | |
| $5.34 | +0.03 | +0.6% | $5.32 | $5.41 | $5.21 | 1,001,000 | |
| $5.31 | -0.02 | -0.4% | $5.44 | $5.48 | $5.235 | 533,900 | |
| $5.33 | -0.15 | -2.7% | $5.49 | $5.54 | $5.27 | 497,200 | |
| $5.48 | -0.33 | -5.7% | $5.81 | $5.81 | $5.455 | 421,300 | |
| $5.81 | +0.08 | +1.4% | $5.75 | $5.87 | $5.70 | 491,000 | |
| $5.73 | -0.02 | -0.3% | $5.84 | $5.84 | $5.65 | 501,300 | |
| $5.75 | -0.21 | -3.5% | $5.86 | $5.86 | $5.67 | 562,400 | |
| $5.96 | -0.23 | -3.7% | $6.14 | $6.20 | $5.77 | 726,200 | |
| $6.19 | +0.18 | +3.0% | $6.01 | $6.21 | $5.77 | 949,700 | |
| $6.01 | -0.07 | -1.2% | $6.00 | $6.23 | $5.965 | 642,900 | |
| $6.08 | -0.40 | -6.2% | $6.49 | $6.49 | $5.77 | 1,351,800 | |
| $6.48 | -0.07 | -1.1% | $6.62 | $6.98 | $6.41 | 515,400 | |
| $6.55 | -0.07 | -1.1% | $6.58 | $6.72 | $6.50 | 476,500 | |
| $6.62 | -0.07 | -1.0% | $6.64 | $6.77 | $6.44 | 895,000 | |
| $6.69 | -0.10 | -1.5% | $6.71 | $6.79 | $6.60 | 445,500 | |
| $6.79 | -0.34 | -4.8% | $7.11 | $7.14 | $6.78 | 335,100 | |
| $7.13 | -0.05 | -0.7% | $7.18 | $7.31 | $6.90 | 432,900 | |
| $7.18 | +0.57 | +8.6% | $6.68 | $7.18 | $6.55 | 554,420 | |
| $6.61 | -0.36 | -5.2% | $7.00 | $7.11 | $6.46 | 538,545 | |
| $6.97 | +0.12 | +1.8% | $6.91 | $7.006 | $6.85 | 434,200 | |
| $6.85 | -0.665 | -8.8% | $7.48 | $7.555 | $6.745 | 592,900 | |
| $7.515 | +0.665 | +9.7% | $7.04 | $7.53 | $6.91 | 574,100 | |
| $6.85 | -0.29 | -4.1% | $7.28 | $7.435 | $6.73 | 461,600 | |
| $7.14 | +0.07 | +1.0% | $7.02 | $7.19 | $6.86 | 852,400 | |
| $7.07 | +0.16 | +2.3% | $6.95 | $7.14 | $6.80 | 688,200 | |
| $6.91 | 0.00 | 0.0% | $7.02 | $7.04 | $6.87 | 378,800 | |
| $6.91 | -0.18 | -2.5% | $7.00 | $7.25 | $6.84 | 635,100 | |
| $7.09 | -0.35 | -4.7% | $7.48 | $7.70 | $7.01 | 628,055 | |
| $7.44 | +0.19 | +2.6% | $7.32 | $7.62 | $7.20 | 869,591 | |
| $7.25 | +0.38 | +5.5% | $6.94 | $7.26 | $6.89 | 621,800 | |
| $6.87 | +0.13 | +1.9% | $6.75 | $7.166 | $6.66 | 427,200 | |
| $6.74 | -0.05 | -0.7% | $6.77 | $6.88 | $6.58 | 917,300 | |
| $6.79 | +0.37 | +5.8% | $6.40 | $6.915 | $6.40 | 1,362,500 | |
| $6.42 | +0.11 | +1.7% | $6.31 | $6.43 | $6.175 | 774,300 | |
| $6.31 | -0.26 | -4.0% | $6.58 | $6.688 | $6.29 | 297,700 | |
| $6.57 | +0.16 | +2.5% | $6.35 | $6.665 | $6.29 | 320,600 |
- Ticker
- NASDAQ:UPB
- Asset type
- Stock
- Sector
- Health care
- Industry
- Biotechnology
- Exchange
- NASDAQ
- Currency
- USD
What changed lately
Latest news release · Aug 11, 2026
Upstream Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Progress
Latest deck · Sep 8, 2026
Investor Presentation (September 2026)
Investor deck · 26 slides
Latest news
Upstream Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Progress
Aug 11, 2026
Closed $7.09 (-4.7%) on Aug 11, 2026
Upstream Bio Presents New Responder Analyses Demonstrating Clinically Meaningful Improvements in CRSwNP in Significant Majority of Participants Treated with Verekitug in the Phase 2 VIBRANT Trial at EAACI 2026
Jun 14, 2026
Closed $6.10 (0.0%) on Jun 15, 2026
Upstream Bio to Showcase Additional Efficacy Data from the Phase 2 VIBRANT Trial of Verekitug in CRSwNP in Oral Session at EAACI 2026
Jun 8, 2026
Closed $6.45 (-8.5%) on Jun 8, 2026
Upstream Bio to Present at the Goldman Sachs 47th Annual Global Healthcare Conference
Jun 3, 2026
Closed $7.63 (+5.2%) on Jun 3, 2026
Upstream Bio Presents New Data from Phase 2 VIBRANT Trial of Verekitug Demonstrating Improvement in Asthma Symptom Control in Participants with CRSwNP and Comorbid Asthma at the ATS 2026 International Conference
May 18, 2026
Closed $8.51 (-6.4%) on May 18, 2026
Upstream Bio Reports First Quarter 2026 Financial Results and Recent Business Highlights
May 13, 2026
Closed $9.36 (+4.6%) on May 13, 2026
Upstream Bio to Present New Data from Phase 2 VIBRANT Trial of Verekitug at the ATS 2026 International Conference
Apr 17, 2026
Closed $9.99 (-1.1%) on Apr 17, 2026
Upstream Bio Highlights Phase 3 Development Strategy for Verekitug and Reports Fourth Quarter and Full Year 2025 Financial Results
Mar 26, 2026
Closed $9.79 (+3.4%) on Mar 26, 2026
Decks
Investor Presentation (September 2026)
Investor deck · 26 slides · Sep 8, 2026
Technical Presentation (September 2026)
Technical · 11 slides · September 2026
Technical Presentation (February 2026)
Technical · 19 slides · Feb 11, 2026
Technical Presentation (September 2025)
Technical · 25 slides · Sep 2, 2025
Upstream Bio, Inc. on 6ix
- Sector
- Health care
- Industry
- Biotechnology
- News releases
- 16 in the last 12 months · 37 in all · newest Aug 11, 2026 · oldest 2024
- Decks
- 6 decks · latest Sep 8, 2026
Where Upstream Bio, Inc. is listed
| Listing | Exchange | Country | Currency |
|---|---|---|---|
| NASDAQ:UPB · Home listing · This page | NASDAQ | United States | USD |
| BOATS:UPB | BOATS | United States | USD |
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