| Madrigal Pharmaceuticals, Inc. | 1.99M | US$1.07B | 9.1% |
| Argenx Se | 709K | US$658M | 5.6% |
| Ptc Therapeutics, Inc. | 7.75M | US$632M | 5.4% |
| Protagonist Therapeutics, Inc. | 5.06M | US$620M | 5.3% |
| Cg Oncology, Inc. | 8.51M | US$605M | 5.2% |
| Insmed Incorporated | 4.84M | US$516M | 4.4% |
| Tango Therapeutics, Inc. | 13.9M | US$435M | 3.7% |
| Spyre Therapeutics, Inc. | 4.25M | US$377M | 3.2% |
| Celcuity Inc. | 3.3M | US$346M | 3.0% |
| Erasca, Inc. | 17.9M | US$329M | 2.8% |
| Radnet, Inc. | 4.85M | US$299M | 2.6% |
| Oruka Therapeutics, Inc. | 3.14M | US$299M | 2.6% |
| Natera, Inc. | 1M | US$271M | 2.3% |
| Ultragenyx Pharmaceutical Inc. | 7.8M | US$260M | 2.2% |
| Irhythm Holdings, Inc. | 2.18M | US$260M | 2.2% |
| Cytokinetics, Incorporated | 2.86M | US$244M | 2.1% |
| Kailera Therapeutics, Inc. | 10.8M | US$237M | 2.0% |
| Establishment Labs Holdings Inc. | 2.66M | US$228M | 1.9% |
| Guardant Health, Inc. | 1.48M | US$222M | 1.9% |
| Neurocrine Biosciences, Inc. | 1.27M | US$214M | 1.8% |
| Tarsus Pharmaceuticals, Inc. | 3.36M | US$211M | 1.8% |
| Stoke Therapeutics, Inc. | 5.62M | US$184M | 1.6% |
| Acadia Pharmaceuticals Inc. | 7.14M | US$181M | 1.5% |
| Repligen Corporation | 1.24M | US$169M | 1.4% |
| Zai Lab Ltd. | 6.57M | US$125M | 1.1% |
| Immunovant, Inc. | 3.18M | US$122M | 1.0% |
| Xencor, Inc. | 6.78M | US$109M | 0.93% |
| Taysha Gene Therapies, Inc. | 13.6M | US$92.3M | 0.79% |
| Cogent Biosciences, Inc. | 2.31M | US$89.4M | 0.76% |
| Replimune Group, Inc. | 7.41M | US$82M | 0.70% |
| Castle Biosciences, Inc. | 2.78M | US$66.3M | 0.57% |
| Candel Therapeutics, Inc. | 6.42M | US$66.1M | 0.56% |
| Rocket Pharmaceuticals, Inc. | 17.7M | US$60.5M | 0.52% |
| Kodiak Sciences Inc | 1.49M | US$58M | 0.49% |
| Aktis Oncology, Inc. | 1.59M | US$51.3M | 0.44% |
| Axogen, Inc. | 1.01M | US$46.7M | 0.40% |
| Danaher Corporation | 230K | US$43.8M | 0.37% |
| Cullinan Therapeutics, Inc. | 2.36M | US$43.1M | 0.37% |
| Neurogene Inc. | 1.36M | US$42.8M | 0.37% |
| Hinge Health, Inc. | 500K | US$41.5M | 0.35% |
| Orchestra Biomed Holdings, Inc. | 9.56M | US$41.2M | 0.35% |
| Solid Biosciences Inc. | 3.89M | US$38.9M | 0.33% |
| Savara, Inc. | 5.95M | US$36.7M | 0.31% |
| Aquestive Therapeutics, Inc. | 7.43M | US$30.9M | 0.26% |
| Kymera Therapeutics, Inc. | 240K | US$27.5M | 0.23% |
| Verastem, Inc. | 6.64M | US$25.3M | 0.22% |
| Dianthus Therapeutics, Inc. | 248K | US$24.2M | 0.21% |
| Beta Bionics, Inc. | 1.5M | US$23.5M | 0.20% |
| Century Therapeutics, Inc. | 8.7M | US$21.3M | 0.18% |
| Evommune, Inc. | 1.5M | US$20M | 0.17% |
| Beam Therapeutics Inc. | 570K | US$19.6M | 0.17% |
| Definium Therapeutics, Inc. | 400K | US$18.8M | 0.16% |
| Ideaya Biosciences, Inc. | 370K | US$13.8M | 0.12% |
| Ataibeckley Inc. | 2M | US$10.5M | 0.09% |
| Milestone Pharmaceuticals Inc. | 7.83M | US$10.5M | 0.09% |
| Ocugen, Inc. | 6.67M | US$10.2M | 0.09% |
| Tenax Therapeutics, Inc. | 697K | US$10.1M | 0.09% |
| Heartflow, Inc. | 295K | US$8.66M | 0.07% |
| Perceptive Capital Solutions Corp | 743K | US$8.08M | 0.07% |
| Larimar Therapeutics, Inc. | 2.57M | US$7.83M | 0.07% |
| Lumexa Imaging Holdings, Inc. | 650K | US$7.33M | 0.06% |
| Allogene Therapeutics, Inc. | 3.25M | US$6.76M | 0.06% |
| Crescent Biopharma, Inc. | 373K | US$6.71M | 0.06% |
| 4d Molecular Therapeutics, Inc. | 476K | US$6.33M | 0.05% |
| Maze Therapeutics, Inc. | 212K | US$6.33M | 0.05% |
| Capricor Therapeutics, Inc. | 250K | US$6.02M | 0.05% |
| Kalaris Therapeutics, Inc. | 1.3M | US$5.29M | 0.05% |
| Abivax Sa | 26,400 | US$3.52M | 0.03% |
| Avalo Therapeutics, Inc. | 175K | US$3.23M | 0.03% |
| Medline Inc. | 70,000 | US$2.76M | 0.02% |
| Disc Medicine, Inc. | 30,000 | US$2.19M | 0.02% |
| Imagenebio, Inc. | 334K | US$1.97M | 0.02% |
| Exagen Inc. | 195K | US$907K | <0.01% |
| Stryker Corporation | 0 | US$0 | 0.00% |
| Waystar Holding Corp. | 0 | US$0 | 0.00% |
| Apellis Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Apogee Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Arrowhead Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Compass Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Crinetics Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Fulgent Genetics, Inc. | 0 | US$0 | 0.00% |
| Intuitive Surgical, Inc. | 0 | US$0 | 0.00% |
| Inventiva Sa | 0 | US$0 | 0.00% |
| Jade Biosciences, Inc. | 0 | US$0 | 0.00% |
| Omada Health, Inc. | 0 | US$0 | 0.00% |