Seikagaku CorporationTSE: 4548

Financial Results for the Fiscal Year 2024

· Issued by Seikagaku Corporation
Financial Results for the Fiscal Year 2024

(April 1, 2024 - March 31, 2025)

(TSE:4548)



  • FY2024 Results P3-7
    • Overview

    • Domestic Pharmaceuticals

    • Overseas Pharmaceuticals

    • Bulk Products / CDMO, Royalty, LAL Business

    • Trend in R&D Expenses

  • FY2025 Forecasts P8-12
  • Overview

  • Domestic Pharmaceuticals

  • Overseas Pharmaceuticals

  • Bulk Products / CDMO, Royalty, LAL Business

    • Research and Development P13-18


      • SI-6603 (Lumbar disc herniation)

      • Gel-One (Osteoarthritis of the knee and the hip)

      • SI-722(Interstitial cystitis and bladder pain syndrome)

      • SI-449 (Adhesion Barrier)

    • Other Topics P19-22
  • Status of Application for Approval of SI-6603 in the United

    States

  • Progress Against the Mid-Term Management Plan in Fiscal 2024

  • Basic Policy on Profit Distribution

< Cautionary Notes >

This material contains forward-looking statements regarding future management strategies or performance forecasts. These statements are based on judgments derived from information that is currently available to Seikagaku and are subject to risk and uncertainty. Actual results and developments may differ significantly from these forward-looking statements due to various factors.

Information about pharmaceutical products or medical devices (including products currently in development)





included in this material is not intended to constitute an advertisement or medical advice. 2

Contents

E x p l o r i n g t h e I n n o v a t i v e P r o m i s e o f G l y c o s c i e n c e



E x p l o r i n g t h e I n n o v a t i v e

FY2024 Results



P r o m i s e o f G l y c o s c i e n c e





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  • Net sales: Up 8.7% on increases in royalty income, and higher sales in the LAL business

  • Operating Income: Up 207.8% due to the revenue increase

  • Ordinary Income: Up 14.3%, below operating income growth because of recognition of foreign exchange loss

  • Net Income: Down 44.5% due to higher tax expenses

    Net Sales by Business Segment

    Overseas Sales Ratio

    (Millions of Yen)

    FY 2023

    Results

    FY 2024

    Results

    % of

    Change

    +8.7%

    Net Income

    36,213

    39,374

    Operating Income

    433

    1,333

    +207.8%

    Ordinary

    Income

    1,691

    1,933

    +14.3%

    Net Income

    2,186

    1,214

    -44.5%

    Net Income

    per Share

    ¥40.08

    ¥22.25

    ー

    +8.7%

    (Millions of Yen)

    FY 2023

    Other Performance

    FY 2023 FY 2024 % of



    10,059

9,804

12,100

11,919

36,213

3,083

39,374

39.7%

60.3%

Domestic Pharma

Overseas Pharma

Bulk Products / CDMO Royalty

LAL

38.0%

62.0%

11,860

2,598

3,192

FY 2024

Domestic Overseas

Indicators Change

699

R& D Expenses

(Millions of Yen)

Ratio of R& D expenses to sales

( excluding royalty income)

Exchange rate at end of period (US$1)

Ave. exchange rate during

the period (US$1 )

7,484 7,643 +2.1%

21.1% 20.8% -0.3pt

¥151.4 ¥149.5 -¥1.9

¥144.6 ¥152.6 +¥8.0

10,271

FY 2023 FY 2024

Domestic Overseas

*excluding royalty income





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FY2024 Results

Overview

E x p l o r i n g t h e I n n o v a t i v e P r o m i s e o f G l y c o s c i e n c e



FY2024 Results

Domestic Pharmaceuticals

  • Net sales down 1.5% year on year due to lower sales of ARTZ and the OPEGAN series



Sales Comparison

ARTZ(Joint-function improving agent)

E x p l o r i n g t h e I n n o v a t i v e P r o m i s e o f G l y c o s c i e n c e

(Millions of Yen)

-1.5%

  • Market share: Up on higher deliveries to medical institutions (Approx 83%*)

  • Seikagaku sales: Facilities maintenance for the purpose of production system expansion at the Company's plant was completed, and shipment volume increased year





    12,100 11,919

    FY 2023 FY 2024

    on year. However, the Company's sales declined year on year due to a

    decrease in unit prices reductions.



    OPEGAN series(Ophthalmic viscoelastic devices)

    • Market share: At the prior-year level because of higher deliveries to medical

      institutions and market growth (Approx 51%*)

    • Seikagaku sales: Down due to a decline in unit prices



      Other Products(Seikagaku sales)

    • Hernicore: Down due to shipment timing

    • MucoUp: Down due to the impact of an NHI reimbursement price change

    • JOYCLU: Up due to shipment timing

Continued to gather side effects reports and other information on JOYCLU and provide

safety-related information.





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*Source:Copyright © 2025 IQVIA. Calculated based on JPM April 2023 - March 2025 by SKK , Reprinted with permission