Stock listing
Tradegate:ISI Ionis Pharmaceuticals, Inc. Aktie
German listing (Tradegate) of Ionis Pharmaceuticals, Inc. · home listing NASDAQ:IONS
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Home listing price · NASDAQ:IONS
$43.96 USD +0.54 (+1.2%)
Close on Oct 27, 2026 · This listing has no price on 6ix; the price shown is the home listing's, NASDAQ:IONS
- Day range
- $43.03 – $44.05 USDOct 27, 2026
- Volume
- 2.32M sharesOct 27, 2026
- Market cap
- $7.31B USDAt the close on Oct 27, 2026 · price × 166.2M shares outstanding
- 52-week range
- $42.08 – $86.74 USDLowest and highest trades, Oct 28, 2025 – Oct 27, 2026
Prices by listing
| Listing | Last | Change | Volume | Open | High | Low | Previous close | Price from |
|---|---|---|---|---|---|---|---|---|
| NASDAQ:IONS · Home | $43.96 USD | +0.54 (+1.2%) | 2,321,891 | $43.23 | $44.05 | $43.03 | $43.42 | Close on Oct 27, 2026 |
| LSE:0JDI | $43.68 USD | +0.73 (+1.7%) | 205 | $42.85 | $44.00 | $42.85 | $42.95 | Close on Oct 27, 2026 |
| Frankfurt:ISI | €38.60 EUR | -0.26 (-0.7%) | — | €38.60 | €38.60 | €38.60 | €38.86 | Close on Oct 27, 2026 |
| Munich:ISI | €38.67 EUR | -0.78 (-2.0%) | — | €38.67 | €38.67 | €38.67 | €39.45 | Close on Oct 27, 2026 |
| Stuttgart:ISI | €39.31 EUR | +0.91 (+2.4%) | — | €38.81 | €39.40 | €38.61 | €38.40 | Close on Oct 27, 2026 |
Daily closes
Last 3 months, Jul 27, 2026 – Oct 27, 2026 · NASDAQ:IONS · USD, adjusted for splits
| Day | Close | Change | % | Open | High | Low | Volume |
|---|---|---|---|---|---|---|---|
| $43.96 | +0.54 | +1.2% | $43.23 | $44.05 | $43.03 | 2,321,891 | |
| $43.42 | +0.49 | +1.1% | $43.00 | $43.92 | $42.76 | 2,311,048 | |
| $42.93 | -0.98 | -2.2% | $43.80 | $43.80 | $42.58 | 3,013,738 | |
| $43.91 | -0.36 | -0.8% | $45.02 | $45.15 | $43.41 | 5,012,019 | |
| $44.27 | -1.13 | -2.5% | $45.55 | $45.76 | $44.26 | 2,269,836 | |
| $45.40 | +1.02 | +2.3% | $44.45 | $45.48 | $44.01 | 2,487,410 | |
| $44.38 | +1.44 | +3.4% | $43.33 | $44.54 | $43.00 | 3,098,987 | |
| $42.94 | -1.18 | -2.7% | $44.53 | $44.65 | $42.80 | 1,674,884 | |
| $44.12 | +1.42 | +3.3% | $43.58 | $44.71 | $43.42 | 2,484,999 | |
| $42.70 | +0.32 | +0.8% | $42.22 | $43.47 | $42.08 | 2,027,743 | |
| $42.38 | -1.29 | -3.0% | $43.55 | $43.58 | $42.36 | 2,978,032 | |
| $43.67 | -1.61 | -3.6% | $45.37 | $45.46 | $43.62 | 1,950,359 | |
| $45.28 | +1.98 | +4.6% | $43.21 | $45.72 | $43.12 | 4,862,320 | |
| $43.30 | -0.86 | -1.9% | $43.76 | $44.19 | $42.79 | 3,349,330 | |
| $44.16 | +0.16 | +0.4% | $43.75 | $44.26 | $43.53 | 2,943,620 | |
| $44.00 | +0.50 | +1.1% | $44.19 | $44.67 | $43.17 | 2,193,060 | |
| $43.50 | -0.04 | -0.1% | $43.75 | $43.96 | $42.63 | 2,871,832 | |
| $43.54 | -0.46 | -1.0% | $44.17 | $44.17 | $43.24 | 2,312,084 | |
| $44.00 | -0.65 | -1.5% | $44.63 | $45.95 | $43.96 | 2,030,329 | |
| $44.65 | -1.24 | -2.7% | $46.07 | $46.25 | $44.60 | 2,630,197 | |
| $45.89 | +0.32 | +0.7% | $45.53 | $46.46 | $45.39 | 3,885,842 | |
| $45.57 | +1.07 | +2.4% | $44.56 | $46.95 | $44.06 | 3,742,302 | |
| $44.50 | +0.69 | +1.6% | $44.25 | $45.28 | $43.62 | 6,202,420 | |
| $43.81 | -0.12 | -0.3% | $43.77 | $44.60 | $43.25 | 6,448,795 | |
| $43.93 | -1.82 | -4.0% | $46.23 | $46.41 | $43.01 | 3,535,786 | |
| $45.75 | +0.85 | +1.9% | $44.96 | $46.13 | $44.44 | 4,236,217 | |
| $44.90 | +0.46 | +1.0% | $44.95 | $45.25 | $44.20 | 4,521,358 | |
| $44.44 | -2.31 | -4.9% | $46.75 | $46.75 | $44.27 | 7,369,358 | |
| $46.75 | +1.91 | +4.3% | $46.68 | $47.42 | $45.75 | 4,079,573 | |
| $44.84 | -2.41 | -5.1% | $47.38 | $47.59 | $44.66 | 7,958,214 | |
| $47.25 | -4.19 | -8.1% | $51.37 | $51.37 | $46.72 | 6,812,465 | |
| $51.44 | -2.77 | -5.1% | $54.88 | $55.50 | $51.31 | 5,974,753 | |
| $54.21 | -1.44 | -2.6% | $55.94 | $56.16 | $54.16 | 2,175,778 | |
| $55.65 | -0.37 | -0.7% | $55.75 | $55.77 | $54.91 | 3,057,309 | |
| $56.02 | -0.69 | -1.2% | $56.38 | $56.96 | $55.70 | 3,037,757 | |
| $56.71 | -1.38 | -2.4% | $52.15 | $57.43 | $52.15 | 9,175,745 | |
| $58.09 | -0.04 | -0.1% | $58.36 | $58.96 | $57.78 | 2,671,092 | |
| $58.13 | -3.20 | -5.2% | $60.42 | $60.42 | $57.47 | 4,347,907 | |
| $61.33 | +1.45 | +2.4% | $60.25 | $61.77 | $59.78 | 1,845,866 | |
| $59.88 | -0.48 | -0.8% | $60.37 | $60.99 | $59.78 | 1,872,594 | |
| $60.36 | -0.69 | -1.1% | $61.07 | $61.07 | $59.70 | 2,017,160 | |
| $61.05 | -1.38 | -2.2% | $60.62 | $61.69 | $60.35 | 1,850,852 | |
| $62.43 | -0.93 | -1.5% | $63.48 | $63.48 | $62.34 | 1,625,581 | |
| $63.36 | -0.21 | -0.3% | $63.50 | $63.55 | $62.44 | 2,152,847 | |
| $63.57 | +1.53 | +2.5% | $62.53 | $64.19 | $62.19 | 2,435,239 | |
| $62.04 | +2.30 | +3.9% | $60.54 | $62.07 | $59.70 | 2,207,101 | |
| $59.74 | +0.98 | +1.7% | $59.64 | $60.92 | $59.06 | 2,723,906 | |
| $58.76 | -2.04 | -3.4% | $60.03 | $60.41 | $58.60 | 2,124,846 | |
| $60.80 | +1.18 | +2.0% | $60.11 | $61.36 | $59.61 | 3,137,560 | |
| $59.62 | +0.99 | +1.7% | $58.41 | $60.19 | $58.02 | 3,192,640 | |
| $58.63 | +1.39 | +2.4% | $57.11 | $58.74 | $56.41 | 2,000,182 | |
| $57.24 | +1.37 | +2.5% | $55.16 | $57.24 | $55.16 | 1,353,737 | |
| $55.87 | -0.66 | -1.2% | $56.50 | $56.81 | $55.56 | 1,220,460 | |
| $56.53 | +1.11 | +2.0% | $55.01 | $57.07 | $54.91 | 1,999,667 | |
| $55.42 | -1.52 | -2.7% | $56.79 | $57.16 | $55.37 | 2,407,128 | |
| $56.94 | +0.38 | +0.7% | $56.10 | $57.66 | $56.10 | 2,399,897 | |
| $56.56 | +2.07 | +3.8% | $54.73 | $56.60 | $54.40 | 2,009,277 | |
| $54.49 | +0.30 | +0.6% | $54.59 | $55.42 | $54.02 | 2,592,317 | |
| $54.19 | -0.88 | -1.6% | $55.17 | $55.36 | $53.58 | 2,122,267 | |
| $55.07 | +0.58 | +1.1% | $54.85 | $55.22 | $53.87 | 2,688,216 | |
| $54.49 | +2.72 | +5.3% | $52.66 | $54.54 | $52.17 | 3,212,858 | |
| $51.77 | -1.51 | -2.8% | $53.33 | $53.33 | $51.28 | 2,570,536 | |
| $53.28 | -0.76 | -1.4% | $53.92 | $54.04 | $52.65 | 2,875,352 | |
| $54.04 | -1.26 | -2.3% | $55.09 | $55.36 | $53.50 | 3,129,432 | |
| $55.30 | -0.66 | -1.2% | $56.56 | $56.56 | $54.00 | 2,805,274 | |
| $55.96 | -0.59 | -1.0% | $56.93 | $57.09 | $55.79 | 2,584,895 |
- Ticker
- Tradegate:ISI
- Asset type
- Stock
- Sector
- Health care
- Industry
- Biotechnology
- Exchange
- Tradegate
- Currency
- EUR
What changed lately
Latest news release · Oct 23, 2026
Ionis partner Roche announces new Phase 3 data showing sefaxersen significantly reduced proteinuria in people with IgA nephropathy (IgAN)
Latest earnings call · Jul 29, 2026
Ionis Pharmaceuticals (NASDAQ:IONS) Q2 2026 Earnings Call
Replay and transcript
Latest deck · October 2026
Investor Presentation (October 2026)
Investor deck · 39 slides
Calls
Replays
Ionis Pharmaceuticals (NASDAQ:IONS) Q2 2026 Earnings Call
Wed, Jul 29, 2026 · 8:30 AM ET
Watch TranscriptIonis Pharmaceuticals (NASDAQ:IONS) Q1 2026 Earnings Call
Wed, Apr 29, 2026 · 8:30 AM ET
Watch TranscriptIonis Pharmaceuticals (NASDAQ:IONS) Q4 2025 Earnings Call
Wed, Feb 25, 2026 · 8:30 AM ET
Watch Transcript
Latest news
Ionis partner Roche announces new Phase 3 data showing sefaxersen significantly reduced proteinuria in people with IgA nephropathy (IgAN)
Oct 23, 2026
Closed $42.93 (-2.2%) on Oct 23, 2026
Ionis ranked #1 on Science’s Top Employers list
Oct 22, 2026
Closed $43.91 (-0.8%) on Oct 22, 2026
Ionis partner GSK announces Hibsago (bepirovirsen) approved in the U.S. for the treatment of chronic hepatitis B (CHB)
Oct 20, 2026
Closed $44.27 (-2.5%) on Oct 21, 2026
TRYNGOLZA® (olezarsen) recommended for approval in the EU by CHMP for severe hypertriglyceridemia (sHTG)
Oct 16, 2026
Closed $42.94 (-2.7%) on Oct 16, 2026
Ionis announces positive interim data from partner Roche’s Phase 3 IMAgINATION study in IgA nephropathy (IgAN)
Sep 23, 2026
Closed $43.93 (-4.0%) on Sep 23, 2026
Ionis announces positive topline results from Phase 3 FUSION study of ulefnersen marking significant milestone in advancing first potential disease modifying treatment for FUS-ALS
Sep 22, 2026
Closed $45.75 (+1.9%) on Sep 22, 2026
Ionis partner Novartis announces Lp(a)HORIZON Phase 3 topline results for pelacarsen in patients with elevated Lp(a) and established cardiovascular disease (CVD)
Sep 4, 2026
Closed $56.71 (-2.4%) on Sep 8, 2026
ZANVASTRO™ (zilganersen) approved by the FDA as the first and only disease modifying treatment for Alexander disease (AxD) in pediatric and adult patients
Sep 3, 2026
Closed $58.09 (-0.1%) on Sep 4, 2026
Ionis to present new data strengthening leadership in the management of severe hypertriglyceridemia (sHTG) at the European Society of Cardiology Congress 2026
Aug 20, 2026
Closed $58.76 (-3.4%) on Aug 20, 2026
Ionis announces Dr. Frank Bennett, chief scientific officer, to retire
Jul 29, 2026
Closed $54.04 (-2.3%) on Jul 29, 2026
Decks
Investor Presentation (October 2026)
Investor deck · 39 slides · October 2026
Q2 2026 Earnings Presentation
Earnings · 28 slides · Jul 29, 2026
Technical Presentation (June 2026)
Technical · 15 slides · Jun 6, 2026
Shareholder Meeting (June 2026)
Shareholder meeting · 22 slides · June 2026
Ionis Pharmaceuticals, Inc. on 6ix
- Sector
- Health care
- Industry
- Biotechnology
- News releases
- 44 in the last 12 months · 259 in all · newest Oct 23, 2026 · oldest 2019
- Calls
- 26 calls with a replay · 26 with a transcript · latest Jul 29, 2026
- Decks
- 20 decks · latest October 2026
Where Ionis Pharmaceuticals, Inc. is listed
| Listing | Exchange | Country | Currency |
|---|---|---|---|
| NASDAQ:IONS · Home listing | NASDAQ | United States | USD |
| gettex:ISI | gettex | Germany | EUR |
| Lang & Schwarz:A2ACMZ | Lang & Schwarz | Germany | EUR |
| LS Exchange:A2ACMZ | LS Exchange | Germany | EUR |
| BX Swiss:ISI | BX Swiss | Switzerland | CHF |
| BMV:IONS | BMV | Mexico | MXN |
| Milan:1IONS | Milan | Italy | EUR |
| LSE:0JDI | LSE | United Kingdom | USD |
| Frankfurt:ISI | Frankfurt | Germany | EUR |
| Dusseldorf:ISI | Dusseldorf | Germany | EUR |
| Hamburg:ISI | Hamburg | Germany | EUR |
| Tradegate:ISI · This page | Tradegate | Germany | EUR |
| BIVA:IONS | BIVA | Mexico | MXN |
| BOATS:IONS | BOATS | United States | USD |
| Munich:ISI | Munich | Germany | EUR |
| Stuttgart:ISI | Stuttgart | Germany | EUR |
| Hanover:ISI | Hanover | Germany | EUR |
| Xetra:ISI | Xetra | Germany | EUR |
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