WuXi AppTec : 2025 WuXi AppTec Investor Day - Financial Performance

About this update from Wuxi Apptec Co., Ltd. Class A

2025 WuXi AppTec Investor Day CRDMO: Driving Sus tainable Financial Strength Florence Shi Chief Financial Officer 1 603259.SH / 2359.HK Accelerating Growth Beyond Indus try Momentum 3x WXAT Rev CAGR 2x +24% WXAT Rev Reached RMB 1.0Bn in 2007 NBI CAGR -5% WXAT Rev CAGR +23% NBI CAGR +12% NBI CAGR +8% 2000 2007 2012 2018 2025E NASDAQ Biotech Index (NBI), Bloomberg, 2000/01/01-2025/09/24 3 Expanding Competitive Advantage Through a Unique Value Proposition Seven - Year Track Record with Ongoing Momentum +7% +23% +32% +4% +13% +15% +11% 2018 2019 2020 2021 2022 2023 2024 1H'25 +37% 5 China Competitors' Revenue Combined 1) WuXi AppTec Revenue 4 1) 5 Top China Competitors in CRO & CDMO segments, same definition in the following pages Powering Rapid "D&M" Growth through Stronger "R" Capabilities 38% Backlog Growth with 55% D&M Backlog Growth 2x "R" Orders Amplifies 17x "D&M" Orders (RMB in Bn) 56.7 +38% 49.3 33.3 27.9 31.1 14x 17x 8x 7.0 10.9 14.8 2018 2019 2020 2021 2022 2023 2024 2x 1H'25 D&M Backlog R Backlog 1) 5 1) Continuing business only Delivering Indus try Insights for Optimal Capacity Planning to Secure High-Value Opportunities 41% 41% 41% 40% 42% 42% 42% New High Adj. Non-IFRS GP% @ CER 1) D&M Capex Spending Portion Increased from 28% to ~85% 1H'25 45% 2018 2019 2020 2021 2022 2023 2024 2025E Established CRDMO base Focusing on D&M Accumulated Capex Investment 2018 to 2025E - D&M Accumulated Capex Investment 2018 to 2025E - R 6 1) Restate GP% to Constant Exchange Rate Maintaining Organizational Agility and Elevating Operational Efficiency Doubling Per - Capita Productivity 50% Reduction in SG&A Ratio -50% 15.3% 14.9% 14.7% 12.7% 9.0% 8.9% 9.2% 7.5% 1,118 2x 542 2018 2019 2020 2021 2022 2023 2024 2025E 2018 2019 2020 2021 2022 2023 2024 1H'25 WuXi AppTec Per Capita Output (RMB in K) 1) WuXi AppTec Revenue (RMB in Bn) WuXi AppTec SG&A ratio as of Revenue 2) 7 1) Per Capita Output = Revenue / Ending HC 2) SG&A under PRC reporting Proven Resilient Profitability Through the CRDMO Model, Operating Strategy and Outs tanding Execution 18% Adj. Non-IFRS NI% New High 18% 22% 22% 27% 24% 27% 1H'25 30% 9.4 10.9 10.6 5.1 1.7 2.3 3.6 Revenue CAGR 24% vs Adj. Non-IFRS NI CAGR 30%+ Adj. Non-IFRS NI (RMB in Bn) 2018 2019 2020 2021 2022 2023 2024 2025E 8 Fueling Robust Operating Cash Flow Through the CRDMO Model and Efficiency Gains 2.4x 35% 31% 31% 26% 23% 20% 19% 16% 12.6 12.0 10.2 3.8 4.4 1.5 2.5 2018 2019 2020 2021 2022 2023 2024 2025E WuXi AppTec - IFRS OCF (RMB in Bn) OCF Ratio = OCF / Revenue 9 Enabling Value Creation and Consis tent Shareholder Returns Continuously Improved EPS Total RMB 20Bn Dividends & Share Buybacks Basic Earning Per Share Dividend Payout & Share Buybacks for Cancellation ~7x 3.0 3.3 3.3 1.8 0.7 1.1 7.1 6.8 2.9 4.2 2.0 0.7 0.6 0.9 4.8 1.5 2.6 2019 2020 2021 2022 2023 2024 2025E 2019 2020 2021 2022 2023 2024 2025 WuXi AppTec PRC Basic EPS (RMB) 1) 1) Restate 2019 & 2020 EPS to reflect the changes in shares volume according to 2020 Profit Distribution Plan as per 2020 Annual Report Dividends Declared (RMB in Bn) Share Buybacks for Cancellation (RMB in Bn) Outperforming Total Shareholder Return Total Shareholder Return (TSR) total return in 7 years WuXi AppTec: 12.3x CXO index: China 3.3x / & Globa l 1.5x Biotech: Nasda q 1.7x / S&P 1.2x Healthcare index: S&P 1200 Health Index 2.0x Total Shareholder Return from 2018/5/8 to 2025/9/24 Source: Bloomberg (Total Shareholder Return since IPO) Total Shareholder Return is the growth in value of a shareholding over a specified period, assuming dividends are reinvested to purchase additional units of stock Steering Next 25 Years with Our Unique CRDM"O" Expanding Competitive Advantage Through Our Unique CRDMO Business Model 01 02 Delivering In-depth Industry Insights to Secure High-Value Opportunities 03 Maintaining Organizational Agility and Elevating Operational Efficiency 04 Sustaining Resilient Profitability and Operating Cash Flow 05 Enabling Value Creation and Consistent Shareholder Returns 12 Attention : This is an excerpt of the original content. To continue reading it, access the original document here .

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