Polypid Ltd.NASDAQ: PYPD

Investor Presentation (3e767d)

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NASDAQ: PYPD Corporate Presentation

August 2025



PolyPid Overview

Polymer-Lipid Encapsulation matriX (PLEX) Platform

granted and pending patents(1)

Pre-NDA

Lead Product D-PLEX in

stage biopharma company

Unique LOCAL Prolonged Delivery of APIs

Phase 3 trial

OncoPLEX Next Big Opportunity for Solid Tumors

100

employees(1)

Global: Petach Tikva, Israel

US: New Jersey

NASDAQ: PYPD

3

1 As of August '25







Robust Pipeline with Multiple Near- and Longer-Term Inflection Points
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