Many Bright Ideas Technologies IncTSXV: MBI.H

Med BioGene reports promising pre-clinical results of its Diagnostic Lymphoma DNA Bioarray; biomarkers effective in diagnosing major lymphoma subtypes

· Issued by Many Bright Ideas Technologies Inc via CNW
VANCOUVER, Aug. 3 /CNW/ - Med BioGene Inc. (TSX Venture: MBI) is pleased
to announce the results of its pre-clinical studies involving its Diagnostic
Lymphoma Bioarray. The studies of fifty RNA samples derived from human
lymphoma tissues suggest that MBI's Diagnostic Lymphoma Bioarray successfully
differentiated between genes in both the diseased and healthy control samples.
Moreover, the results revealed a high dissimilarity between six lymphoma
subtypes (Diffuse Large B-Cell, Mantle Cell, Follicular, Hodgkin, Marginal
Zone and Small Lymphocytic) and the healthy control samples, indicating that
the bioarray is able to detect differential expression profiles. The samples
used in the studies did not include the subtype T-Cell Lymphoma; however,
prior studies suggest that the bioarray is able to distinguish this subtype
from healthy control samples. Sample replicates were also highly similar to
one another, indicating a consistency in the bioarray.
"We are very pleased with these results and are enthusiastic about the
prospects of our Diagnostic Lymphoma Bioarray as an effective tool for the
accurate and rapid detection of lymphoma subtypes. We have been able to narrow
our lymphoma biomarkers to approximately 100 genes, thus increasing the
effectiveness of the product as a manageable diagnostic tool. Further studies,
however, may result in the finding of additional biomarkers that will be
included in our bioarray. These studies were performed on GE Healthcare's
CodeLink System using custom bioarrays made exclusively for, and containing
genetic content developed by, Med BioGene. We are also in the process of
confirming our results on a second platform utilizing Applied BioSystem's 7500
Real-Time PCR System", noted Dr. T. Nathan Yoganathan, Chief Scientific
Officer of MBI.
"In addition to the use of our bioarray as a diagnostic tool, there is an
increasing consensus in the medical community that effective biomarkers are
needed to unlock innovation in therapeutic development and treatment. With a
robust set of qualified lymphoma biomarkers, the safety of new therapeutics
could be increased, products could get to patients in less time and treatment
decisions could be more informed. Med BioGene is truly at the forefront of
personalized medicine", stated Erinn Broshko, Chief Executive Officer of MBI.

About Med BioGene

MBI is a biotechnology company with advanced research expertise in gene
expression technology. MBI is at the forefront of personalized medicine and
it's mission is to become the market leader in the supply of content for
molecular-based diagnostic micro arrays. MBI intends to fulfill this mission
by developing and marketing genetic content for molecular-based human
diagnostic tests. Molecular diagnostics, based on genetic expression, is a
developing technology field that has the potential to replace certain of
today's standard diagnostic tests. MBI intends to utilize its expertise in
gene expression, bioinformatics and micro arrays to develop the diagnostic
tests' genetic content. From the tens of thousands of genes in the human
genome, MBI is identifying those genes, known as "biomarkers," which mark the
presence of various disease conditions.
MBI is initially developing diagnostic tests for certain types of cancer,
specifically lymphoma and leukemia. In the future, MBI intends to develop
diagnostic tests to identify the earliest stages of heart disease or the
presence of an infectious disease. These diagnostic test kits will be designed
to provide additional information to physicians to allow them to create more
suitable and more effective treatments for an improved patient prognosis.

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or accuracy of this release.

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the timing of clinical trials and the completion date for clinical trials and
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disclosed in its forward-looking information. Forward-looking information is
subject to known and unknown risks and uncertainties and are based on
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events to differ materially from those anticipated in such forward-looking
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forward-looking information, which speaks only as of the date of this press
release. Our forward-looking information does not reflect the potential impact
of any future partnerships, collaborations, acquisitions, mergers,
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information is qualified in its entirety by this cautionary statement and MBI
undertakes no obligation to revise or update any forward-looking information
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