KRTL Holding Group Inc. and Industria Químico Farmacéutica Sigma Corp. S.R.L. Announce Mutual Rescission of Merger Agreement

About this update from Krtl Holding Group, Inc

KRTL Holding Group Inc. (“KRTL” or the “Company”) today announced that KRTL Biotech Inc., a wholly owned subsidiary of KRTL Holding Group Inc., and Industria Químico Farmacéutica Sigma Corp. S.R.L. (“Sigma”) have mutually agreed to rescind their previously announced merger transaction following a comprehensive evaluation of regulatory strategy and long-term execution priorities. No termination fee was paid by either party in connection with the recission.   The shares of common and preferred stock issued to Sigma shareholders by the Company and by KRTL Biotech were returned to the Company. Through continued collaboration, the parties determined that advancing under a revised regulatory and transactional framework provides a more efficient and effective path forward, particularly with respect to regulatory alignment, compliance sequencing, and continuity of operations. This approach allows each organization to pursue aligned objectives through structures best suited to the timing and progression of applicable regulatory and business milestones. In parallel, KRTL continues to advance initiatives involving certain proprietary intellectual property assets that are integral to the Company’s long-term growth strategy and regulatory roadmap. These initiatives are being pursued under appropriately structured arrangements designed to support regulatory compliance, operational scalability, and sustainable value creation. The Company expects to provide additional updates as these initiatives reach appropriate regulatory and commercial milestones. “We value the constructive working relationship established with Sigma and appreciate the collaborative approach taken throughout this process,” said Cesar Herrera, Chief Executive Officer of KRTL Holding Group Inc. “This strategic update reflects a disciplined focus on regulatory advancement and execution efficiency, while preserving opportunities for continued alignment where appropriate.” Both companies intend to maintain a positive working relationship and continue evaluating potential future initiatives under frameworks that best support their respective regulatory and business objectives. KRTL remains committed to strong governance, transparency, and the prudent advancement of strategic initiatives aligned with shareholder interests and long-term value creation.   About KRTL Holding Group, Inc. KRTL Holding Group, Inc. (OTC: KRTL) operates through its subsidiaries KRTL Biotech, Inc. and KRTL International Corp. The Company leverages strategic synergies across biotech, technology, and emerging markets to drive growth and deliver shareholder value.   For more information: www.krtlholding.com | www.krtl-icc.com | www.krtlbiotech.com |   Forward-Looking Statements This press release contains statements and information that, to the extent that they are not historical fact, may constitute   “forward-looking statements” within the meaning of applicable securities legislation. These statements relate to future events or our future financial performance and involve known and unknown risks, uncertainties, and other factors that may cause our actual results, performance, or achievements to differ materially from any future results, performance, or achievements expressed or implied by these forward-looking statements. Words such as “anticipates,” “will,” “believes,” “plans,” “expects,” “intends,” “projects,” “estimates,” “future,” and “opportunity” and similar expressions are used to identify these forward-looking statements. Forward-looking statements are not guarantees of future performance. Examples of such statements include, but are not limited to, statements with respect to the objectives and business plans of the Company; ability to realize benefits from its recent corporate appointments and acquisitions; ability to retain its key personnel; the intention to grow the Company’s business and operations; the competitive conditions of the industries in which the Company operates; and laws and any amendments thereto applicable to the Company. Forward-looking information is based on the assumptions, estimates, analysis and opinions of management made in light of its experience and its perception of trends, current conditions and expected developments, as well as other factors that management believes to be relevant and reasonable in the circumstances at the date that such statements are made, but which may prove to be incorrect. Forward-looking information involves known and unknown risks, uncertainties and other factors that may cause the actual results, performance or achievements of the Company to differ materially from any future results, performance or achievements expressed or implied by the forward-looking information, including, without limitation, risks relating to the future business plans of the Company; risks that the Company will not be able to retain its key personnel; risks that the Company will not be able to secure financing on reasonable terms or at all, as well as all of the other risks. Accordingly, readers should not place undue reliance on any such forward-looking information. Further, any forward-looking information speaks only as of the date on which such statement is made. New factors emerge from time to time, and it is not possible for the Company’s management to predict all of such factors and to assess in advance the impact of each such factor on the Company’s business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking information. The Company does not undertake any obligation to update any forward-looking information to reflect information or events after the date on which it is made or to reflect the occurrence of unanticipated events, except as required by law.

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