Amplia Announces Publication of New FAK Inhibitor Patent Application

About this update from Amplia Therapeutics Ltd.

HIGHLIGHTS Melbourne, Australia, July 09, 2026 (GLOBE NEWSWIRE) -- Amplia Therapeutics Limited (ASX:ATX; OTCQB:INNMF), ("Amplia" or the "Company"), is pleased to announce publication of a new patent application describing chemically novel inhibitors of focal adhesion kinase (FAK) discovered by the Company. The patent application further expands Amplia's FAK intellectual property portfolio and, if granted, would provide protection for the novel molecules described, and their use, out to 2046. Amplia's patent portfolio covers its lead drug narmafotinib, currently in clinical trials for pancreatic and ovarian cancer, and a second drug candidate (AMP886) being investigated in preclinical studies. The new patent application describes additional chemical compounds closely related to narmafotinib that also demonstrate potent and selective activity against FAK. These molecules broaden Amplia's development pipeline and may provide future opportunities for evaluation across additional indications. Importantly, the patent application adds depth to the Company's existing intellectual property estate around its FAK inhibitor program and supports the long-term commercial value of its development assets. Dr. Chris Burns, CEO and Managing Director of Amplia, commented, "This patent application further strengthens our portfolio of potent FAK inhibitors and highlights the depth of innovation being generated by the Company. In addition to supporting narmafotinib, it creates future development and partnering optionality through a broader suite of novel molecules targeting this important pathway." This announcement was approved and authorised for release by the CEO of Amplia Therapeutics. About Amplia Therapeutics Limited Amplia Therapeutics Limited is an Australian pharmaceutical company advancing a pipeline of Focal Adhesion Kinase (FAK) inhibitors for cancer and fibrosis. FAK is an increasingly important target in the field of cancer and Amplia has a particular development focus in fibrotic cancers such as pancreatic and ovarian cancer. FAK also plays a significant role in a number of chronic diseases, such as idiopathic pulmonary fibrosis (IPF). For more information visit www.ampliatx.com and follow Amplia on X (@ampliatx) and LinkedIn.

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