State Street(R) SPDR(R) S&P(R) Biotech ETF

State Street(R) SPDR(R) S&P(R) Biotech ETF reported 157 holdings worth US$10.7B as of Jun 30, 2026 (Form N-PORT)

As of Jun 30, 2026 · Filed Aug 28, 2026

State Street(R) SPDR(R) S&P(R) Biotech ETF reported 157 holdings worth US$10.7B as of Jun 30, 2026. Largest: Apogee Therapeutics, Inc., Moderna, Inc. and Twist Bioscience Corporation. Filed Aug 28, 2026 (Form N-PORT).

Holdings
157
Value as reported
US$10.7B

The filing in full

CompanySharesValue as reported% of portfolio
Apogee Therapeutics, Inc.1.2MUS$160M1.5%
Moderna, Inc.2.16MUS$152M1.4%
Twist Bioscience Corporation1.47MUS$151M1.4%
Oruka Therapeutics, Inc.1.56MUS$148M1.4%
Kymera Therapeutics, Inc.1.27MUS$146M1.4%
Viking Therapeutics, Inc.3.59MUS$140M1.3%
Praxis Precision Medicines, Inc.414KUS$139M1.3%
Erasca, Inc.7.45MUS$136M1.3%
Revolution Medicines, Inc.690KUS$129M1.2%
Rhythm Pharmaceuticals, Inc.1.16MUS$129M1.2%
Cg Oncology, Inc.1.81MUS$129M1.2%
Sellas Life Sciences Group, Inc.8.65MUS$128M1.2%
Vaxcyte, Inc.2.19MUS$127M1.2%
Dianthus Therapeutics, Inc.1.3MUS$127M1.2%
Cytokinetics, Incorporated1.48MUS$126M1.2%
Natera, Inc.460KUS$125M1.2%
Scholar Rock Holding Corporation2.26MUS$124M1.2%
Roivant Sciences Ltd.3.5MUS$124M1.2%
Mirum Pharmaceuticals, Inc.1.06MUS$124M1.2%
Cogent Biosciences, Inc.3.17MUS$123M1.1%
Ultragenyx Pharmaceutical Inc.3.67MUS$122M1.1%
Travere Therapeutics, Inc.2.13MUS$121M1.1%
Alkermes Plc2.27MUS$119M1.1%
Krystal Biotech, Inc.319KUS$118M1.1%
Celcuity Inc.1.13MUS$118M1.1%
Relay Therapeutics, Inc.6.3MUS$118M1.1%
Spyre Therapeutics, Inc.1.33MUS$118M1.1%
Tg Therapeutics, Inc.2.14MUS$117M1.1%
Beam Therapeutics Inc.3.38MUS$116M1.1%
Insmed Incorporated1.08MUS$116M1.1%
Protagonist Therapeutics, Inc.941KUS$115M1.1%
Arrowhead Pharmaceuticals, Inc.1.41MUS$115M1.1%
Vera Therapeutics, Inc.2.65MUS$114M1.1%
Vertex Pharmaceuticals Incorporated228KUS$113M1.1%
Madrigal Pharmaceuticals, Inc.211KUS$113M1.1%
Abbvie Inc.443KUS$111M1.0%
Biogen Inc.513KUS$111M1.0%
Ptc Therapeutics, Inc.1.36MUS$111M1.0%
Halozyme Therapeutics, Inc.1.41MUS$111M1.0%
Uniqure N.v.2.4MUS$110M1.0%
Bridgebio Pharma, Inc.1.48MUS$110M1.0%
Crispr Therapeutics Ag2.01MUS$110M1.0%
Immunitybio, Inc.12.5MUS$109M1.0%
Summit Therapeutics Inc.7.45MUS$109M1.0%
Ionis Pharmaceuticals, Inc.1.36MUS$108M1.0%
Incyte Corporation945KUS$107M1.00%
Amgen Inc.295KUS$107M0.99%
Neurocrine Biosciences, Inc.619KUS$104M0.97%
Gilead Sciences, Inc.820KUS$104M0.96%
Regeneron Pharmaceuticals, Inc.165KUS$103M0.96%
Exelixis, Inc.1.89MUS$103M0.96%
Alnylam Pharmaceuticals, Inc.342KUS$103M0.96%
Biomarin Pharmaceutical Inc.1.77MUS$101M0.94%
Acadia Pharmaceuticals Inc.3.98MUS$101M0.94%
Nuvalent, Inc.807KUS$99.7M0.93%
Immunovant, Inc.2.58MUS$99.3M0.92%
United Therapeutics Corporation183KUS$99.2M0.92%
Intellia Therapeutics, Inc.5.76MUS$97.4M0.91%
Grail, Inc.1.43MUS$97.3M0.91%
Biocryst Pharmaceuticals, Inc.9.58MUS$95.8M0.89%
Catalyst Pharmaceuticals, Inc.2.99MUS$93.8M0.87%
Dyne Therapeutics, Inc.4.15MUS$92.2M0.86%
Tango Therapeutics, Inc.2.89MUS$90.4M0.84%
Denali Therapeutics Inc.3.48MUS$89.4M0.83%
Veracyte, Inc.1.5MUS$87.9M0.82%
Ideaya Biosciences, Inc.2.31MUS$86.3M0.80%
Recursion Pharmaceuticals, Inc.22.1MUS$81.2M0.76%
Sarepta Therapeutics, Inc.4.46MUS$80.2M0.75%
Arcus Biosciences, Inc.2.59MUS$79.8M0.74%
Syndax Pharmaceuticals, Inc.3.53MUS$77.1M0.72%
Arcutis Biotherapeutics, Inc.2.91MUS$76.4M0.71%
Mineralys Therapeutics, Inc.2.82MUS$76.1M0.71%
Celldex Therapeutics, Inc.2.03MUS$75.4M0.70%
Agios Pharmaceuticals, Inc.2.01MUS$74.4M0.69%
Viridian Therapeutics, Inc.3.92MUS$72.1M0.67%
Novavax, Inc.7.53MUS$70.9M0.66%
Disc Medicine, Inc.959KUS$70.1M0.65%
Adma Biologics Inc7.79MUS$65.2M0.61%
Immunome, Inc.2.99MUS$63.4M0.59%
Palvella Therapeutics, Inc.409KUS$62.5M0.58%
Iovance Biotherapeutics, Inc.14.5MUS$60.3M0.56%
Absci Corporation5.17MUS$59.9M0.56%
Nurix Therapeutics, Inc.2.46MUS$59.7M0.56%
Kodiak Sciences Inc1.5MUS$58.3M0.54%
Biohaven Ltd.3.79MUS$56.4M0.53%
Vericel Corporation1.19MUS$53.1M0.49%
Anaptysbio, Inc.787KUS$53.1M0.49%
Capricor Therapeutics, Inc.2.18MUS$52.5M0.49%
Stoke Therapeutics, Inc.1.57MUS$51.5M0.48%
Monte Rosa Therapeutics, Inc.2.11MUS$51.2M0.48%
Vir Biotechnology, Inc.4.95MUS$50.4M0.47%
Hyperliquid Strategies Inc6.33MUS$49.8M0.46%
Tyra Biosciences, Inc.1.39MUS$44.5M0.41%
Corvus Pharmaceuticals, Inc.2.93MUS$43.8M0.41%
Cullinan Therapeutics, Inc.2.38MUS$43.3M0.40%
Precigen, Inc.7.09MUS$40.4M0.38%
Inhibrx Biosciences, Inc.401KUS$38M0.35%
Taysha Gene Therapies, Inc.5.57MUS$37.9M0.35%
Ardelyx, Inc.7.42MUS$37.8M0.35%
Avalo Therapeutics, Inc.2.03MUS$37.5M0.35%

Every holding of State Street(R) SPDR(R) S&P(R) Biotech ETF

Source

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