| Alkermes Plc | 172K | US$7.24M | 4.5% |
| Kymera Therapeutics, Inc. | 84,154 | US$6.85M | 4.2% |
| Celcuity Inc. | 47,693 | US$6.34M | 3.9% |
| Mirum Pharmaceuticals, Inc. | 62,199 | US$6.31M | 3.9% |
| Spyre Therapeutics, Inc. | 80,958 | US$5.95M | 3.7% |
| Cg Oncology, Inc. | 87,032 | US$5.42M | 3.4% |
| Apogee Therapeutics, Inc. | 57,722 | US$4.74M | 2.9% |
| Xenon Pharmaceuticals Inc. | 85,746 | US$4.69M | 2.9% |
| Travere Therapeutics, Inc. | 95,051 | US$4.48M | 2.8% |
| Dianthus Therapeutics, Inc. | 45,839 | US$4.26M | 2.6% |
| Newamsterdam Pharma Company N.v. | 119K | US$3.99M | 2.5% |
| Viking Therapeutics, Inc. | 119K | US$3.9M | 2.4% |
| Crinetics Pharmaceuticals, Inc. | 108K | US$3.84M | 2.4% |
| Acadia Pharmaceuticals Inc. | 176K | US$3.81M | 2.4% |
| Edgewise Therapeutics, Inc. | 111K | US$3.78M | 2.3% |
| Denali Therapeutics Inc. | 163K | US$3.44M | 2.1% |
| Oruka Therapeutics, Inc. | 49,896 | US$2.92M | 1.8% |
| Disc Medicine, Inc. | 39,334 | US$2.74M | 1.7% |
| Ideaya Biosciences, Inc. | 90,520 | US$2.67M | 1.6% |
| Vera Therapeutics, Inc. | 73,552 | US$2.61M | 1.6% |
| Tarsus Pharmaceuticals, Inc. | 43,870 | US$2.61M | 1.6% |
| Relay Therapeutics, Inc. | 184K | US$2.59M | 1.6% |
| Mineralys Therapeutics, Inc. | 81,578 | US$2.57M | 1.6% |
| Celldex Therapeutics, Inc. | 68,615 | US$2.16M | 1.3% |
| Zai Lab Ltd. | 1.15M | US$2.03M | 1.3% |
| Pharvaris N.v. | 66,026 | US$1.99M | 1.2% |
| Sionna Therapeutics, Inc. | 46,379 | US$1.99M | 1.2% |
| Rapport Therapeutics, Inc. | 49,264 | US$1.95M | 1.2% |
| Sarepta Therapeutics, Inc. | 108K | US$1.93M | 1.2% |
| Lakefront Biotherapeutics | 68,075 | US$1.93M | 1.2% |
| Tyra Biosciences, Inc. | 55,509 | US$1.85M | 1.1% |
| Novavax, Inc. | 168K | US$1.84M | 1.1% |
| Stoke Therapeutics, Inc. | 58,873 | US$1.82M | 1.1% |
| Agios Pharmaceuticals, Inc. | 60,392 | US$1.78M | 1.1% |
| Vericel Corporation | 52,309 | US$1.74M | 1.1% |
| Nuvation Bio Inc. | 357K | US$1.71M | 1.1% |
| Palvella Therapeutics, Inc. | 14,096 | US$1.67M | 1.0% |
| Taysha Gene Therapies, Inc. | 282K | US$1.66M | 1.0% |
| Amylyx Pharmaceuticals, Inc. | 114K | US$1.63M | 1.0% |
| Immatics N.v. | 138K | US$1.59M | 0.98% |
| Mbx Biosciences, Inc. | 46,286 | US$1.46M | 0.90% |
| Bicara Therapeutics Inc. | 65,313 | US$1.42M | 0.88% |
| Moonlake Immunotherapeutics | 73,934 | US$1.42M | 0.88% |
| Kalvista Pharmaceuticals, Inc. | 52,105 | US$1.4M | 0.87% |
| Arrivent Biopharma, Inc. | 45,563 | US$1.38M | 0.85% |
| Oculis Holding Ag | 58,929 | US$1.35M | 0.84% |
| Maze Therapeutics, Inc. | 49,602 | US$1.31M | 0.81% |
| Mannkind Corporation | 318K | US$1.2M | 0.74% |
| Corvus Pharmaceuticals, Inc. | 86,347 | US$1.07M | 0.66% |
| Olema Pharmaceuticals, Inc. | 81,077 | US$1.07M | 0.66% |
| Zenas Biopharma, Inc. | 55,332 | US$1.02M | 0.63% |
| Kura Oncology, Inc. | 91,050 | US$929K | 0.57% |
| Ars Pharmaceuticals, Inc. | 102K | US$928K | 0.57% |
| Xencor, Inc. | 75,597 | US$898K | 0.56% |
| Theravance Biopharma, Inc. | 52,230 | US$839K | 0.52% |
| Geron Corporation | 660K | US$825K | 0.51% |
| Design Therapeutics, Inc. | 63,568 | US$666K | 0.41% |
| Alto Neuroscience, Inc. | 32,025 | US$643K | 0.40% |
| Candel Therapeutics, Inc. | 75,500 | US$627K | 0.39% |
| Tectonic Therapeutic, Inc. | 19,353 | US$603K | 0.37% |
| Fulgent Genetics, Inc. | 32,191 | US$584K | 0.36% |
| Rigel Pharmaceuticals, Inc. | 19,042 | US$581K | 0.36% |
| Aclaris Therapeutics, Inc. | 124K | US$566K | 0.35% |
| Upstream Bio, Inc. | 55,699 | US$466K | 0.29% |
| Neurogene Inc. | 15,968 | US$453K | 0.28% |
| Compass Therapeutics, Inc. | 186K | US$442K | 0.27% |
| Altimmune, Inc. | 134K | US$409K | 0.25% |
| Vanda Pharmaceuticals Inc. | 60,925 | US$393K | 0.24% |
| Delcath Systems, Inc. | 35,814 | US$386K | 0.24% |
| Atea Pharmaceuticals, Inc. | 82,125 | US$384K | 0.24% |
| Zura Bio Limited | 88,879 | US$382K | 0.24% |
| Regenxbio Inc. | 53,200 | US$373K | 0.23% |
| Rezolute, Inc. | 98,643 | US$326K | 0.20% |
| Anavex Life Sciences Corp. | 95,522 | US$289K | 0.18% |
| Akebia Therapeutics, Inc. | 276K | US$282K | 0.17% |
| Protara Therapeutics, Inc. | 55,748 | US$259K | 0.16% |
| Forte Biosciences, Inc. | 12,912 | US$246K | 0.15% |
| Arcturus Therapeutics Holdings Inc. | 29,289 | US$232K | 0.14% |
| Aardvark Therapeutics, Inc. | 22,439 | US$92,224 | 0.06% |
| Apellis Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |