| Edgewise Therapeutics, Inc. | 15.5M | US$631M | 11.7% |
| Enliven Therapeutics, Inc. | 6.78M | US$344M | 6.4% |
| Eli Lilly And Company | 258K | US$309M | 5.7% |
| Mbx Biosciences, Inc. | 3.43M | US$189M | 3.5% |
| Sinovac Biotech, Ltd. | 2.72M | US$184M | 3.4% |
| Sionna Therapeutics, Inc. | 2.56M | US$112M | 2.1% |
| Corvus Pharmaceuticals, Inc. | 7.17M | US$107M | 2.0% |
| Arrivent Biopharma, Inc. | 3.03M | US$105M | 1.9% |
| Guardant Health, Inc. | 584K | US$87.6M | 1.6% |
| Argenx Se | 92,880 | US$86.2M | 1.6% |
| Merck & Company, Inc. | 663K | US$85.2M | 1.6% |
| Praxis Precision Medicines, Inc. | 230K | US$77M | 1.4% |
| Edwards Lifesciences Corporation | 835K | US$75.5M | 1.4% |
| Prelude Therapeutics Incorporated | 13.7M | US$73.2M | 1.4% |
| Abivax Sa | 547K | US$72.8M | 1.3% |
| Dyne Therapeutics, Inc. | 3.24M | US$71.9M | 1.3% |
| Natera, Inc. | 262K | US$71.1M | 1.3% |
| Cg Oncology, Inc. | 973K | US$69.1M | 1.3% |
| Unitedhealth Group Incorporated | 161K | US$67M | 1.2% |
| Ars Pharmaceuticals, Inc. | 8.29M | US$66.4M | 1.2% |
| Humana Inc. | 164K | US$65.2M | 1.2% |
| Cogent Biosciences, Inc. | 1.68M | US$65.1M | 1.2% |
| Boston Scientific Corporation | 1.48M | US$63.3M | 1.2% |
| Intuitive Surgical, Inc. | 158K | US$62.8M | 1.2% |
| Mineralys Therapeutics, Inc. | 2.11M | US$56.9M | 1.1% |
| Odyssey Therapeutics, Inc. | 3M | US$56.2M | 1.0% |
| Xenon Pharmaceuticals Inc. | 892K | US$53.9M | 1.00% |
| Arcutis Biotherapeutics, Inc. | 2.04M | US$53.5M | 0.99% |
| Bristol-myers Squibb Company | 925K | US$53.3M | 0.99% |
| Q32 Bio Inc. | 4.13M | US$52.6M | 0.97% |
| Stryker Corporation | 159K | US$50.1M | 0.93% |
| Caris Life Sciences, Inc. | 2.81M | US$50M | 0.93% |
| Thermo Fisher Scientific Inc | 90,700 | US$45.5M | 0.84% |
| Palvella Therapeutics, Inc. | 292K | US$44.7M | 0.83% |
| Elevance Health, Inc. | 115K | US$44.4M | 0.82% |
| Shattuck Labs, Inc. | 6.31M | US$43.8M | 0.81% |
| Upstream Bio, Inc. | 5.69M | US$39.4M | 0.73% |
| Crinetics Pharmaceuticals, Inc. | 999K | US$37.4M | 0.69% |
| Rhythm Pharmaceuticals, Inc. | 323K | US$35.9M | 0.66% |
| Syndax Pharmaceuticals, Inc. | 1.54M | US$33.7M | 0.62% |
| Forte Biosciences, Inc. | 1.58M | US$33.5M | 0.62% |
| Compass Therapeutics, Inc. | 15.2M | US$33.3M | 0.62% |
| Nektar Therapeutics | 465K | US$32.5M | 0.60% |
| Krystal Biotech, Inc. | 83,200 | US$30.9M | 0.57% |
| Axsome Therapeutics, Inc. | 118K | US$28.8M | 0.53% |
| Trevi Therapeutics, Inc. | 1.43M | US$26.7M | 0.49% |
| Disc Medicine, Inc. | 358K | US$26.2M | 0.48% |
| West Pharmaceutical Services, Inc. | 70,600 | US$25.3M | 0.47% |
| Relmada Therapeutics, Inc. | 3.63M | US$25.1M | 0.47% |
| Sutro Biopharma, Inc. | 744K | US$24.7M | 0.46% |
| Savara, Inc. | 3.96M | US$24.4M | 0.45% |
| Neuropace, Inc. | 1.51M | US$23.9M | 0.44% |
| Aura Biosciences, Inc. | 3.33M | US$23.7M | 0.44% |
| Oric Pharmaceuticals, Inc. | 2.02M | US$21.8M | 0.40% |
| Cybin, Inc. | 3.27M | US$21.6M | 0.40% |
| Biocryst Pharmaceuticals, Inc. | 1.85M | US$18.5M | 0.34% |
| Bioage Labs, Inc. | 752K | US$18.4M | 0.34% |
| Lexeo Therapeutics, Inc. | 3.95M | US$18.4M | 0.34% |
| Whitehawk Therapeutics, Inc. | 3.93M | US$18M | 0.33% |
| Definium Therapeutics, Inc. | 365K | US$17.2M | 0.32% |
| Spyre Therapeutics, Inc. | 186K | US$16.5M | 0.31% |
| Corbus Pharmaceuticals Holdings, Inc. | 1.74M | US$16.3M | 0.30% |
| Vera Therapeutics, Inc. | 370K | US$15.9M | 0.29% |
| Alumis Inc. | 548K | US$15.4M | 0.29% |
| Eyepoint, Inc. | 1.07M | US$15.3M | 0.28% |
| Waters Corporation | 40,300 | US$15.1M | 0.28% |
| Monopar Therapeutics Inc. | 157K | US$14.6M | 0.27% |
| Travere Therapeutics, Inc. | 253K | US$14.4M | 0.27% |
| Taysha Gene Therapies, Inc. | 2M | US$13.6M | 0.25% |
| Biogen Inc. | 61,600 | US$13.3M | 0.25% |
| Revolution Medicines, Inc. | 70,500 | US$13.2M | 0.24% |
| Dianthus Therapeutics, Inc. | 115K | US$11.2M | 0.21% |
| Spruce Biosciences, Inc. | 200K | US$10.8M | 0.20% |
| Lifestance Health Group, Inc. | 947K | US$10.1M | 0.19% |
| Erasca, Inc. | 496K | US$9.08M | 0.17% |
| Protara Therapeutics, Inc. | 2.22M | US$8.48M | 0.16% |
| Keros Therapeutics, Inc. | 759K | US$8.12M | 0.15% |
| Janux Therapeutics, Inc. | 525K | US$8.06M | 0.15% |
| Tectonic Therapeutic, Inc. | 227K | US$7.79M | 0.14% |
| Adicet Bio, Inc. | 845K | US$7.3M | 0.14% |
| Alto Neuroscience, Inc. | 258K | US$6.8M | 0.13% |
| Zentalis Pharmaceuticals, Inc. | 1.39M | US$6.74M | 0.12% |
| Bright Minds Biosciences Inc. | 93,000 | US$6.53M | 0.12% |
| Alx Oncology Holdings Inc. | 2.87M | US$5.93M | 0.11% |
| Xilio Therapeutics, Inc. | 592K | US$5.67M | 0.11% |
| Bicara Therapeutics Inc. | 191K | US$5.67M | 0.11% |
| Imagenebio, Inc. | 909K | US$5.36M | 0.10% |
| Protagonist Therapeutics, Inc. | 42,100 | US$5.16M | 0.10% |
| Alnylam Pharmaceuticals, Inc. | 17,000 | US$5.12M | 0.09% |
| Palisade Bio, Inc. | 2.33M | US$4.88M | 0.09% |
| Ataibeckley Inc. | 798K | US$4.2M | 0.08% |
| Ptc Therapeutics, Inc. | 49,100 | US$4.01M | 0.07% |
| Artivion, Inc. | 175K | US$3.93M | 0.07% |
| Neumora Therapeutics, Inc. | 2.14M | US$3.64M | 0.07% |
| Acadia Pharmaceuticals Inc. | 137K | US$3.47M | 0.06% |
| Amylyx Pharmaceuticals, Inc. | 183K | US$3.29M | 0.06% |
| Tyra Biosciences, Inc. | 102K | US$3.26M | 0.06% |
| Rapport Therapeutics, Inc. | 76,616 | US$3.19M | 0.06% |
| Tarsus Pharmaceuticals, Inc. | 35,581 | US$2.24M | 0.04% |
| Aclaris Therapeutics, Inc. | 422K | US$2.23M | 0.04% |