Upstream Bio, Inc. · NASDAQ:UPB
Upstream Bio, Inc. shareholders
As of Jun 30, 2026, 143 institutions reported holding Upstream Bio, Inc., 92.3% of its shares. Largest: Fidelity, Orbimed Advisors LLC and Norges Bank. New holders, exits, insiders and big stakes, each with its filing.
| Holder | Shares | % of Upstream Bio, Inc. | Change | Filed |
|---|---|---|---|---|
| Fidelity | 8.16M | 14.9% | +61,334 | Aug 13, 2026 |
| Orbimed Advisors LLC | 5.69M | 10.4% | no change | Aug 14, 2026 |
| Norges Bank | 3.77M | 6.9% | first report | Aug 12, 2026 |
| BlackRock | 3.75M | 6.9% | +383K | Aug 7, 2026 |
| Vanguard | 2.87M | 5.2% | +17,049 | Aug 13, 2026 |
| Decheng Capital LLC | 2.72M | 5.0% | no change | Aug 14, 2026 |
| Enavate Sciences Gp, LLC | 2.46M | 4.5% | no change | Aug 14, 2026 |
| Millennium | 1.14M | 2.1% | +206K | Aug 14, 2026 |
| D. E. Shaw & Co., Inc. | 1.04M | 1.9% | +216K | Aug 14, 2026 |
| JPMorgan | 1.01M | 1.8% | +549K | Aug 12, 2026 |