Takara Bio Inc.TSE: 4974

Financial Results Presentation (November 15, 2022)

· Issued by Takara Bio Inc.

Financial Results for the Second Quarter Ended September 30, 2022

November 15, 2022

This is an English translation from Japanese presentation material.

Contents

  • Consolidated Financial Results for the Second Quarter Ended September 30, 2022
  • Consolidated Financial Forecast for the Year Ending March 31, 2023
  • Business Progress and Future Measures

1

Consolidated Quarterly Financial Results for FY2023

(for the 2nd Quarter Ended September 30, 2022)

Actual

Y/Y

Comparison

(million yen)

with May 12

forecast

Net sales

32,587

+1,035

+4,842

+3.3%

+17.5%

[1]

27,565

+2,576

+4,989

Reagents

+10.3%

+22.1%

Instruments

694

▲17

+25

▲2.5%

+3.8%

CDMO

3,183

▲1,548

▲121

▲32.7%

▲3.7%

Gene [2]

1,144

+26

▲50

Therapy

+2.3%

▲4.2%

Gross

22,025

▲1,470

+2,338

profit

▲6.3%

+11.9%

Operating

10,870

▲3,234

+2,228

profit

▲22.9%

+25.8

R&D

3,853

+1,193

+122

+44.9%

+3.3%

(Explanation of Y/Y changes)

  • Reagents: Grew in sales of COVID testing-related reagents, while sales of general research reagents remained firm.
  • Instruments: Sales of PCR equipment and single-cellanalysis equipment remained the same level as the previous fiscal year.
  • CDMO: Lower sales related to COVID vaccines and large-scale genome analysis projects
  • Gene therapy: Sales of GMP grade reagents increased.
  • Operating profit: Gross profit declined due to product mix and other factors. Operating profit decreased due to aggressive investment in R&D, etc.

2

[1] Including in vitro diagnostics

[2] Sales of GMP grade reagents, were reclassified from "Reagents" to "Gene Therapy" from the fiscal year under review.

The 2nd Quarter; Operating Profit

Y/Y

Previous forecast

disclosed on May 12, 2022

FY2021

FY2021

FY2022

141

Previous

86

Forecast

22/ 3期

前期回初予想

売

Sales

売

Sales

▲5

+25

上 Sales

上 Sales

売

売上差

売

売上差

profit上

profit

総Composition

総Composition

総

▲21

上

▲9

総Composition

Composition

利 構成差

利 構成差

益

益

利

利

Gross益

Gross

Exchange

+12

益

+7

Exchange

為替差

為替差

R&D

▲11

R&D

▲1

研究開発費

研究開発費

Personnel*

▲4

Personnel*

▲2

⼈件費※

⼈件費※

▲1

Other

Other

+3

その他経費

その他経費

FY2023

108

FY2023

108

23/ 期

23/03期

100

120

140

億円)

80

100 (100 million yen)

(100 million yen)

3 * Excluding R&D personnel expenses

The 2nd Quarter; Reagents

Actual net sales

Sales performance by region

(100 million yen)

300

249

275

FY2022

COVID

22/03期

249

138

為替

+15

General research

Exchange

120

⽇本

+27

200

Japan

⽶国

+8

U.S.

China

▲6

114

129

137

中国

欧州

100

40

129

Europe

▲19

韓国

0

89

Korea

India印度

0

FY2023

275

0

23/03期

20/03FY2020期 21/03FY2021期 22/FY20223期 23/FY2023期

240

300

(100 million yen)

4

Graphs are displayed reflecting the reclassification of sales of GMP grade reagents, etc.

The 2nd Quarter; CDMO

Actual net sales

(100 million yen)

50

47

Others

3

Gene analysis & testing

40

Regenerative medicine

15

356

313

30

11

222

28

8

20

20

8

17

10 11

0

20/03FY2020期 21/03FY2021期 22/03FY2022期 23/03FY2023期

5

Regenerative medicine

  • Sales decreased due to a decline in COVID vaccine- related contracts, despite robust sales of vector production, cell processing, and quality testing

Gene analysis and testing

  • Decreased in sales due to the impact of the completion of large-scale genome analysis projects such as human whole genome analysis.

Contents

  • Consolidated Financial Results for the Second Quarter Ended September 30, 2022
  • Consolidated Financial Forecast for the Year Ending March 31, 2023
  • Business Progress and Future Measures

6

Consolidated Financial Forecast for FY2023

(for the Year Ending March 31, 2023)

FY2023

Y/Y

Comparison

Full-year

with May 12

(millions yen)

forecast

Net sales

77,800

+10,100

+22,500

+14.9%

+40.7%

[1]

65,106

+12,626

+24,095

Reagents

+24.1%

+58.8%

Instruments

1,716

+197

+244

+13.0%

+16.6%

CDMO

8,356

▲3,070

▲1,855

▲26.9%

▲18.2%

Gene [2]

2,621

+346

+15

Therapy

+15.2%

+0.6%

Gross

43,731

▲5,480

+5,875

profit

▲11.1%

+15.5%

Operating

19,000

▲9,902

+4,000

profit

▲34.3%

+26.7

R&D

8,713

+2,604

+893

+42.6%

+11.4%

(Explanation of Y/Y changes)

  • Reagents: Significant growth in COVID testing-related reagents, steady growth in general research reagents
  • Instruments: PCR equipment sales down slightly, single-cell analysis equipment sales up
  • CDMO: COVID vaccine-related contract and large-scale genome analysis project-related contract sales decreased
  • Gene Therapy: Sales of GMP grade reagents increased
  • Operating profit: Gross profit decreased due to product mix and other factors. Operating income decreased due to aggressive investment in R&D, etc.

7

[1] Including in vitro diagnostics

[2] Sales of GMP grade reagents, were reclassified from "Reagents" to "Gene Therapy" from the fiscal year under review.

Full-year Forecast; Operating Profit

Y/Y

Previous forecast

disclosed on May 12, 2022

Gross profit

FY2022

289

Previous

150

forecast

期初予想

22/03期

5⽉12⽇予想

Sales

+42

Sales

+149

売上差

profit上

売上差

構成差

構成差

売

Composition

▲121

総Composition

▲110

利

Gross

Exchange

+24

益

+20

Exchange

為替差

為替差

R&D

▲26

R&D

▲8

研究開発費

研究開発費

▲11

▲9

Personnel*⼈件費※

Personnel*⼈件費※

Other

▲7

Other

▲1

その他経費

その他経費

FY2023

FY2023

190

190

23/03期

23/03期

forecast

forecast

予想

予想

100

200

300

(億円)

100

200

300 (億円)

(100 million yen)

(100 million yen)

8 * Excluding R&D personnel expenses

Full-year Forecast;

Reagents and Instruments

Actual Net Sales and Forecast

Reagents

(100 million yen)

MMP2023

651

COVID: In addition to PCR diagnostic reagents,

sales are expected to increase significantly due

600

COVID

524

342

to a significant contribution from antigen

General research

testing kits.

400

256

General research: Overall sales are forecast to

339

283

increase Y/Y, despite regional differences and

236

225

130

308

the impact of foreign exchange rates. Forecast

200

236

209

268

to achieve the final-year targets of the

medium-term management plan FY2023

0

(MMP2023).

実績

中計

実績

実績

中計 予想

Instruments

Actual

MMP2023 Actual

Actual

MMP2023

Forecast

(100 million yen)

22

Sales of PCR equipment was consistent with

20

17

15

17

12

the preceding period due to COVID testing-

11

related demand and other factors. Expected to

10

increase overall sales due to growth in single-

cell analysis-related equipment.

Targets for the final year of the MMP2023 are

0

Actual

MMP2023 Actual

Actual

MMP2023中計

Forecast

not expected to be achieved.

実績

中計

実績

実績

予想

20/03期

21/03期

22/ 3

23/

期

FY2020

FY2021

FY2022期

FY2023

9

Graphs are displayed reflecting the reclassification of sales of GMP grade reagents, etc.

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