Sysmex : Notice of Changes in Representative Directors

February 12, 2026 Sysmex Corporation

Sysmex Corporation (HQ: Kobe, Japan; President: Kaoru Asano) announces that it has resolved, at a meeting of the Board of Directors held on February 12, 2026, to change the representative directors as stated below.

1. Reasons for Change

   To further strengthen management structure in order to enhance corporate value.

2. Newly Appointed Representative Director

   Name	New title	Current title
   Iwane Matsui	President (Representative Director)	Member of the Managing Board and Senior Executive Officer Senior Managing Director

3. Representative Director to Resign

   Name	New title	Current title
   Kaoru Asano	Member of the Managing Board	President (Representative Director)

   Kaoru Asano is scheduled to resign from the Member of the Managing Board at the Ordinary General Meeting of Shareholders to be held in June 2026 and subsequently serve as Senior Executive Advisor.

   There are no changes to Hisashi Ietsugu's current position as Chairperson and Group CEO.

4. Career summary of new representative director As per Exhibit.

5. Effective Date of Transfer (Scheduled) April 1, 2026

Name: Iwane Matsui Date of Birth: January 1, 1961

Education: Kobe University, Bachelor of Faculty of Law Career:

Public Offices: Vice President at Japan Association of Clinical Reagents Industries Shareholding: 14,700 shares (as of December 31, 2025)