Philogen SpaMIL: PHIL

Corporate Financial Calendar 2025 (ENG)

· Issued by Philogen Spa

PRESS RELEASE

PHILOGEN S.p.A.

2025 CALENDAR OF CORPORATE EVENTS

Siena (Italy), 30 January 2025 - Philogen S.p.A. (the "Company" or "Philogen") discloses, pursuant to art. 2.6.2 paragraph 1 of the Regulations for the Markets organised and managed by Borsa Italiana S.p.A., the calendar of corporate events relating to the financial year 2025.

  • March 27, 2025

Board of Directors' Meeting for the approval of the Draft Financial Statements and the 2024 Consolidated Financial Statements

  • April 29, 2025

Shareholders' Meeting for the approval of the 2024 Financial Statements

  • May 6, 2025

Board of Directors' meeting for the approval of the press release containing a quarterly report with selected information indicative of the performance of the business relating to the first quarter of 2025 (net financial position and progress of the main trials of NidlegyTM and Fibromun)

  • September 23, 2025

Board of Directors' Meeting for the approval of the Half-Year Financial Report as at 30 June 2025

  • November 11, 2025

Board of Directors' meeting for the approval of the press release containing a quarterly report with selected information indicative of the performance of the business relating to the third quarter of 2025 (net financial position and progress of the main trials of NidlegyTM and Fibromun)

Philogen will promptly communicate any changes with respect to the dates communicated. The calendar of corporate events is also available on the Company's website www.philogen.comin the "investors/financial-calendar" section

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PRESS RELEASE

Description of the Philogen Group

Philogen is an Italian-Swiss company active in the biotechnology sector, specialized in the research and development of pharmaceutical products for the treatment of diseases with a high lethality rate. The Group mainly discovers and develops targeted anticancer drugs, exploiting high-affinity ligands for tumor markers (also called tumor antigens). These ligands - human monoclonal antibodies or small organic molecules - are identified through Antibody Phage Display Libraries and DNA-Encoded Chemical Libraries technologies.

The Group's main therapeutic strategy for the treatment of these diseases is represented by the so-called tumor targeting. This approach is based on the use of ligands capable of selectively conveying very powerful therapeutic active ingredients (such as, for example, pro-inflammatory cytokines) to the tumor mass, sparing healthy tissues. Over the years, Philogen has mainly developed ligands based on monoclonal antibodies, specific for antigens expressed in blood vessels associated with tumors, but not expressed in blood vessels associated with healthy tissues. These antigens are usually more abundant and more stable than those expressed directly on the surface of cancer cells. This approach, the so-called vascular targeting, is used for most of the projects pursued by the Group.

The Group's goal is to generate, develop and commercialize innovative products for the treatment of diseases for which medical science has not yet identified satisfactory therapies. This is achieved by leveraging (i) proprietary technologies for the isolation of ligands that react with antigens present in certain diseases, (ii) experience in the development of products targeting tissues affected by the disease, (iii) experience in the production and development of drugs and (iv) the broad portfolio of patents and intellectual property rights.

Although the Group's drugs are mainly oncological applications, the targeting approach is potentially applicable to other diseases as well, such as some chronic inflammatory diseases.

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FOR FURTHER INFORMATION:

Philogen - Investor Relations

IR@philogen.com- Emanuele Puca | Investor Relations

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