30 September 2026
Coiled Therapeutics plc
("Coiled Therapeutics" or the "Company")
Participation in The Small Cap Showcase
Coiled Therapeutics (AIM: COIL) (OTCQB: COTXF), the clinical-stage precision oncology company developing differentiated small molecule therapies for genetically defined cancers, announces that members of its executive management team will participate in The Small Cap Showcase on Thursday 1 October 2026 in New York City.
Dr Sotirios Stergiopoulos, Chairman and Stephen West, Non-Executive Director will present at 11:00 a.m. ET (4 p.m. BST), providing an overview of its business strategy, growth opportunities, recent developments and outlook. Management will also participate in one-on-one meetings with pre-qualified investors throughout the day.
A live webcast of the Company's presentation will be available at: https://www.webcaster5.com/Webcast/Page/3173/54585
The Small Cap Showcase is an investor-focused conference connecting executive management teams from approximately 12 micro- and small-cap public companies with institutional and other qualified investors. The event is designed to provide investors with meaningful access to differentiated small-cap investment opportunities through company presentations, one-on-one meetings and networking throughout the day.
For more information about The Small Cap Showcase, please visit www.smallcapshowcase.com.
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Enquiries:
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Coiled Therapeutics plc Sotirios Stergiopoulos (Chairman) Sridhar Vempati (CEO) |
Via Burson Buchanan |
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SP Angel Corporate Finance LLP (Nominated Adviser & Joint Broker) David Hignell / Adam Cowl / Devik Mehta (Corporate Finance) Vadim Alexandre / Rob Rees (Corporate Broking) |
+44 (0)20 3470 0470 |
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Shore Capital Stockbrokers Limited (Joint Broker) David Coaten / Sophie Collins |
+44 (0)20 7408 4090 |
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CPS Capital Group Pty Ltd (Joint Broker) Jason Peterson / David Valentino |
+61 (0)8 9223 2222 |
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Burson Buchanan (Public Relations) |
+44 (0)20 7466 5000 |
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Henry Harrison Topham / Jamie Hooper / Toto Berger |
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Harbor Access (US Investor Relations) |
+1 475 477 9404 |
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Matt Kelly / Jonathan Paterson |
About Coiled Therapeutics plc
Coiled Therapeutics (AIM: COIL) (OTCQB: COTXF) is an AIM-listed, clinical-stage precision oncology company advancing first-in-class small molecule therapies targeting validated cancer dependencies. Its lead programme, AO-252, is a novel TACC3 inhibitor currently being evaluated in an ongoing Phase I clinical trial in the U.S. (ClinicalTrials.gov ID: NCT06136884). The Company's clinical development strategy focuses on generating evidence in selected tumour types, including ovarian and prostate cancer, to support potential pharmaceutical partnerships. Its broader pipeline includes a STAT-6 siRNA programme for immunology indications.
About AO-252
AO-252 is a first-in-class, orally administered, brain-penetrant small molecule designed to selectively inhibit Transforming Acidic Coiled-Coil containing protein 3 (TACC3). TACC3 has emerged as a validated cancer dependency across multiple aggressive solid tumours and is largely dispensable in normal adult cells, supporting the potential for a broad therapeutic window.
By disrupting TACC3-driven protein interactions, AO-252 induces mitotic and replication stress, impairs DNA damage repair and promotes cancer cell death. Its ability to cross the blood-brain barrier is a key differentiator, supporting its potential to treat both primary brain tumours and brain metastases.
The Company is currently enrolling patients in dose-escalation cohorts evaluating the new lipid-based softgel formulation of AO-252. Phase I/II dose-expansion cohorts in ovarian and prostate cancer are planned to follow once the optimal dose has been established.
For more information, please visit: www.coiledplc.com and follow us on LinkedIn.