Proteome Sciences PLC ("the Company")
Notifiable Interest
A form TR-1 containing the following information has been received by the
Company.
TR-1 notification of major interests in shares
1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached:
Proteome Sciences PLC
2. Reason for the notification
An acquisition or disposal of voting rights
3. Full name of person(s) subject to the notification obligation:
Crédit Agricole Cheuvreux International Limited
4. Full name of shareholder(s) (if different from 3):
N/A
5. Date of the transaction (and date on which the threshold is crossed or
reached if different):
16/11/07
6. Date on which issuer notified:
20/11/07
7. Threshold(s) that is/are crossed or reached:
Holding after transaction went through percentage threshold
8. Notified details:
A: Voting rights attached to shares
Class/type of Situation previous to Resulting situation after the triggering
shares Triggering transaction transaction
if possible Notification required under DTR transitional
using ISIN provision 7
CODE
Number of Shares Number of Number of Number of voting % of voting
Voting shares rights rights
Rights
Direct Direct Indirect Direct Indirect
GB0003104196 10,530,481 10,530,481 10,480,481 10,480,481 7.97%
B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting rights that may % of
financial date Conversion be acquired if the instrument is voting
instrument Period/ Date exercised/ converted rights
Total (A+B)
Number of voting rights % of voting rights
10,480,481 7.97%
9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:
SAS Rue La Boétie
Crédit Agricole SA
Calyon SA
Crédit Agricole Cheuvreux SA 10,480,481 7.97%
10. Name of the Proxy holder:
N/A
11. Number of voting rights proxy holder will cease to hold:
N/A
12. Date on which proxy holder will cease to hold voting rights:
N/A
13. Additional information:
N/A
14. Contact name:
Karen Browne
15. Contact telephone number:
020 7214 5282

