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NewAmsterdam Pharma to Present New Clinical and Preclinical Data at 93rd EAS Congress

Presentations include new data from BROADWAY and TANDEM Phase 3 clinical trials, demonstrating obicetrapib’s impact on key lipid and lipoprotein biomarkers

Newamsterdam Pharma Company N.v.April 30, 20255
NewAmsterdam Pharma to Present New Clinical and Preclinical Data at 93rd EAS Congress

About this update from Newamsterdam Pharma Company N.v.

Presentations include new data from BROADWAY and TANDEM Phase 3 clinical trials, demonstrating obicetrapib’s impact on key lipid and lipoprotein biomarkers NAARDEN, the Netherlands and MIAMI , April 30, 2025 (GLOBE NEWSWIRE) -- NewAmsterdam Pharma Company N.V. (Nasdaq: NAMS or “NewAmsterdam” or the “Company”), a late-stage, clinical biopharmaceutical company developing oral, non-statin medicines for patients at risk of cardiovascular disease (“CVD”) with elevated low-density lipoprotein cholesterol (“LDL-C”), for whom existing therapies are not sufficiently effective or well-tolerated, today announced it will present new clinical and preclinical data highlighting the potential for obicetrapib as a novel, oral, low-dose therapy for hypercholesterolemia, at the European Atherosclerosis Society (EAS) 93rd Congress , taking place on May 4-7, 2025 in Glasgow, UK . Late-breaker oral presentation details are as follows: Title: Fixed-Dose Combination of Obicetrapib and Ezetimibe for LDL-C Reduction: A Phase 3 Randomized Trial Session Name : Late Breaker Session: Clinical Oral Presentation Date and Time: Wednesday, May 5, 2025 , 12:00-12:15 PM BST ( 7:00-7:15 AM ET ) Location: William Harvey Hall Title: Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk Session Name : Late Breaker Session: Clinical Oral Presentation Date and Time: Wednesday, May 5, 2025 , 12:15-12:30 PM BST ( 7:15-7:30 AM ET ) Location: Will Harvey Hall Additional session details are as follows: Title: Obicetrapib Reduces Atherosclerosis and Vascular Inflammation, Mainly by Reducing Non-HDL Cholesterol, Improves Lesion Stability and Adds to the Beneficial Effects of Ezetimibe Session Name : SaaG Session: Emerging Lipid-Lowering Strategies: Mechanisms, Pre-clinical Studies and Outcomes Presentation Date and Time: Monday, May 5, 2025 , 1:58-2:05 PM BST ( 8:58-9:05 AM ET ) Location: Station 7 Title: Obicetrapib Alone and in Combination with Ezetimibe Increases Reverse Cholesterol Transport and Does Not Affect VLDL Production Session Name : SaaG Session: Emerging Lipid-Lowering Strategies: Mechanisms, Pre-clinical Studies and Outcomes Presentation Date and Time: Monday, May 5, 2025 , 2:05-2:12 PM BST ( 9:05-9:12 AM ET ) Location: Station 7 Title: Low-Dose Obicetrapib Significantly Increases Concentrations of Lipophilic Antioxidants, ApoE, and S1P in HDL Subfractions Session Name : SaaG Session: Lipid Lowering Therapies and Advances in Vascular Therapeutics Presentation Date and Time: Monday, May 5, 2025 , 2:19-2:26 PM BST ( 9:19-9:26 AM ET ) Location: Station 4 Title: Obicetrapib Significantly Increases Plasma and High-Density Lipoprotein (HDL) Levels of Lipophilic Antioxidants Session Name : SaaG Session: Lipoprotein Dynamics: HDL to Remnants Presentation Date and Time: Monday, May 5, 2025 , 3:17-3:24 PM BST ( 10:17-10:24 AM ET ) Location: Station 3 Title: Efficacy and Safety of Combination Obicetrapib with Moderate-Dose Statins Session Name : Poster Networking Sessions Presentation Date and Time: Monday, May 5 & Tuesday, May 6, 2025 , 5:20 - 6:50 PM BST ( 12:17-1:24 PM ET ) Location: Poster Board #246, Exhibition Hall Title: Safety and Efficacy of Cholesteryl Ester Transfer Protein Inhibition: From Genetics to Outcome Trials Session Name : Workshop: New risk factors for atherosclerotic disease Presentation Date and Time: Wednesday, May 7, 2025 , 12:20 -12:30 PM BST ( 7:17-8:24 AM ET ) Location: James Black Hall About NewAmsterdam NewAmsterdam Pharma (Nasdaq: NAMS) is a late-stage biopharmaceutical company whose mission is to improve patient care in populations with metabolic diseases where currently approved therapies have not been adequate or well tolerated. We seek to fill a significant unmet need for a safe, well-tolerated and convenient LDL-lowering therapy. In multiple phase 3 trials, NewAmsterdam is investigating obicetrapib, an oral, low-dose and once-daily CETP inhibitor, alone or as a fixed-dose combination with ezetimibe, as LDL-C lowering therapies to be used as an adjunct to statin therapy for patients at risk of CVD with elevated LDL-C, for whom existing therapies are not sufficiently effective or well tolerated. Company Contact Matthew Philippe P: 1-917-882-7512 [email protected] Media Contact Spectrum Science on behalf of NewAmsterdam Jaryd Leady P: 1-856-803-7855 [email protected] Investor Contact Precision AQ on behalf of NewAmsterdam Austin Murtagh P: 1-212-698-8696 [email protected] Source: NewAmsterdam Pharma N.V.

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