MEIRAGTX HOLDINGS PLC : COMPANY ANNOUNCEMENT : AMENDMENT NOTICE

About this update from Meiragtx Holdings Plc

MeiraGTx Holdings plc C/O Walkers Corporate Limited 190 Elgin Avenue George Town Grand Cayman KY1-9008 Cayman Islands (the " Issuer ") Fourth Floor, Pavilion East Cricket Square, 205 Elgin Avenue Grand Cayman Cayman Islands (the " Exchange ") For Immediate Release 20 April 2026 Dear Addressee The Issuer refers to the admission to listing on the Exchange of up to $100,000,000 fluctuating rate senior secured loan notes (the " Notes ") under an Amended and Restated Note Purchase Agreement and Guaranty dated 19 December 2022 (as amended) (" Note Purchase Agreement ") as described in the listing document dated 25 January 2023. The Issuer hereby announces that, pursuant to the terms of a Deed of Amendment to the Note Purchase Agreement, the Notes will be amended in order that the maturity date of the Notes be extended from 2 August 2026 to 2 May 2027. For further information in relation to the above announcement please contact: Samuel Buchan Walkers Tel: +1 345 9364624 Email: [email protected]

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