Kane Biotech Inc.TSXV: KNE

Kane Biotech to Present Clinical Data and Showcase revyve® Product Line at SAWC Fall 2026

· Issued by Kane Biotech Inc. via GlobeNewswire

WINNIPEG, Manitoba, Oct. 07, 2026 (GLOBE NEWSWIRE) -- Kane Biotech Inc. (TSX-V:KNE) (the “Company”, “Kane” or “Kane Biotech”), a biotechnology company commercializing and developing technologies and products that address microbial biofilms, today announced that it will attend the Symposium on Advanced Wound Care (“SAWC”) Fall 2026, taking place October 15–18, 2026, in Las Vegas, Nevada.

On Saturday, October 17, 2026, from 6:15 p.m. to 7:30 p.m. PDT, Dr. Robert Huizinga will present three scientific posters at SAWC Fall 2026 describing the clinical and health-economic findings associated with revyve®. The presentations address the modeled economic impact of moving chronic wounds toward healing trajectories, compatibility with hypochlorous acid irrigation and standard wound-care practices, and the relationship between changes in tissue oxygenation and wound-area reduction. The posters are authored by a multidisciplinary team of clinical and scientific collaborators, including Kane Biotech.

Kane will also host Booth #544 in the SAWC Fall exhibit hall, where it will showcase its revyve product line and engage with clinicians, researchers and other wound-care professionals. Kane plans to meet with its existing distributors and prospective new distributors to discuss opportunities to expand product awareness and commercial reach in the United States and other markets.

U.S. FDA 510(k) cleared and Health Canada approved revyve Antimicrobial Wound Gel and revyve Antimicrobial Wound Gel Spray

“As adoption of revyve continues to grow, SAWC Fall provides an important venue to connect directly with clinicians and distribution partners across the wound-care community,” said S. Kay Watkins Weaver, Vice President, Commercial Operations, U.S. at Kane Biotech. “We look forward to discussing our latest clinical findings, showcasing the revyve platform and exploring opportunities to expand access to these products in both existing and new markets.”

SAWC Fall is a four-day, multidisciplinary educational conference that brings together the wound-care community to advance healing, strengthen collaboration and improve patient care. The 2026 program features practical education addressing chronic wounds, limb salvage, pressure-injury prevention, mobile wound care, reimbursement, compliance and emerging technologies. For more information, visit the SAWC Fall conference website.

Kane’s revyve portfolio currently includes U.S. FDA 510(k) cleared revyve Antimicrobial Wound Gel, revyve Antimicrobial Wound Gel Spray and revyve Antimicrobial Skin and Wound Cleanser. The wound gel and wound gel spray are also approved by Health Canada. Kane is ISO 13485:2016 certified under the Medical Device Single Audit Program.

About Kane Biotech Inc. (TSX-V:KNE)

Kane Biotech is commercializing and developing novel wound care treatments that disrupt biofilms and transform healing outcomes. Biofilms are one of the main contributors to antibiotic resistance in wounds, resulting in serious clinical outcomes and significant cost. revyve addresses both biofilms and wound bacteria. revyve Antimicrobial Wound Gel, revyve Antimicrobial Wound Gel Spray and revyve Antimicrobial Skin and Wound Cleanser are all U.S. FDA 510(k) cleared. revyve Antimicrobial Wound Gel and revyve Antimicrobial Wound Gel Spray are also Health Canada approved. To learn more, visit revyvegel.com or revyvegel.ca.

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Website & Corporate Presentation:

kanebiotech.com

Disrupting Biofilms to Save Limbs and Transform Wound Care

For more information:

Dr. Robert HuizingaRay Dupuis
Interim CEOChief Financial Officer
Kane Biotech Inc.Kane Biotech Inc.
rhuizinga@kanebiotech.comrdupuis@kanebiotech.com
(780) 970-1100(204) 298-2200
  

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Caution Regarding Forward-Looking Information

This press release contains certain statements regarding Kane Biotech Inc. that constitute forward-looking information under applicable securities law. These statements reflect management’s current beliefs and are based on information currently available to management. Certain material factors or assumptions are applied in making forward-looking statements, and actual results may differ materially from those expressed or implied in such statements. These risks and uncertainties include, but are not limited to, risks relating to the Company’s: (a) financial condition, including lack of significant revenues to date and reliance on equity and other financing; (b) business, including its early stage of development, government regulation, market acceptance for its products, rapid technological change and dependence on key personnel; (c) intellectual property including the ability of the Company to protect its intellectual property and dependence on its strategic partners; and (d) capital structure, including its lack of dividends on its common shares, volatility of the market price of its common shares and public company costs. Further information about these and other risks and uncertainties can be found in the disclosure documents filed by the Company with applicable securities regulatory authorities, available at www.sedarplus.ca. The Company cautions that the foregoing list of factors that may affect future results is not exhaustive.

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/1e960731-845e-4b9d-9e81-28fcac23fc86


Attached document

Contents
  1. Disrupting Biofilms to Save Limbs and Transform Wound Care · page 1
  2. Dr. Robert Huizinga · page 1
  3. Forward-Looking Statements · page 2
  4. A Preventable Healthcare Crisis in the US ($USD) · page 3
  5. The human and economic burden of chronic wounds is escalating · page 3
  6. >$100K USD · page 3
  7. A Preventable Healthcare Crisis in Canada ($CAD) · page 4
  8. * Excludes outpatient care, rehabilitation, prosthetics, and long-term support. · page 4
  9. $47,000 · page 4
  10. $750M · page 4
  11. >$12 Billion · page 4
  12. 3-5 Times · page 4
  13. Biofilms: The 1,000X Problem · page 5
  14. The Hidden Culprit · page 5
  15. Protected Bacteria needed. · page 5
  16. What Is A Biofilm? · page 5
  17. THE TREATMENT GAP · page 5
  18. Why Current Solutions Fail · page 6
  19. Surgical Debridement · page 6
  20. Antibiotic Debridement · page 6
  21. Current Hydrogels · page 6
  22. Advanced Dressings · page 6
  23. Oo · page 6
  24. Antibiotic Treatments · page 6
  25. $423M - $493M US Market Opportunity · page 7
  26. $350M · page 7
  27. Chronic Wounds · page 7
  28. Care Setting Mix: · page 7
  29. $80-150M · page 7
  30. Inpatient Burn/Wound · page 7
  31. Market Growth Drivers · page 7
  32. Diabetes Epidemic · page 7
  33. Surgical Volume · page 7
  34. Antibiotic Crisis · page 7
  35. ® revyve : Three Mechanisms in One · page 8
  36. Biofilm Disruption · page 8
  37. Antimicrobial Killing · page 8
  38. THE REVYVE® ADVANTAGE: COMPLETE CARE · page 8
  39. Healing Support · page 8
  40. THE REVYVE ® ADVANTAGE: COMPLETE CARE · page 8
  41. 7-Day Biofilm Killing Power · page 9
  42. Sustained activity against antibiotic-resistant pathogens without regrowth · page 9
  43. Effective vs. Antibiotic-Resistant Strains (MRSA) · page 9
  44. Gram-Positive · page 9
  45. Real World Case Series – Multiple Centers · page 10
  46. Consistent outcomes across 9 leading wound care centers in the US and Canada · page 10
  47. Participating Clinical Centers · page 10
  48. Case Series Design · page 10
  49. PRELIMINARY FINDINGS · page 10
  50. Peer-reviewed publication in preparation · page 10
  51. From Non-Healing to Healed · page 11
  52. Case Study 1: 52-Year-Old Male with Diabetic Foot Ulcer · page 11
  53. Case Study 2: 62-Year-Old Female with Chronic Venous Leg Ulcer · page 11
  54. Pain: 10 -> 0 (Week 6) · page 11
  55. Product Portfolio · page 12
  56. Two FDA-cleared formats covering the full spectrum of wound care needs · page 12
  57. Antimicrobial Wound Gel ###### Tube Format (85g/3 oz) · page 12
  58. FDA 510(k) Cleared · page 12
  59. Target Markets · page 12
  60. Antimicrobial Wound Spray ###### Non-Aerosol Spray (5 oz) · page 12
  61. FDA 510(k) Cleared · page 12
  62. Target Markets · page 12
  63. Competitive Differentiation · page 12
  64. vs. Antibiotic Ointments · page 12
  65. vs. Advanced Biologics · page 12
  66. Transforming Wound Care · page 13
  67. Preventing amputations. Creating shareholder value. · page 13
  68. 130,000 · page 13
  69. AMPUTATIONS / YEAR · page 13
  70. The Solution · page 13
  71. revyve® · page 13
  72. The Market · page 13
  73. $423M+ USD · page 13
  74. US ADDRESSABLE MARKET · page 13
  75. The Inflection · page 13
  76. NOW · page 13
  77. EXECUTION PHASE · page 13
  78. The Investment · page 13
  79. VALUE · page 13
  80. Three Paths to Value Creation · page 13
  81. 1. Organic Growth · page 13
  82. 2. Strategic Partnership · page 13
  83. 3. Acquisition · page 13
  84. Partner With Us to Transform Wound Care · page 14
  85. Dr. Robert Huizinga, PhD, RN · page 14
  86. Ray Dupuis, CPA, MBA · page 14
  87. KNE · page 14
  88. KNBIF · page 14

Page 1

Introduction Presentation | May 2026

Disrupting Biofilms to Save Limbs and Transform Wound Care

"Every 4 minutes, a diabetic patient in America loses a limb."

Dr. Robert Huizinga

Interim Chief Executive Officer

rhuizinga@kanebiotech.com

www.kanebiotech.com

TSX-V: KNE

OTC: KNBIF

CONFIDENTIAL | © 2026 Kane Biotech Inc.

Page 2

LEGAL DISCLAIMER

Forward-Looking Statements

This presentation contains forward-looking statements, which are made pursuant to the safe harbour provisions of the U.S. Securities Litigation Reform Act of 1995. Forward-looking statements involve known and unknown risks and uncertainties which could cause the Company's actual results to differ materially from those in the forward-looking statements.

Such risks and uncertainties include, but are not limited to, the availability of funds and resources to pursue R&D activities, the successful and timely completion of clinical studies, the ability of the Company to take advantage of business opportunities in its specific industry, and uncertainties related to the regulatory process and general changes in economic conditions.

Introductions should consult the Company's ongoing filings which are available on SEDAR for additional information on risks and uncertainties relating to forward-looking statements. Introductions are cautioned not to rely on these forward-looking statements nor does the Company undertake to update or revise any these forward-looking statements contained herein.

Kane Biotech Introduction Presentation | May 2026

Page 3

THE PROBLEM

A Preventable Healthcare Crisis in the US ($USD)

The human and economic burden of chronic wounds is escalating

130,000

Amputations per year among diabetic patients

One every 4 minutes

10.5M

Medicare beneficiaries suffering from chronic wounds

Non-healing wound population

700,000

Burn-related insurance claims annually

Includes 29,000 hospital admissions

>$100K USD

Average cost per burn treatment Massive economic burden

These aren't just statistics. They represent a systemic failure to treat the root cause of chronic infections.

SOURCE: CMS DATA / CDC

Malone, M., et al. (2017). The prevalence of biofilms in chronic wounds. Journal of Wound Care, 26(1):20-25; James GA, et al. (2008) Wound Repair Regen 16:37-44

Page 4

A Preventable Healthcare Crisis in Canada ($CAD)

* Excludes outpatient care, rehabilitation, prosthetics, and long-term support.

Canada

$47,000

Average cost per hospitalization for a diabetic amputation

$750M

Annual hospitalization costs for diabetes-related lower limb complications (including amputations, ulcers, gangrene, infections)

>$12 Billion

Estimated annual direct spending on total wound care in Canada Massive economic burden

3-5 Times

First Nations people in Canada face significantly higher rates of diabetesrelated amputations—often 3–5 times higher than others, or up to 18 times higher in specific regions like Manitoba

These aren't just statistics. They represent our inability to treat the root cause of chronic infections.

• Canadian Institute for Health Information (CIHI), 2024. Equity in diabetes care: A focus on lower limb amputation. https://www.cihi.ca/en/equity-in-diabetes-care-a-focus-on-lower-limb-amputation

• Queen D, Botros M. 2024. The true cost of wounds for Canadians. Wound Care Canada. 22(1): 16-20. DOI: 10.56885/NXMW2913

• Shah BR, Frymire E, Jacklin K, Jones CR, Khan S, Slater M, Walker JD, Green ME. Peripheral arterial disease in Ontario First Nations people with diabetes: a longitudinal population-based cohort study. CMAJ Open. 2019 Dec 10;7(4):E700-E705. doi: 10.9778/cmajo.20190162. PMID: 31822500; PMCID: PMC7015673.

Page 5

THE SCIENCE

Biofilms: The 1,000X Problem

Why standard treatments fail to heal chronic wounds

The Hidden Culprit

70%

of burn wounds contain biofilm layers

80%

of chronic wounds have established biofilms

1,000X

more resistant to antibiotics than regular bacteria

Physical or chemical disruption of biofilm before bacterial killing is needed.

Protected Bacteria needed.

What Is A Biofilm?

A protective microscopic matrix created by bacteria to defend themselves

Reduces metabolic activity (making bacteria "invisible" to immune system)

Shields bacteria from antibiotics, disinfectants, and host defenses

BIOFILM BARRIER DIAGRAM

Protected Bacteria

THE TREATMENT GAP

Whether from diabetes, burns, or surgery, effective wound care MUST treat both bacteria AND biofilms. Current products often don't.

Malone, M., et al. (2017). The prevalence of biofilms in chronic wounds. Journal of Wound Care, 26(1):20-25

Page 6

COMPETITIVE LANDSCAPE

Why Current Solutions Fail

Existing standards of care leave critical gaps in treatment: revyve® has the potential to be the standard of care.

Surgical Debridement

Antibiotic Debridement

Painful and traumatic procedure

Expensive, requires clinic visit

Biofilms reform within 24 hours

Removes necrotic tissue

Current Hydrogels

No biofilm disruption capability

Limited antimicrobial duration

Requires daily dressing changes

Maintains moisture balance

Advanced Dressings

Extremely high cost ($1,000+)

Limited reimbursement access

Do not actively disrupt biofilms

Creates supportive environment

Oo

Antibiotic Treatments

Poor penetration into biofilms

Drives antibiotic resistance

Systemic side effects & dosing issues

Only treats planktonic bacteria

The Gap in Standard of Care

No existing solution addresses: Biofilm Disruption + Sustained Antimicrobial + Ease of Use + Reimbursement

Page 7

THE OPPORTUNITY

$423M - $493M US Market Opportunity

Addressing massive unmet needs across multiple care settings

$350M

Chronic Wounds

Diabetic Foot Ulcers (DFUs)

Venous/Arterial Leg Ulcers

Pressure Ulcers

Care Setting Mix:

Outpatient Offices and Clinics (50%) Medicare Part B DME

Home Health/HOPD (30%)

VA/DOD (20%)

$80-150M

Inpatient Burn/Wound

450,000 Burn Patients/Year

Large Surface Area Wounds

Spray Format Advantage

Hospital Burn Centers & Trauma

Market Growth Drivers

Aging Population

10,000 boomers turn 65 daily

Diabetes Epidemic

37M Americans (11.6% of US population)

Surgical Volume

Rising post-op needs

Antibiotic Crisis

Need for non-antibiotic options

Page 8

® revyve : Three Mechanisms in One

The first technology to disrupt biofilms, kill bacteria, and support healing

Biofilm Disruption

Patented coactiv+ technology breaks down the biofilm matrix structure, exposing bacteria and reducing elevated protease activity.

Physical & chemical disruption

Antimicrobial Killing

Sustained killing of bacteria for up to 7 days without antibiotics. Effective against multi-species and resistant strains.

No antibiotic resistance

THE SOLUTION

THE REVYVE® ADVANTAGE: COMPLETE CARE

Disrupts biofilms + antimicrobial action

Fewer dressing changes (7-day duration)

Healing Support

Thermo-reversible gel supports autolytic debridement and maintains optimal moist wound environment for healing.

THE REVYVE ® ADVANTAGE: COMPLETE CARE

Easy application & removal

Works with existing dressing protocols Non-contact spray option reduces pain

Page 9

CLINICAL DATA

7-Day Biofilm Killing Power

Sustained activity against antibiotic-resistant pathogens without regrowth

>4 Log Reduction (99.99%+ Kill Rate)

✓

Sustained 7-Day Activity (No Regrowth)

#

Effective vs. Antibiotic-Resistant Strains (MRSA)

Gram-Positive

Escherichia coli

Mature 72h Biofilm Model

Staphylococcus aureus

Klebsiella pneumoniae

MRSA (Resistant Staph)

Antibiotic Resistant

Acinetobacter baumannii

Gram-Negative

Pseudomonas aeruginosa

Gram-Negative

Drake M., Visvalingam J., Sailer, M., Huizinga RB. (2025) Antimicrobial and Antibiofilm efficacies of a thermo-reversible Antimicrobial Wound Gel. Southern Region Burn Conference, Charleston, USA

Page 10

REAL WORLD VALIDATION

Real World Case Series – Multiple Centers

Consistent outcomes across 9 leading wound care centers in the US and Canada

Participating Clinical Centers

NY: Mount Sinai West

NC: Foot & Ankle Institute

CO: The WISH Clinic

NC: UNC (Chapel Hill) MO: St. Louis Foot & Ankle GA: Burn & Reconstructive

NC: Raleigh Foot & Ankle PA: Georgiades Surgical ON: Quinte Health Care

Case Series Design

Patient Mix: Diabetic Foot Ulcers, Venous Leg Ulcers, Surgical Wounds

PRELIMINARY FINDINGS

Q4 2025 – Q1 2026

High rate of conversion from non-healing to healing transition

Show more of the filing

Outcomes: Significant pain reduction & improved wound bed preparation

Feedback:** Positive clinician response on ease of application

Peer-reviewed publication in preparation

Page 11

CLINICAL PROOF

From Non-Healing to Healed

Disrupting biofilms changes outcomes for chronic wound patients

Case Study 1: 52-Year-Old Male with Diabetic Foot Ulcer

History: Multiple unsuccessful treatments prior to revyve®

Day 1 Baseline

Day 97

Near closure

Quinte Health Care

After Study End

FULLY HEALED

Case Study 2: 62-Year-Old Female with Chronic Venous Leg Ulcer

History: Recurrent since 2013. Comorbidities: Diabetes, Obesity, chronic phlebolymphedema

Week 1 Pain 10/10

Week 8 Pain 0/10

Pain: 10 -> 0 (Week 6)

Week 33 (Follow-up) SUSTAINED HEALING

Kane Biotech Inc., Data on File. R. Pointer et al. (2025) NSWOCC 2025; Bridge M, Ramirez G, Lantis II JC. (2025) Innovations in Wound Healing Symposium, Key West, USA

Page 12

PRODUCT PORTFOLIO

Product Portfolio

Two FDA-cleared formats covering the full spectrum of wound care needs

Antimicrobial Wound Gel ###### Tube Format (85g/3 oz)

Thermo-reversible: Liquid at cool temp, gel at body temp

Ease of Use: Easy to apply, stays in place, rinses off easily

Indications:** DFUs, leg ulcers, pressure ulcers, surgical incisions

FDA 510(k) Cleared

Health Canada Approved

Medicare Reimbursable

Target Markets

Outpatient Clinics • Podiatry • Long-Term Care • Home Health

Antimicrobial Wound Spray ###### Non-Aerosol Spray (5 oz)

Zero-Contact: Painless application for sensitive wounds

Technology:** Thick gel spray adheres to vertical surfaces

Indications:** Large surface burns, trauma, painful wounds

FDA 510(k) Cleared

Health Canada Approved

Patent Pending Delivery

Target Markets

Burn Centers • Trauma Centers • Emergency Dept • Inpatient

Competitive Differentiation

vs. Standard Hydrogels

Adds biofilm disruption + antimicrobial

+ 7-day duration (vs daily)

vs. Antibiotic Ointments

No resistance development

Penetrates biofilms effectively

vs. Advanced Biologics

Accessible pricing (vs $1,000+)

No specialized training needed

Page 13

INVESTMENT SUMMARY

Transforming Wound Care

Preventing amputations. Creating shareholder value.

The Problem

130,000

AMPUTATIONS / YEAR

Biofilms block healing

1,000X antibiotic resistance

The Solution

Current products fail

revyve®

DISRUPTS & KILLS

Breaks biofilm matrix

7-Day antimicrobial

The Market

FDA Cleared & Reimbursed

$423M+ USD

US ADDRESSABLE MARKET

- Aging & Diabetes growth

Resistance crisis tailwinds

Cost-saving solution

The Inflection

NOW

EXECUTION PHASE

Technical risk eliminated

Commercial launch 2026

Distribution imminent

The Investment

VALUE

ASYMMETRIC UPSIDE

De-risked asset

Undervalued potential

Near-term catalysts

Three Paths to Value Creation

1. Organic Growth

Execute 2026 commercial plan to reach break-even in 2027.

2. Strategic Partnership

Leverage IP for international licensing deals to generate non-dilutive capital.

3. Acquisition

Attractive target for med-tech leaders seeking wound care innovation & antibiotic alternatives.

"We are building a company, not just running a science project. We will be accountable to these milestones. We will communicate transparently. And we will create value for shareholders who believe in this mission."

Dr. Robert Huizinga

Page 14

LET'S CONNECT

Partner With Us to Transform Wound Care

Join us in preventing amputations and creating shareholder value

Dr. Robert Huizinga, PhD, RN

Interim Chief Executive Officer

rhuizinga@kanebiotech.com

www.kanebiotech.com

Ray Dupuis, CPA, MBA

Chief Financial Officer

rdupuis@kanebiotech.com

ir@kanebiotech.com

TSXVENTURE

KNE

OTC MARKETS

~$0.04 CAD

KNBIF

US Symbol

"We're transforming wound care—be part of this journey."

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