Illumina, Inc.NASDAQ: ILMN

ILMN Q3'26 Earnings Supplement

· Issued by Illumina, Inc.

Summary by 6ix AI

Illumina, a maker of sequencing and microarray products, posted total revenue of $1,129 million and net income under standard accounting rules (GAAP) of $220 million, or $1.43 per diluted share, for the third quarter of 2026. That compares with revenue of $1,084 million and net income of $150 million in the third quarter of 2025.

Key details

  • Third-quarter 2026 revenue was reduced by $37 million of customer refunds accrued after Illumina recognized a benefit from refunds of IEEPA tariffs (US tariffs imposed under the International Emergency Economic Powers Act); revenue excluding these refunds was $1,166 million.
  • Non-GAAP (adjusted, excluding items such as acquisition-related costs and investment gains or losses) net income was $249 million, or $1.62 per diluted share, for the third quarter of 2026.
  • GAAP gross margin was 74% and operating profit was $305 million for the third quarter of 2026.
  • Cash provided by operating activities was $419 million and free cash flow (that cash minus equipment purchases) was $378 million in the third quarter of 2026. Cash and cash equivalents were $1,289 million at the end of the quarter.
  • By region, third-quarter 2026 revenue was $637 million in the United States and Canada, $347 million in Europe, Middle East, Africa and Latin America, $59 million in Greater China and $86 million in Asia-Pacific.

6ix AI wrote this summary from the release below and checked it against the release.

‌Condensed Consolidated Balance Sheets

2024

2025

2026

(in millions) ASSETS

Current assets:

Cash and cash equivalents Short-term investments (a) Accounts receivable, net Inventory, net

Prepaid expenses and other current assets Total current assets

Property and equipment, net Operating lease right-of-use assets Goodwill

Intangible assets, net Deferred tax assets, net (b) Other assets

Total assets

LIABILITIES AND STOCKHOLDERS' EQUITY

Current liabilities:

Accounts payable Accrued liabilities

Term debt, current portion Total current liabilities

Operating lease liabilities Term debt

Other long-term liabilities Stockholders' equity

Total liabilities and stockholders' equity

unaudited unaudited unaudited

1Q 24

2Q 24

3Q 24

4Q 24

$ 1,108

$ 920

$ 869

$ 1,127

-

74

70

93

635

641

699

735

584

561

574

547

256

263

161

244

2,583

2,459

2,373

2,746

964

859

832

815

550

460

453

419

2,545

1,079

1,113

1,113

2,940

278

305

295

-

632

617

567

458

314

321

348

$ 10,040

$ 6,081

$ 6,014

$ 6,303

$ 201

$ 199

$ 191

$ 221

1,273

1,265

784

827

-

744

-

499

1,474

2,208

975

1,547

700

616

613

554

1,490

1,490

1,988

1,490

642

331

313

339

5,734

1,436

2,125

2,373

$ 10,040

$ 6,081

$ 6,014

$ 6,303

1Q 25

2Q 25

3Q 25

4Q 25

$ 1,113

$ 934

$ 1,050

$ 1,418

124

221

228

215

699

701

729

854

537

575

590

564

200

210

199

238

2,673

2,641

2,796

3,289

782

764

748

759

410

397

382

370

1,113

1,113

1,113

1,113

278

238

225

210

553

534

490

454

373

400

423

449

$ 6,182

$ 6,087

$ 6,177

$ 6,644

$ 207

$ 200

$ 218

$ 240

734

762

746

846

499

499

998

499

1,440

1,461

1,962

1,585

539

528

506

486

1,491

1,492

994

1,490

344

348

334

360

2,368

2,258

2,381

2,723

$ 6,182

$ 6,087

$ 6,177

$ 6,644

1Q 26 2Q 26 3Q 26

$ 1,089 $ 1,040 $ 1,289

66 128 48

738 764 738

611 629 667

234 273 293

2,738 2,834 3,035

755 745 731

371 362 356

1,284 1,284 1,284

430 410 391

458 439 454

523 576 561

$ 6,559 $ 6,650 $ 6,812

$ 218 $ 230 $ 241

849 848 915

499 500 -

1,566 1,578 1,156

475 454 439

1,490 1,491 1,789

352 289 283

2,676 2,838 3,145

$ 6,559 $ 6,650 $ 6,812

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

(a) Short-term investments was included in Prepaid expenses and other current assets in Q1 2024.

(b) Deferred tax assets, net was included in Other assets in Q1 2024.

‌Condensed Consolidated Statements of Operations

2026

2025

2024

1Q 24

2Q 24

3Q 24

4Q 24

FY 24

$ 876

200

$ 927

185

$ 914

166

$ 939

165

$ 3,656

716

1,076

1,112

1,080

1,104

4,372

255

250

235

278

1,017

106

95

84

82

367

48

46

16

16

127

409

391

335

376

1,511

667

721

745

728

2,861

339

325

253

256

1,169

439

147

239

279

1,092

-

1,886

-

-

1,889

-

-

(488)

18

(456)

778

2,358

4

553

3,694

(111)

(1,637)

741

175

(833)

2

(339)

(21)

13

(346)

(109)

(1,976)

720

188

(1,179)

17

12

15

1

44

$ (126)

$(1,988)

$ 705

$ 187

$(1,223)

$ (0.79)

$(12.48)

$ 4.43

$ 1.17

$ (7.69)

$ (0.79)

$(12.48)

$ 4.42

$ 1.17

$ (7.69)

159

159

159

159

159

159

159

160

160

159

62 %

65 %

69 %

66 %

65 %

31 %

29 %

23 %

23 %

27 %

41 %

13 %

22 %

25 %

25 %

- %

170 %

- %

- %

43 %

- %

- %

(45)%

2 %

(10)%

72 %

212 %

- %

50 %

85 %

(10)%

(147)%

69 %

16 %

(19)%

(15)%

(1)%

2 %

1 %

(4)%

1Q 25

2Q 25

3Q 25

4Q 25

FY 25

$ 880

161

$ 912

147

$ 927

157

$ 990

169

$ 3,709

634

1,041

1,059

1,084

1,159

4,343

253

276

267

312

1,107

88

71

68

72

300

17

17

16

16

66

358

364

351

400

1,473

683

695

733

759

2,870

252

247

229

239

967

267

234

277

310

1,086

-

-

-

-

-

-

-

-

8

10

519

481

506

557

2,063

164

214

227

202

807

18

92

(7)

176

279

182

306

220

378

1,086

51

71

70

44

236

$ 131

$ 235

$ 150

$ 334

$ 850

$ 0.83

$ 1.49

$ 0.98

$ 2.18

$ 5.47

$ 0.82

$ 1.49

$ 0.98

$ 2.16

$ 5.45

159

157

153

153

155

159

157

154

154

156

66 %

66 %

68 %

66 %

66 %

24 %

23 %

21 %

21 %

22 %

26 %

22 %

26 %

27 %

25 %

- %

- %

- %

- %

- %

- %

- %

- %

1 %

- %

50 %

45 %

47 %

48 %

48 %

16 %

20 %

21 %

17 %

19 %

28 %

23 %

32 %

12 %

22 %

1Q 26

2Q 26

3Q 26

FY 26

$ 917

174

$ 982

177

$ 946

183

$ 2,845

535

1,091

1,159

1,129

3,380

273

291

199

763

80

80

82

243

17

18

18

53

370

389

299

1,059

721

770

830

2,321

240

252

244

736

272

273

281

826

-

-

-

-

-

-

-

-

512

525

525

1,562

209

245

305

759

(52)

15

(41)

(78)

157

260

264

681

23

53

44

120

$ 134

$ 207

$ 220

$ 561

$ 0.88

$ 1.37

$ 1.46

$ 3.70

$ 0.87

$ 1.35

$ 1.43

$ 3.65

153

151

151

152

154

153

154

154

66 %

66 %

74 %

69 %

22 %

22 %

22 %

22 %

25 %

24 %

25 %

24 %

- %

- %

- %

- %

- %

- %

- %

- %

47 %

45 %

47 %

46 %

19 %

21 %

27 %

23 %

15 %

21 %

16 %

18 %

unaudited unaudited unaudited

(in millions, except per share amounts and %)

Revenue:

Product revenue

Service and other revenue Total revenue

Cost of revenue:

Cost of product revenue

Cost of service and other revenue Amortization of acquired intangible assets Total cost of revenue

Gross profit

Operating expense:

Research and development Selling, general and administrative

Goodwill and intangible impairment (a) Legal contingency and settlement (a) Total operating expense

Income (loss) from operations Other income (expense), net

Income (loss) before income taxes Provision for income taxes

Net income (loss) Earnings (loss) per share:

Basic Diluted

Shares used in computing earnings (loss) per share: Basic

Diluted

Gross margin

R&D as % of revenue SG&A as % of revenue

Goodwill and intangible impairment as % of revenue Legal contingency and settlement as % of revenue Operating expenses as % of revenue

Operating margin Tax rate

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

(a) Goodwill and intangible impairment and legal contingency and settlement are broken out from R&D and SG&A when material. As a result, amounts may not crossfoot.

‌Consolidated Non-GAAP Data unaudited

See reconciliations between GAAP and non-GAAP tables within this workbook for reconciliations of the non-GAAP financial measures to GAAP

2024

2025

2026

(in millions, except per share amounts and %)

1Q 24

2Q 24

3Q 24

4Q 24

FY 24

1Q 25

2Q 25

3Q 25

4Q 25

FY 25

1Q 26

2Q 26

3Q 26

FY 26

Revenue

$ 1,076

$ 1,112

$ 1,080

$ 1,104

$ 4,372

$ 1,041

$ 1,059

$ 1,084

$ 1,159

$ 4,343

$ 1,091

$ 1,159

$ 1,129

$ 3,380

Gross profit

$ 716

$ 767

$ 761

$ 745

$ 2,990

$ 702

$ 735

$ 750

$ 777

$ 2,964

$ 744

$ 790

$ 850

$ 2,385

Research and development expense

$ 335

$ 325

$ 249

$ 255

$ 1,163

$ 241

$ 243

$ 228

$ 238

$ 950

$ 239

$ 252

$ 243

$ 733

Selling, general and administrative expense

$ 349

$ 358

$ 268

$ 271

$ 1,247

$ 248

$ 241

$ 256

$ 264

$ 1,009

$ 267

$ 278

$ 282

$ 827

Operating profit

$ 33

$ 84

$ 244

$ 218

$ 580

$ 212

$ 252

$ 265

$ 275

$ 1,004

$ 239

$ 260

$ 325

$ 824

Net income

$ 14

$ 57

$ 181

$ 138

$ 390

$ 154

$ 187

$ 206

$ 208

$ 756

$ 177

$ 201

$ 249

$ 627

Diluted EPS

$ 0.09

$ 0.36

$ 1.14

$ 0.86

$ 2.45

$ 0.97

$ 1.19

$ 1.34

$ 1.35

$ 4.84

$ 1.15

$ 1.31

$ 1.62

$ 4.08

Tax rate

46.4 %

22.3 %

21.0 %

31.1 %

26.3 %

22.0 %

22.2 %

18.6 %

19.5 %

20.5 %

20.5 %

20.5 %

20.5 %

20.5 %

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

‌Core Illumina Non-GAAP Data unaudited

See reconciliations between GAAP and non-GAAP tables within this workbook for reconciliations of the non-GAAP financial measures to GAAP

2024

2025

2026

(in millions, except per share amounts and %)

1Q 24

2Q 24

3Q 24

4Q 24

FY 24

1Q 25

2Q 25

3Q 25

4Q 25

FY 25

1Q 26

2Q 26

3Q 26

FY 26

Revenue (a)

$ 1,056

$ 1,092

$ 1,080

$ 1,104

$ 4,332

$ 1,041

$ 1,059

$ 1,084

$ 1,159

$ 4,343

$ 1,091

$ 1,159

$ 1,129

$ 3,380

Gross profit

$ 708

$ 758

$ 761

$ 745

$ 2,973

$ 702

$ 735

$ 750

$ 777

$ 2,964

$ 744

$ 790

$ 850

$ 2,385

Research and development expense

$ 237

$ 241

$ 249

$ 255

$ 982

$ 241

$ 243

$ 228

$ 238

$ 950

$ 239

$ 252

$ 243

$ 733

Selling, general and administrative expense

$ 254

$ 275

$ 268

$ 271

$ 1,069

$ 248

$ 241

$ 256

$ 264

$ 1,009

$ 267

$ 278

$ 282

$ 827

Operating profit

$ 218

$ 242

$ 244

$ 218

$ 922

$ 212

$ 252

$ 265

$ 275

$ 1,004

$ 239

$ 260

$ 325

$ 824

Net income

$ 155

$ 174

$ 181

$ 152

$ 663

$ 154

$ 187

$ 206

$ 208

$ 756

$ 177

$ 201

$ 249

$ 627

Diluted EPS

$ 0.98

$ 1.09

$ 1.14

$ 0.95

$ 4.16

$ 0.97

$ 1.19

$ 1.34

$ 1.35

$ 4.84

$ 1.15

$ 1.31

$ 1.62

$ 4.08

Tax rate

25.7 %

24.2 %

21.0 %

23.7 %

23.6 %

22.0 %

22.2 %

18.6 %

19.5 %

20.5 %

20.5 %

20.5 %

20.5 %

20.5 %

(a) Amounts include intercompany revenue between segments, which is eliminated in consolidation.

‌Consolidated Reconciliation Between GAAP and Non-GAAP Net Income (Loss) and Diluted Earnings (Loss) Per Share unaudited

2024

2025

2026

1Q 24 2Q 24 3Q 24 4Q 24

FY 24

$ (0.79) $ (12.48) $ 4.42 $ 1.17

$ (7.69)

0.31 0.29 0.09 0.10

0.81

0.03 - 0.03 0.01

0.04

0.57 (1.33) (0.18) 0.04

(0.97)

- - (3.06) 0.11

(2.87)

- 11.84 - -

11.88

(0.05) 2.06 0.04 (0.19)

1.85

0.02 (0.02) (0.20) (0.38)

(0.60)

$ 0.09 $ 0.36 $ 1.14 $ 0.86

$ 2.45

$ (126) $ (1,988) $ 705 $ 187

$ (1,223)

49 46 16 17

129

4 - 4 1

6

91 (211) (30) 7

(155)

- - (488) 18

(456)

- 1,886 - -

1,889

(8) 328 7 (31)

295

4 (4) (33) (61)

(95)

$ 14 $ 57 $ 181 $ 138

$ 390

1Q 25 2Q 25 3Q 25 4Q 25

FY 25

$ 0.82 $ 1.49 $ 0.98 $ 2.16

$ 5.45

0.12 0.25 0.11 0.12

0.60

0.07 0.03 0.01 0.01

0.11

0.12 (0.04) 0.13 0.30

0.48

- - - 0.05

0.06

- - - -

-

(0.21) (0.65) (0.04) (1.25)

(2.13)

0.05 0.11 0.15 (0.04)

0.27

$ 0.97 $ 1.19 $ 1.34 $ 1.35

$ 4.84

$ 131 $ 235 $ 150 $ 334

$ 850

19 40 17 18

94

11 4 1 1

17

19 (7) 21 45

76

- - - 8

10

- - - -

-

(33) (102) (6) (192)

(333)

7 17 23 (6)

42

$ 154 $ 187 $ 206 $ 208

$ 756

1Q 26 2Q 26 3Q 26

FY 26

$ 0.87 $ 1.35 $ 1.43

$ 3.65

0.15 0.13 0.13

0.42

0.01 - 0.01

0.02

0.03 (0.03) (0.01)

(0.01)

- - -

-

- - -

-

0.24 (0.15) 0.19

0.27

(0.15) 0.01 (0.13)

(0.27)

$ 1.15 $ 1.31 $ 1.62

$ 4.08

$ 134 $ 207 $ 220

$ 561

23 20 20

64

1 - 1

3

5 (4) (1)

(2)

- - -

-

- - -

-

37 (23) 29

42

(23) 1 (20)

(41)

$ 177 $ 201 $ 249

$ 627

(in millions, except per share amounts)

Table 1: Reconciliation of GAAP and Non-GAAP diluted earnings (loss) per share

GAAP earnings (loss) per share - diluted Cost of revenue (b)

Research and development costs (b) Selling, general and administrative costs (b) Legal contingency and settlement (b) Goodwill and intangible impairment (b) Other expense (income), net (b)

Provision for income taxes (b)

Non-GAAP earnings per share - diluted (a)

Table 2: Reconciliation of GAAP and Non-GAAP net income (loss)

GAAP net income (loss) Cost of revenue (b)

Research and development costs (b) Selling, general and administrative costs (b) Legal contingency and settlement (b) Goodwill and intangible impairment (b) Other expense (income), net (b)

Provision for income taxes (b) Non-GAAP net income (a)

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

(a) Non-GAAP net income and diluted earnings per share exclude the effects of the pro forma adjustments detailed above. Non-GAAP net income and diluted earnings per share are key components of the financial metrics utilized by the company's board of directors to measure, in part, management's performance and determine significant elements of management's compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing our past and future operating performance.

(b) Refer to Reconciliations between GAAP and Non-GAAP Results of Operations for details of amounts.

‌Core Illumina Reconciliation Between GAAP and Non-GAAP Net Income and Diluted Earnings Per Share unaudited

2026

2025

2024

1Q24 2Q24 3Q24 4Q24

FY 24

$ 0.44 $ 0.41 $ 4.03 $ 0.73

$ 5.61

0.09 0.10 0.10 0.10

0.40

0.03 - 0.03 0.01

0.04

0.52 (1.35) (0.18) 0.04

(1.06)

- - - -

0.02

- - (3.07) 0.11

(2.87)

(0.05) 2.06 0.04 (0.19)

1.86

(0.05) (0.13) 0.19 0.15

0.16

$ 0.98 $ 1.09 $ 1.14 $ 0.95

$ 4.16

$ 70 $ 66 $ 642 $ 117

$ 894

15 15 16 17

64

4 - 4 1

6

83 (215) (29) 25

(168)

- - - -

3

- - (488) -

(456)

(8) 328 7 (31)

295

(9) (20) 29 23

25

$ 155 $ 174 $ 181 $ 152

$ 663

1Q 25 2Q 25 3Q25 4Q25

FY25

$ 0.82 $ 1.49 $ 0.98 $ 2.16

$ 5.45

0.12 0.25 0.11 0.12

0.60

0.07 0.03 0.01 0.01

0.11

0.12 (0.04) 0.13 0.30

0.48

- - - -

-

- - - 0.05

0.06

(0.21) (0.65) (0.04) (1.25)

(2.13)

0.05 0.11 0.15 (0.04)

0.27

$ 0.97 $ 1.19 $ 1.34 $ 1.35

$ 4.84

$ 131 $ 235 $ 150 $ 334

$ 850

19 40 17 18

94

11 4 1 1

17

19 (7) 21 45

76

- - - -

-

- - - 8

10

(33) (102) (6) (192)

(333)

7 17 23 (6)

42

$ 154 $ 187 $ 206 $ 208

$ 756

1Q26 2Q26 3Q26

FY26

$ 0.87 $ 1.35 $ 1.43

$ 3.65

0.15 0.13 0.13

0.42

0.01 - 0.01

0.02

0.03 (0.03) (0.01)

(0.01)

- - -

-

- - -

-

0.24 (0.15) 0.19

0.27

(0.15) 0.01 (0.13)

(0.27)

$ 1.15 $ 1.31 $ 1.62

$ 4.08

$ 134 $ 207 $ 220

$ 561

23 20 20

64

1 - 1

3

5 (4) (1)

(2)

- - -

-

- - -

-

37 (23) 29

42

(23) 1 (20)

(41)

$ 177 $ 201 $ 249

$ 627

(in millions, except per share amounts)

Table 3: Reconciliation of GAAP and Non-GAAP diluted earnings per share

GAAP earnings per share - diluted Cost of revenue (b)

Research and development costs (b) Selling, general and administrative costs (b) Goodwill and intangible impairment (b) Legal contingency and settlement (b)

Other expense (income), net (b) Provision for income taxes (b)

Non-GAAP earnings per share - diluted (a)

Table 4: Reconciliation of GAAP and Non-GAAP net income

GAAP net income Cost of revenue (b)

Research and development costs (b) Selling, general and administrative costs (b) Goodwill and intangible impairment (b) Legal contingency and settlement (b)

Other expense (income), net (b) Provision for income taxes (b)

Non-GAAP net income (a)

  1. Non-GAAP net income and diluted earnings per share exclude the effects of the pro forma adjustments detailed above. Non-GAAP net income and diluted earnings per share are key components of the financial metrics utilized by the company's board of directors to measure, in part, management's performance and determine significant elements of management's compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing our past and future operating performance.

  2. Refer to Reconciliations between GAAP and Non-GAAP Results of Operations for details of amounts.

‌Table 5: Reconciliation Between GAAP and Non-GAAP Results of Operations unaudited

2026

1Q 26 2Q 26 3Q 26

FY26

Core/Consolidated Core/Consolidated Core/Consolidated

$ 721 $ 770 $ 830

23 20 20

Core/Consolidated

$ 2,321

64

$ 744 $ 790 $ 850

$ 2,385

$ 240 $ 252 $ 244

(1) - (1)

$ 736

(3)

$ 239 $ 252 $ 243

$ 733

$ 272 $ 273 $ 281

1 9 6

(6) (4) (5)

$ 826

16

(15)

$ 267 $ 278 $ 282

$ 827

$ 209 $ 245 $ 305

23 20 20

1 - 1

6 (5) (1)

$ 759

64

3

(2)

$ 239 $ 260 $ 325

$ 824

$ (52) $ 15 $ (41)

37 (23) 29

$ (78)

42

$ (15) $ (8) $ (12)

$ (36)

(in millions)

GAAP gross profit (b) Acquisition-related costs (c)

Non-GAAP gross profit (a)

GAAP research and development expense Acquisition-related costs (c)

Non-GAAP research and development expense

GAAP selling, general and administrative expense Acquisition-related costs (c)

Transformational initiatives (d)

Non-GAAP selling, general and administrative expense

GAAP operating profit Cost of revenue

Research and development costs Selling, general, and administrative costs

Non-GAAP operating profit (a)

GAAP other income (expense), net Strategic investment gain (loss), net (e)

Non-GAAP other income (expense), net (a)

  1. Non-GAAP gross profit, included within non-GAAP operating profit, is a key measure of the effectiveness and efficiency of manufacturing processes, product mix and the average selling prices of our products and services. Non-GAAP operating profit and non-GAAP other income (expense), net exclude the effects of the pro forma adjustments as detailed above. Non-GAAP operating margin is a key component of the financial metrics utilized by the company's board of directors to measure, in part, management's performance and determine significant elements of management's compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing past and future operating performance.

  2. Reconciling amounts are recorded in cost of revenue.

  3. Amounts for 1Q 2026 consist primarily of $17 million for amortization of intangible assets (cost of revenue), $15 million related primarily to legal and other expenses for the SomaLogic acquisition (operating expense), and $6 million related to the amortization of an inventory fair value step-up recognized in SomaLogic purchase accounting (cost of revenue), offset by $16 million for fair value adjustments on our contingent consideration liabilities (operating expense). Amounts for 2Q 2026 consist primarily of $18 million for amortization of intangible assets (cost of revenue), $7 million related to expenses for the SomaLogic and GRAIL acquisitions (operating expense), and $2 million primarily related to the amortization of an inventory fair value step-up recognized in SomaLogic purchase accounting (cost of revenue), offset by $16 million for fair value adjustments on our contingent consideration liabilities (operating expense). Amounts for 3Q 2026 consist primarily of $18 million for amortization of intangible assets (cost of revenue), $5 million related to expenses for the SomaLogic and GRAIL acquisitions (operating expense), and $2 million primarily related to the amortization of an inventory fair value step-up recognized in SomaLogic purchase accounting (cost of revenue), offset by $11 million for fair value adjustments on our contingent consideration liabilities (operating expense).

  4. Amounts for 1Q 2026, 2Q 2026 and 3Q 2026 consist primarily of costs related to implementation efforts to upgrade our ERP system.

  5. Amounts consist of realized and unrealized gains (losses) and impairments on our investments.

FY25

Core/Consolidated

$ 2,870

66

5

23

$ 2,964

$ 967

(1)

(16)

$ 950

$ 1,086

(16)

(39)

(22)

$ 1,009

$ 10

$ (10)

$ -

$ 807

94

17

76

$ 10

$ 1,004

$ 279

(333)

$ (54)

‌Table 5: Reconciliation Between GAAP and Non-GAAP Results of Operations unaudited

2025

(in millions)

1Q 25

2Q 25

3Q 25

4Q 25

Core/Consolidated

Core/Consolidated

Core/Consolidated

Core/Consolidated

GAAP gross profit (b)

$

683

$

695

$

733

$

759

Acquisition-related costs (c)

17

16

16

16

Transformational initiatives (d)

2

1

1

2

Intangible impairment

-

23

-

-

Non-GAAP gross profit (a)

$

702

$

735

$

750

$

777

GAAP research and development expense

$

252

$

247

$

229

$

239

Acquisition-related costs (c)

-

-

-

-

Transformational initiatives (d)

(11)

(4)

(1)

(1)

Non-GAAP research and development expense

$

241

$

243

$

228

$

238

GAAP selling, general and administrative expense

$

267

$

234

$

277

$

310

Acquisition-related costs (c)

4

12

(11)

(21)

Transformational initiatives (d)

(18)

(5)

(10)

(6)

Other (f)

(5)

-

-

(19)

Non-GAAP selling, general and administrative expense

$

248

$

241

$

256

$

264

GAAP legal contingency and settlement

$

-

$

-

$

-

$

8

Legal contingency and settlement

-

-

-

(8)

Non-GAAP legal contingency and settlement

$

-

$

-

$

-

$

-

GAAP operating profit

$

164

$

214

$

227

$

202

Cost of revenue

19

40

17

18

Research and development costs

11

4

1

1

Selling, general, and administrative costs

18

(6)

20

46

Legal contingency and settlement

-

0

-

8

Non-GAAP operating profit (a)

$

212

$

252

$

265

$

275

GAAP other income (expense), net

$

18

$

92

$

(7)

$

176

Strategic investment gain, net (e)

(33)

(102)

(6)

(192)

Non-GAAP other expense, net (a)

$

(15)

$

(10)

$

(13)

$

(16)

  1. Non-GAAP gross profit, included within non-GAAP operating profit (loss), is a key measure of the effectiveness and efficiency of manufacturing processes, product mix and the average selling prices of our products and services. Non-GAAP operating profit (loss) and non-GAAP other income (expense), net exclude the effects of the pro forma adjustments as detailed above. Non-GAAP operating margin is a key component of the financial metrics utilized by the company's board of directors to measure, in part, management's performance and determine significant elements of management's compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing past and future operating performance.

  2. Reconciling amounts are recorded in cost of revenue.

  3. Amounts for 1Q 2025 consist of $17 million for amortization of intangible assets (cost of revenue) and $7 million related primarily to legal expenses for the GRAIL acquisition (SG&A), offset by $11 million for fair value adjustments on our contingent consideration liabilities (SG&A). Amounts for 2Q 2025 consist of $16 million for amortization of intangible assets (cost of revenue) and $9 million related primarily to legal and other expenses for the pending SomaLogic acquisition and legal expenses for the GRAIL acquisition (SG&A), offset by $21 million for fair value adjustments on our contingent consideration liabilities (SG&A). Amounts for 3Q 2025 consist of $16 million for amortization of intangible assets (cost of revenue), $4 million related to a lease impairment (SG&A), $4 million for legal expenses primarily related to the pending SomaLogic acquisition (SG&A), and $3 million for fair value adjustments on our contingent consideration liabilities (SG&A). Amounts for 4Q 2025 consist of $16 million for amortization of intangible assets (cost of revenue), $11 million for fair value adjustments on our contingent consideration liabilities (SG&A) and $10 million related primarily to legal and other expenses for the pending SomaLogic acquisition and legal expenses for the GRAIL acquisition (SG&A).

  4. Amounts for 1Q 2025 and 2Q 2025 consist primarily of employee severance costs related to restructuring activities. Amounts for 3Q 2025 consist primarily of costs related to implementation efforts to upgrade our ERP system (SG&A). Amounts for 4Q 2025 consist primarily of employee severance costs related to restructuring activities and costs related to implementation efforts to upgrade our ERP system (SG&A). Amounts for YTD 2025 consist primarily of employee severance costs related to restructuring activities of $47 million and costs related to implementation efforts to upgrade our ERP system of $14 million.

  5. Amounts consist of realized and unrealized gains (losses) and impairments on our investments.

  6. Amounts for 1Q 2025 consist of $3 million for board membership changes and $2 million for legal contingency accruals. Amounts for 4Q 2025 consist of a $19 million donation to the Illumina foundation.

Table 5: Reconciliation Between GAAP and Non-GAAP Results of Operations

unaudited

1Q 24 2Q 24 3Q 24 4Q 24

FY 24

Core Illumina GRAIL Eliminations Consolidated Core Illumina GRAIL Eliminations Consolidated Core Illumina GRAIL Eliminations Consolidated Core Illumina GRAIL Eliminations Consolidated Core Illumina GRAIL Eliminations Consolidated

$ 693 $ (21) $ (4) $ 667 $ 743 $ (16) $ (6) $ 721 $ 745 $ - $ - $ 745 $ 728 $ - $ - $ 728 $ 2,909 $ (38) $ (10) $ 2,861

15 34 - 49 15 31 - 46 16 - - 16 17 - - 17 63 65 - 128

- - - - - - - - - - - - - - - - 1 - - 1

$ 708 $ 12 $ (4) $ 716 $ 758 $ 15 $ (6) $ 767 $ 761 $ - $ - $ 761 $ 745 $ - $ - $ 745 $ 2,973 $ 27 $ (10) $ 2,990

$

$

241 $

- (1)

(3)

237 $

101 $

-

-

-

101 $

(3) $

-

-

-

(3) $

339 $

- (1)

(3)

335 $

241 $

-

-

-

241 $

88 $

-

-

-

88 $

(4) $

-

-

-

(4) $

325 $

-

-

-

325 $

253 $

(3)

(1)

-

249 $

  • $

    -

    -

    -

  • $

  • $

    -

    -

    -

  • $

253 $

(3)

(1)

-

249 $

256 $

(1)

-

-

255 $

  • $

    -

    -

    -

  • $

  • $

    -

    -

    -

  • $

256 $

(1)

-

-

255 $

988 $

(4)

(2)

-

982 $

189 $

-

-

-

189 $

(8) $

-

-

-

(8) $

1,169

(4)

(2)

- 1,163

$

336 $

- (16)

(25)

(34)

104 $

(1)

- (6)

(1)

(1) $

-

-

-

-

439 $

(1)

(16)

(31)

(35)

60 $

- 271

(46)

(3)

88 $

(1)

- (3)

-

(1) $

-

-

-

-

147 $

(1)

271

(49)

(3)

239 $

- 49

(15)

(5)

- $

-

-

-

-

- $

-

-

-

-

239 $

- 49

(15)

(5)

279 $

-

- 7

(15)

- $

-

-

-

-

- $

-

-

-

-

279 $

-

- 7

(15)

(7) - - (7) (7) - - (7) - - - - - - - -

$ 254 $ 96 $ (1) $ 349 $ 275 $ 84 $ (1) $ 358 $ 268 $ - $ - $ 268 $ 271 $ - $ - $ 271 $

900 $

(1)

315

(87)

(58)

-

1,069 $

192 $

(2)

- (11)

(1)

-

178 $

  • $

    -

    -

    -

    -

    -

  • $

1,092

(3)

315

(98)

(59)

- 1,247

$

- $

-

- $

-

- $

-

- $

-

- $

-

1,886 $

(1,466)

- $

-

1,886 $

(1,466)

- $

-

- $

-

- $

-

- $

-

- $

-

- $

-

- $

-

- $

-

- - - - - (420) - (420) - - - - - - - -

$ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $ - $

3 $

- (3)

- $

1,886 $

(1,466)

(420)

- $

  • $

    -

    -

  • $

1,889

(1,466)

(423)

-

$

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

  • $

    -

  • $

(488) $

488

- $

- $

- $

(488) $

- - 488

18 $

(18)

- $

- $

- $

18 $

- - (18)

$

- $

- $

- $

- $

- $

- $

(456) $

456

- $

  • $

    -

  • $

  • $

    -

  • $

(456)

456

-

$

$

116 $

15

4

83

-

-

218 $

(226) $

34

- 8

-

-

(185) $

  • $

    -

    -

    -

    -

    -

  • $

(111) $

49

4

91

-

-

33 $

442 $

15

- (215)

-

-

242 $

(2,078) $

31

- 4

1,886

-

(157) $

(1) $

-

-

-

-

-

(1) $

(1,637) $

46

- (211)

1,886

-

84 $

741 $

16

4

(29)

- (488)

244 $

  • $

    -

    -

    -

    -

    -

  • $

  • $

    -

    -

    -

    -

    -

  • $

741 $

16

4

(29)

- (488)

244 $

175 $

17

1

25

-

-

218 $

  • $

    -

    -

    -

    -

    -

  • $

  • $

    -

    -

    -

    -

    -

  • $

175 $

17

1

25

-

-

218 $

1,473 $

64

6

(168)

3

(456)

922 $

(2,305) $

65

- 13

1,886

- (341) $

(1) $

-

-

-

-

-

(1) $

(833)

129

6

(155)

1,889

(456)

580

$

$

(1) $

(6)

(3)

1

(9) $

3 $

-

-

-

3 $

  • $

    -

    -

    -

  • $

2 $

(6)

(3)

1

(6) $

(341) $

334

(8)

2

(13) $

2 $

-

-

-

2 $

  • $

    -

    -

    -

  • $

(339) $

334

(8)

2

(11) $

(21) $

12

(4)

(1)

(14) $

  • $

    -

    -

    -

  • $

  • $

    -

    -

    -

  • $

(21) $

12

(4)

(1)

(14) $

13 $

(31)

-

-

(18) $

  • $

    -

    -

    -

  • $

  • $

    -

    -

    -

  • $

13 $

(31)

-

-

(18) $

(350) $

308

(15)

2

(55) $

5 $

-

-

-

5 $

(1) $

-

-

-

(1) $

(346)

308

(15)

2

(51)

2024

‌(in millions)

GAAP gross profit (loss) (b)

Amortization of acquired intangible assets Restructuring (g)

Non-GAAP gross profit (a)

GAAP research and development expense Acquisition-related expenses (d) Restructuring (g)

IPR&D impairment (i)

Non-GAAP research and development expense

GAAP selling, general and administrative expense Amortization of acquired intangible assets Contingent consideration liabilities (c) Acquisition-related expenses (d)

Restructuring (g)

Accrued interest on EC fine (h)

Non-GAAP selling, general and administrative expense

GAAP goodwill and intangible impairment Goodwill impairment (i)

Intangible (IPR&D) impairment (i)

Non-GAAP goodwill and intangible impairment

GAAP legal contingency and settlement Legal contingency and settlement (h)

Non-GAAP legal contingency and settlement

GAAP operating profit (loss) Cost of revenue

Research and development costs Selling, general, and administrative costs Goodwill and intangible impairment Legal contingency and settlement

Non-GAAP operating profit (loss) (a)

GAAP other (expense) income, net

Strategic investment related gain (loss), net (e) Gain on Helix contingent value right (f) Acquisition-related expenses (d)

Non-GAAP other (expense) income, net (a)

  1. Non-GAAP gross profit, included within non-GAAP operating profit (loss), is a key measure of the effectiveness and efficiency of manufacturing processes, product mix and the average selling prices of our products and services. Non-GAAP operating profit (loss) and non-GAAP other (expense) income, net exclude the effects of the pro forma adjustments as detailed above. Non-GAAP operating margin is a key component of the financial metrics utilized by the company's board of directors to measure, in part, management's performance and determine significant elements of management's compensation. Management has excluded the effects of these items in these measures to assist investors in analyzing and assessing past and future operating performance.

  2. Reconciling amounts are recorded in cost of revenue.

  3. Amounts consist primarily of fair value adjustments for our contingent consideration liability related to GRAIL.

  4. Amounts consist primarily of legal and other expenses related to the acquisition and divestiture of GRAIL.

  5. Amounts consist primarily of mark-to-market adjustments and impairments from our strategic investments.

  6. Amounts consist of fair value adjustments related to our Helix contingent value right.

  7. Amounts consist primarily of lease and other asset impairments, as well as employee severance costs, related to restructuring activities.

  8. Amounts consist of accrued interest on the fine imposed by the European Commission and reversal of the accrued fine, including interest.

  9. Amounts consist of goodwill and IPR&D intangible asset impairments related to GRAIL and an IPR&D intangible asset impairment related to Core Illumina.

‌Consolidated Reconciliation Between GAAP and Non-GAAP Tax Provision unaudited

2024

2025

2026

1Q24

2Q24

3Q24

4Q24

FY 24

1Q25

2Q25

3Q25

4Q25

FY 25

1Q26

2Q26

3Q26

FY 26

(15.3)%

(0.6)%

2.1 %

0.6 %

(3.8)%

27.9 %

23.4 %

31.8 %

11.6 %

21.7 %

14.8 %

20.5 %

16.4 %

17.6 %

$ 17

$ 12

$ 15

$ 1

$ 44

$ 51

$ 71

$ 70

$ 44

$ 236

$ 23

$ 53

$ 44

$ 120

13

104

59

23

201

(1)

(16)

(22)

17

(23)

24

(3)

19

40

-

(1)

(1)

(13)

(16)

(6)

(1)

(1)

(11)

(19)

(1)

2

1

1

(17)

(99)

(25)

51

(90)

-

-

-

-

-

-

-

-

-

$ 13

$ 16

$ 48

$ 62

$ 139

$ 44

$ 54

$ 47

$ 50

$ 194

$ 46

$ 52

$ 64

$ 161

46.4 %

22.3 %

21.0 %

31.1 %

26.3 %

22.0 %

22.2 %

18.6 %

19.5 %

20.5 %

20.5 %

20.5 %

20.5 %

20.5 %

(in millions, except percentages)

GAAP tax rate GAAP tax provision

Non-GAAP tax expense (b) Income tax provision (c)

GILTI, U.S. foreign tax credits, and global minimum top-up tax (d) Non-GAAP tax provision (a)

Non-GAAP tax rate (a)

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

  1. Non-GAAP tax provision excludes the effects of the pro forma adjustments as detailed above, which have been excluded to assist investors in analyzing and assessing past and future operating performance.

  2. Non-GAAP tax expense reflects the tax impact related to the non-GAAP adjustments listed in our "Reconciliation of GAAP and Non-GAAP Net Income (Loss) and Diluted Earnings (Loss) Per Share." For 3Q 2025 and YTD 2025, non-GAAP tax expense also includes a one-time $42 million valuation allowance adjustment recorded in 3Q 2025 against deferred tax assets associated with certain U.S. foreign tax credits as a result of the

    U.S. tax legislation that was signed on July 4, 2025.

  3. Amounts represent the difference between book and tax accounting related to stock-based compensation cost.

  4. Amounts represent the impact of GRAIL pre-acquisition net operating losses on GILTI, the utilization of U.S. foreign tax credits, and the Pillar Two global minimum top-up tax, which no longer applies starting in 2025 since the GRAIL pre-acquisition net operating losses were fully utilized in prior years.

Condensed Consolidated Statements of Cash Flows

2024

2025

2026

1Q24

2Q24

3Q24

4Q24

FY 24

1Q25

2Q25

3Q25

4Q25

FY 25

1Q26

2Q26

3Q26

FY 26

$ 77

$ 80

$ 316

$ 364

$ 837

$ 240

$ 234

$ 284

$ 321

$ 1,079

$ 289

$ 201

$ 419

$ 909

(48)

(41)

(42)

(48)

(178)

(63)

(49)

(51)

108

(55)

(366)

(121)

50

(438)

35

(225)

(332)

(47)

(570)

(195)

(371)

(115)

(63)

(744)

(251)

(129)

(223)

(602)

(4)

(2)

7

(11)

(10)

4

7

(2)

2

11

(1)

-

3

2

60

(188)

(51)

258

79

(14)

(179)

116

368

291

(329)

(49)

249

(129)

1,048

1,108

920

869

1,048

1,127

1,113

934

1,050

1,127

1,418

1,089

1,040

1,418

$ 1,108

$ 920

$ 869

$ 1,127

$ 1,127

$ 1,113

$ 934

$ 1,050

$ 1,418

$ 1,418

$ 1,089

$ 1,040

$ 1,289

$ 1,289

$ 77

$ 80

$ 316

$ 364

$ 837

$ 240

$ 234

$ 284

$ 321

$ 1,079

$ 289

$ 201

$ 419

$ 909

(36)

(32)

(32)

(42)

(142)

(32)

(30)

(31)

(54)

(148)

(38)

(39)

(41)

(118)

$ 41

$ 48

$ 284

$ 322

$ 695

$ 208

$ 204

$ 253

$ 267

$ 931

$ 251

$ 162

$ 378

$ 791

unaudited unaudited unaudited

(in millions)

Net cash provided by operating activities

Net cash provided by (used in) investing activities Net cash provided by (used in) financing activities

Effect of exchange rate changes on cash and cash equivalents Net increase (decrease) in cash and cash equivalents

Cash and cash equivalents, beginning of period Cash and cash equivalents, end of period

Calculation of free cash flow:

Net cash provided by (used in) operating activities Purchases of property and equipment

Free cash flow (a)

The consolidated results include the results for GRAIL prior to the spin off on June 24, 2024.

  1. Free cash flow, which is a non-GAAP financial measure, is calculated as net cash provided by operating activities reduced by purchases of property and equipment. Free cash flow is useful to management as it is one of the metrics used to evaluate our performance and to compare us with other companies in our industry. However, our calculation of free cash flow may not be comparable to similar measures used by other companies.

‌Core Illumina Reconciliation Between GAAP and Non-GAAP Tax Provision unaudited

2024

2025

2026

1Q24 2Q24 3Q24 4Q24

FY 24

39.3 % 35.0 % 10.8 % 37.9 %

20.4 %

$ 45 $ 35 $ 77 $ 70

$ 229

22 41 26 (15)

73

- (1) (1) (13)

(16)

(13) (20) (54) 5

(82)

$ 54 $ 55 $ 48 $ 47

$ 204

25.7 % 24.2 % 21.0 % 23.7 %

23.6 %

1Q25 2Q25 3Q25 4Q25

FY 25

27.9 % 23.4 % 31.8 % 11.6 %

21.7 %

$ 51 $ 71 $ 70 $ 44

$ 236

(1) (16) (22) 17

(23)

(6) (1) (1) (11)

(19)

- - - -

-

$ 44 $ 54 $ 47 $ 50

$ 194

22.0 % 22.2 % 18.6 % 19.5 %

20.5 %

1Q26 2Q26 3Q26

FY 26

14.8 % 20.5 % 16.4 %

17.6 %

$ 23 $ 53 $ 44

$ 120

24 (3) 19

40

(1) 2 1

1

- - -

-

$ 46 $ 52 $ 64

$ 161

20.5 % 20.5 % 20.5 %

20.5 %

(in millions, except percentages)

GAAP tax rate GAAP tax provision

Non-GAAP tax expense (b) Income tax provision (c)

GILTI, U.S. foreign tax credits, and global minimum top-up tax (d) Non-GAAP tax provision (a)

Non-GAAP tax rate (a)

  1. Non-GAAP tax provision excludes the effects of the pro forma adjustments as detailed above. Management has excluded the effects of these items in this measure to assist investors in analyzing and assessing past and future operating performance.

  2. Non-GAAP tax expense reflects the tax impact related to the non-GAAP adjustments listed in our "Reconciliation of GAAP and Non-GAAP Net Income and Diluted Earnings Per Share." For 3Q 2025 and YTD 2025, non-GAAP tax expense also includes a one-time $42 million valuation allowance adjustment recorded in 3Q 2025 against deferred tax assets associated with certain U.S. foreign tax credits as a result of the U.S. tax legislation that was signed on July 4, 2025.

  3. Amounts represent the difference between book and tax accounting related to stock-based compensation cost.

  4. Amounts represent the impact of GRAIL pre-acquisition net operating losses on GILTI, the utilization of U.S. foreign tax credits, and the Pillar Two global minimum top-up tax, which no longer applies starting in 2025 since the GRAIL pre-acquisition net operating losses were fully utilized in prior years.

2026

2025

2024

Core Illumina Free Cash Flows unaudited

1Q24

2Q24

3Q24

4Q24

FY 24

$ 284

$ 243

$ 316

$ 364

$ 1,207

(33)

(30)

(32)

(42)

(137)

$ 251

$ 213

$ 284

$ 322

$ 1,070

1Q25

2Q25

3Q25

4Q25

FY25

$ 240

$ 234

$ 284

$ 321

$ 1,079

(32)

(30)

(31)

(54)

(148)

$ 208

$ 204

$ 253

$ 267

$ 931

1Q26

2Q26

3Q26

FY26

$ 289

$ 201

$ 419

$ 909

(38)

(39)

(41)

(118)

$ 251

$ 162

$ 378

$ 791

(in millions)

Calculation of free cash flow:

Net cash provided by operating activities Purchases of property and equipment Free cash flow (a)

  1. Free cash flow, which is a non-GAAP financial measure, is calculated as net cash provided by operating activities reduced by purchases of property and equipment. Free cash flow is useful to management as it is one of the metrics used to evaluate our performance and to compare us with other companies in our industry. However, our calculation of free cash flow may not be comparable to similar measures used by other companies.

‌Core Illumina - Revenue by Geographic Region

Revenue Excluding Tariff Refunds

2026

2025

2024

1Q24

2Q24

3Q24

4Q24

FY 24

$ 567

$ 604

$ 594

$ 572

$ 2,337

317

336

332

373

1,358

78

75

75

80

308

94

77

79

79

329

$ 1,056

$ 1,092

$ 1,080

$ 1,104

$ 4,332

1Q25

2Q25

3Q25

4Q25

FY 25

$ 555

$ 569

$ 596

$ 621

$ 2,341

332

355

354

394

1,435

72

63

52

55

242

82

72

82

89

325

$ 1,041

$ 1,059

$ 1,084

$ 1,159

$ 4,343

1Q26

2Q26

3Q26

FY 26

$ 590

$ 653

$ 637

$ 1,880

356

368

347

1,072

52

56

59

167

93

82

86

261

$ 1,091

$ 1,159

$ 1,129

$ 3,380

unaudited unaudited unaudited unaudited

3Q 26

3Q 26 Revenue

(in millions)

Tariff Refunds (c)

Excluding Tariff Refunds (c)

REVENUE BY GEOGRAPHIC REGION

USCAN EMEALA

GREATER CHINA (a) APAC

Total Revenue (b)

We implemented a new global commercial structure in Q1 2026 to improve operating efficiencies and better align with local markets. Beginning in Q1 2026, we began reporting regional results for: United States and Canada (USCAN), Europe, Middle East, Africa and Latin America (EMEALA), Greater China, and Asia-Pacific (APAC). Prior period amounts were reclassified to conform to this new presentation.

  1. Region includes revenue from China, Taiwan, and Hong Kong.

  2. Amounts include intercompany revenue between segments, which is eliminated in consolidation.

  3. Revenue was negatively impacted in 3Q 26 due to customer refunds accrued as a result of the benefit from IEEPA tariff refunds we recognized in the quarter. Amounts show revenue impact by region.

$ (28) $ 665

(9) 356

- 59

- 86

$ (37) $ 1,166

Core Illumina Supplementary Data

unaudited

unaudited

unaudited

unaudited

3Q 26 3Q 26 Revenue

Tariff Refunds (b) Excluding Tariff Refunds (b)

$

(28) $

(2) $

(30) $

792

79

871

$

(4) $

- (4)

106

3

109

$

(34) $

980

$

$

(3) $

-

(3) $

158

28

186

$

(37) $

1,166

Revenue Excluding Tariff Refunds

2026

2025

2024

Revenue Excluding Tariff Refunds

2026

2025

2024

1Q 24 2Q 24 3Q 24 4Q 24

FY 24

$ 698 $ 737 $ 741 $ 698

71 78 66 81

$ 2,872

297

769 815 807 779

3,169

73 % 75 % 75 % 71 %

73 %

$ 110 $ 116 $ 104 $ 155

$ 484

4 4 3 5

17

114 120 107 160

501

11 % 11 % 10 % 14 %

12 %

$ 883 $ 935 $ 914 $ 939

$ 3,670

$ 151 $ 143 $ 150 $ 151

$ 597

22 14 16 14

65

$ 173 $ 157 $ 166 $ 165

$ 662

16 % 14 % 15 % 15 %

15 %

$ 1,056 $ 1,092 $ 1,080 $ 1,104

$ 4,332

1Q 25 2Q 25 3Q 25 4Q 25

FY 25

$ 696 $ 740 $ 747 $ 755

72 71 69 77

$ 2,939

288

768 811 816 832

3,227

74 % 77 % 75 % 72 %

74 %

$ 109 $ 96 $ 107 $ 154

$ 465

3 5 4 4

17

112 101 111 158

482

11 % 10 % 10 % 14 %

11 %

$ 880 $ 912 $ 927 $ 990

$ 3,709

$ 142 $ 136 $ 147 $ 157

$ 581

19 11 10 12

53

$ 161 $ 147 $ 157 $ 169

$ 634

15 % 14 % 14 % 15 %

15 %

$ 1,041 $ 1,059 $ 1,084 $ 1,159

$ 4,343

1Q 26 2Q 26 3Q 26

FY 26

$ 726 $ 775 $ 764

71 77 77

$ 2,265

225

797 852 841

2,490

73 % 74 % 74 %

74 %

$ 118 $ 125 $ 102

$ 345

2 5 3

10

120 130 105

355

11 % 11 % 9 %

11 %

$ 917 $ 982 $ 946

$ 2,845

$ 151 $ 154 $ 155

$ 461

23 23 28

74

$ 174 $ 177 $ 183

$ 535

16 % 15 % 16 %

16 %

$ 1,091 $ 1,159 $ 1,129

$ 3,380

‌(in millions, except percentages) CONSUMABLES

Sequencing Consumables Microarrays Consumables

Total Consumables

% Revenue

INSTRUMENTS

Sequencing Instruments Microarrays Instruments

Total Instruments

% Revenue

TOTAL PRODUCT REVENUE SERVICE & OTHER

Sequencing Microarrays

Total Service & Other

% Revenue

TOTAL REVENUE (a)

1Q 24 2Q 24 3Q 24 4Q 24

FY 24

$ 698 $ 737 $ 741 $ 698

$ 2,872

110 116 104 155

484

151 143 150 151

597

$ 959 $ 996 $ 995 $ 1,004

$ 3,953

91 % 91 % 92 % 91 %

91 %

$ 71 $ 78 $ 66 $ 81

$ 297

4 4 3 5

17

22 14 16 14

65

$ 97 $ 96 $ 85 $ 100

$ 379

9 % 9 % 8 % 9 %

9 %

1Q 25 2Q 25 3Q 25 4Q 25

FY 25

$ 696 $ 740 $ 747 $ 755

$ 2,939

109 96 107 154

465

142 136 147 157

581

$ 947 $ 972 $ 1,001 $ 1,066

$ 3,985

91 % 92 % 92 % 92 %

92 %

$ 72 $ 71 $ 69 $ 77

$ 288

3 5 4 4

17

19 11 10 12

53

$ 94 $ 87 $ 83 $ 93

$ 358

9 % 8 % 8 % 8 %

8 %

1Q 26 2Q 26 3Q 26

FY 26

$ 726 $ 775 $ 764

$ 2,265

118 125 102

345

151 154 155

461

$ 995 $ 1,054 $ 1,021

$ 3,071

91 % 91 % 90 %

91 %

$ 71 $ 77 $ 77

$ 225

2 5 3

10

23 23 28

74

$ 96 $ 105 $ 108

$ 309

9 % 9 % 10 %

9 %

unaudited unaudited unaudited unaudited

3Q 26 3Q 26 Revenue

(in millions, except percentages)

Tariff Refunds (b)

Excluding Tariff Refunds (b)

SEQUENCING

Consumables Instruments Service & Other

Total Sequencing

% Revenue

MICROARRAYS

Consumables Instruments Service & Other

Total Microarrays

% Revenue

$ (28) $ 792

(4) 106

(3) 158

$ (35) $ 1,056

(2) 79

- 3

- 28

$ (2) $ 110

  1. Amounts include intercompany revenue between segments, which is eliminated in consolidation.

  2. Revenue was negatively impacted in 3Q 26 due to customer refunds accrued as a result of the benefit from IEEPA tariff refunds we recognized in the quarter. Amounts show revenue impact by product category.

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