Holding(s) in Company

About this update from Arecor Therapeutics Plc

TR-1: S tandard form for notification of major holdings   NOTIFICATION OF MAJOR HOLDINGS (to be sent to the relevant issuer and to the FCA in Microsoft Word format if possible) i 1a. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached ii : ARECOR THERAPEUTICS PLC 1b. Please indicate if the issuer is a non-UK issuer   (please mark with an "X" if appropriate) UK issuer 2. Reason for the notification (please mark the appropriate box or boxes with an "X") An acquisition or disposal of voting rights X An acquisition or disposal of financial instruments An event changing the breakdown of voting rights Other (please specify) iii : 3. Details of person subject to the notification obligation iv Name Lucius Cary City and country of registered office (if applicable) Oxford, UK 4. Full name of shareholder(s) (if different from 3.) v Name City and country of registered office (if applicable) 5. Date on which the threshold was crossed or reached vi : 14/11/25 6. Date on which issuer notified (DD/MM/YYYY): 14/11/25 7. Total positions of person(s) subject to the notification obligation % of voting rights attached to shares (total of 8. A) % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) Total of both in % (8.A + 8.B) Total number of voting rights held in issuer (8.A + 8.B) vii Resulting situation on the date on which threshold was crossed or reached 7.014% 7.014% 2,648,407   Position of previous notification (if applicable) 5.0% 5.0% 1,904,835   8. Notified details of the resulting situation on the date on which the threshold was crossed or reached viii A: Voting rights attached to shares Class/type of shares ISIN code (if possible) Number of voting rights ix % of voting rights Direct (DTR5.1) Indirect  (DTR5.2.1) Direct (DTR5.1) Indirect (DTR5.2.1) GB00BMWLM973     2,648,407   7.014% SUBTOTAL 8. A     2,648,407   7.014%     B 1: Financial Instruments according to DTR5.3.1R (1) (a) Type of financial instrument Expiration date x Exercise/ Conversion Period xi Number of voting rights that may be acquired if the instrument is exercised/converted. % of voting rights SUBTOTAL 8. B 1     B 2: Financial Instruments with similar economic effect according to DTR5.3.1R (1) (b) Type of financial instrument Expiration date x Exercise/ Conversion Period xi Physical or cash Settlement xii Number of voting rights % of voting rights   SUBTOTAL 8.B.2       9. Information in relation to the person subject to the notification obligation (please mark the applicable box with an "X") Person subject to the notification obligation is not controlled by any natural person or legal entity and does not control any other undertaking(s) holding directly or indirectly an interest in the (underlying) issuer xiii X Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entity (please add additional rows as necessary) xiv Name xv % of voting rights if it equals or is higher than the notifiable threshold % of voting rights through financial instruments if it equals or is higher than the notifiable threshold Total of both if it equals or is higher than the notifiable threshold   10. In case of proxy voting, please identify: Name of the proxy holder n/a The number and % of voting rights held n/a The date until which the voting rights will be held n/a 11. Additional information xvi Voting rights are held by AJ Bell   Place of completion London Date of completion 14 Nov 2025        

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