Director's Dealing

Proteome Sciences Plc ("Proteome Sciences" or "the Company") DIRECTOR'S DEALING Proteome Sciences announces that it has received notification today from James Malthouse, an Executive Director of the Company, that 50,000 ordinary shares that were held in his late wife's name have been transferred for a nil consideration to his adult daughter. As a consequence of this, the shares no longer form part of his beneficial holdings as defined by the AIM rules. James Malthouse now has an interest in 250,000 Ordinary Shares of the issued ordinary share capital of the Company. Enquiries Proteome Sciences plc Christopher Pearce, Chief Executive Officer Email: christopher.pearce@proteomics.com James Malthouse, Finance Director Email: james.malthouse@proteomics.com Tel: +44 (0)1932 865065 Public Relations for Proteome Sciences IKON Associates Adrian Shaw Tel: +44 (0)1483 535102 Mobile: +44 (0)797 9900733 Email: adrian@ikonassociates.com Coast Communications Matt Baldwin Tel: +44 (0) 1233 503200 Mobile: +44 (0) 7930 439739 Email: matt@coastcommunications.com