Business

Director/PDMR Shareholding – Share purchase

AOTI Inc. announced that Senior Independent Director Richard Cotton and Mrs Jane Cotton-Hall purchased a total of 49,110 common shares for an aggregate price of approximately 60.78 pence per share, with transactions occurring on 17 and 18 June 2026. Following these purchases, Mr Cotton's beneficial holding, including Mrs Cotton-Hall's, increased to 264,540 common shares, representing approximately 0.25% of the Company's issued share capital. Disclaimer*

Aoti, Inc.June 19, 20264
Director/PDMR Shareholding – Share purchase

About this update from Aoti, Inc.

19 June 2026   AOTI Inc. (the "Company")   Director/PDMR Shareholding - Share purchase   The Company was informed on 18 June 2026 that Mr Richard Cotton, Senior Independent Director of the Company, and Mrs Jane Cotton-Hall, bought a total of 49,110 common shares of $0.00001 in the capital of the Company ("Common Shares") through the purchase of 30,000 Common Shares at 60 pence per share on 17 June 2026 and 19,110 Common Shares at 62 pence per share on 18 June 2026.   Following the purchases, Mr Cotton's beneficial holding (including that of Mrs Cotton-Hall) and total interest in the Company has increased to 264,540 Common Shares, representing approximately 0.25% of the Company's issued share capital.   The below notification, made in accordance with Article 19 of the Market Abuse Regulation (EU) 596/2014 as it forms part of domestic law by virtue of the European Union (Withdrawal) Act 2018, provides further detail.   Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them   1   Details of the person discharging managerial responsibilities / person closely associated   a)   Name   Richard Cotton / Jane Cotton-Hall 2   Reason for the notification   a)   Position/status   Senior Independent Director / PCA   b)   Initial notification /Amendment   Initial notification 3   Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor   a)   Name   AOTI Inc. b)   LEI   213800ZGCNDSTWIRK687 4   Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted   a)   Description of the financial instrument, type of instrument   Identification code   Common shares of $0.00001 each     ISIN: US03690C1027 b)   Nature of the transaction     Purchase of Common Shares by Mr Cotton and Mrs Cotton-Hall on 17 June 2026 and 18 June 2026   c)   Price(s) and volume(s) Date Price(s) Volume(s) 17 June 2026 60p 15,000 17 June 2026 60p 15,000 18 June 2026 62p 9,555 18 June 2026 62p 9,555 d)   Aggregated information   - Aggregated volume   - Price       49,110   60.7783p e)   Date of the transaction   17 June 2026 and 18 June 2026 f)   Place of the transaction   London Stock Exchange   For further information please contact: AOTI, INC. Dr. Mike Griffiths, Chief Executive Officer Jayesh Pankhania, Chief Financial Officer     +44 (0)20 3727 1000 [email protected] Peel Hunt LLP (Nominated Adviser and Broker) Dr. Christopher Golden, James Steel     +44 (0)20 7418 8900 Panmure Liberum Limited (Joint Broker) Emma Earl, Will Goode, Mark Rogers Rupert Dearden   +44 (0)20 3100 2000   FTI Consulting (Financial PR & IR) Ben Atwell, Simon Conway, Natalie Garland-Collins  +44 (0)20 3727 1000 [email protected]   ABOUT AOTI, INC.   AOTI, INC. was founded in 2006 and is based in Oceanside, California, US and Galway, Ireland, providing innovative solutions to resolve severe and chronic wounds worldwide. Its products reduce healthcare costs and improve the quality of life for patients with these debilitating conditions. The Company's patented non-invasive Topical Wound Oxygen (TWO 2 ® ) therapy has demonstrated in differentiating, robust, double-blinded randomised controlled trials (RCT) and real-world evidence (RWE) studies to more durably reduce the recurrence of Diabetic Foot Ulcers (DFUs), resulting in an unprecedented 88 per cent reduction in hospitalisations and 71 per cent reduction in amputations over 12 months. TWO 2 ® therapy can be administered by the patient at home, improving access to care and enhancing treatment compliance. TWO 2 ® therapy has received regulatory clearance from the US (FDA), Europe (CE Mark), UK (MHRA), Health Canada, the Chinese National Medical Products Administration, Australia (TGA) and in Saudi Arabia. TWO 2 ® therapy has also recently received positive coverage recommendations from the Federal Joint Committee (G-BA) in Germany and National Institute for Health and Care Excellence (NICE) in the United Kingdom. Also see www.aotinc.net  

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