D.western Therapeutics Institute, Inc.TSE: 4576

FY12/22 Financial Results Briefing Materials

· Issued by D.western Therapeutics Institute, Inc.

FY12/22

Financial Results Briefing Materials

February 13, 2022

D. Western Therapeutics Institute, Inc.

Stock Code: 4576

Copyright D. Western Therapeutics Institute, Inc. All Rights Reserved.

Table of Contents

  1. FY12/22 Financial Results
  2. Progress of Business in FY12/22
  3. FY12/23 Forecast

(Reference) Business Overview

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1. FY12/22 Financial Results

January 1-December 31, 2022

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Consolidated Statement of Income (YoY comparison)

726

(JPYmn)

565

414

448

469

316

249

256

20

27

Loss attributable to

Net sales

Cost of sales SG&A expenses(R&D expenses)

(Other)

Operating loss

Ordinary loss

owners of parent

(148)

(171)

(159)

FY12/21

FY12/22

(305)

(295)

(429)

Net sales

  • Royalty revenue grew 30.1% YoY, because sales of DW-1002 increased 22.2% YoY in Europe, US, and Canada, with a favorable forex impact (+7.8% YoY).
  • Net sales rose 8.1% YoY, underpinned by milestone revenue accompanying the start of domestic Phase I study of DW- 1001 and receiving payment on transfer of exclusive enforcement rights to subsidiary JIT's corneal endothelium therapeutic agents.

R&D expenses

  • R&D expenses rose 48.5% YoYdue to increased spending on development of H-1337 (Phase IIb study in the US) and DWR-2206.

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Consolidated Statement of Income (vs. full-year forecast)

(JPYmn)

FY12/21

FY12/22

FY results

FY results

YoY change

FY forecast

FY forecast

% of initial

Primary factors

(out Feb.10)

(out Nov.18)

forecast

• Royalty revenue from DW-1002 far exceeded initial

Net sales

414

448

33

370

440

121.1%

forecast

• Received one-time payment for transfer of exclusive

enforcement rights to subsidiary JIT's corneal

endothelium therapeutic agents.

SG&A expenses

565

726

160

R&D expenses

316

469

153

790

Undisclosed

59.4%

• Reduced due to the development cost of H-1337

being lower than expected

Other SG&A

249

256

7

expenses

Operating loss

(171)

(305)

(134)

(690)

(400)

-

Ordinary loss

(159)

(295)

(136)

(700)

(390)

-

Loss attributable

(148)

(429)

(280)

(670)

(380)

-

to owners of

parent

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