This announcement replaces the announcement released 26 February at 09.00. In
the announcement released at 09.00, the Sanofi-Aventis interest holdings was
incorrectly stated as having crossed the 9% threshold. The correct threshold
crossed is 10%
For filings with the FSA include the annex
For filings with issuer exclude the annex
TR-1: Notifications of Major Interests in Shares
1. Identity of the issuer or the underlying issuer of existing
shares to which voting rights are attached:
Proteome Sciences plc
2. Reason for notification [Yes/No]
An acquisition or disposal of voting rights Yes
An acquisition or disposal of financial instruments which No
may result in the
acquisition of shares already issued to which voting rights
are attached
An event changing the breakdown of voting rights No
Other (please specify): No
3. Full name of person(s) subject to Sanofi-Aventis Deutschland GmbH
notification
obligation:
4. Full name of shareholder(s) (if
different from 3):
5. Date of transaction (and date on 24 February 2009
which the
threshold is crossed or reached if
different):
6. Date on which issuer notified: 25 February 2009
7. Threshold(s) that is/are crossed or 10.00%
reached:
8: Notified Details
A: Voting rights attached to shares
Class/type of Situation previous to Resulting situation after
shares the triggering the triggering transaction
transaction
If possible Number of Number of Number of Number of Percentage of
use shares voting shares voting rights voting rights
ISIN code rights
Direct Indirect Direct Indirect
GB003104196 13,663,380 13,663,380 12,286,187 12,286,187 9.25%
B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ No. of voting Percentage of
financial date conversion rights that may be voting rights
instrument period/date acquired (if the
instrument
exercised/
converted)
Total (A+B)
Number of voting rights Percentage of voting rights
12,286,187 9.25%
9. Chain of controlled undertakings through which the voting rights and /or the
financial instruments are effectively held, if applicable:
Proxy Voting:
10. Name of proxy holder:
11. Number of voting rights proxy
holder will cease to hold:
12. Date on which proxy holder will
cease to hold voting rights:
13. Additional information:
14 Contact name: James Malthouse
15. Contact telephone name: +44 1932 865065
D