Chiome Bioscience Inc.TSE: 4583

Supplementary Information for Financial Results FY12/21

· Issued by Chiome Bioscience Inc.

Supplementary Information for Financial Results FY12/21

Feb. 14, 2022

To accelerate drug discovery and development of mAb for therapeutics to overcome current medical unmet-needs

Chiome Bioscience Inc.

Agenda

1.Overview of FY12/21 "Financial results"

2.Overview of FY12/21 "Operation highlights"

Appendix.

Corporate information

Pipeline information

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Overview of

FY12/21 "Financial results"

Copyright © 2017 Chiome Bioscience Inc. All Rights Reserved.

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Financial results: Profit and Loss

(JPY in millions)

FY2020

FY2021

Increase

Main reasons for increase / decrease

(decrease)

Net sales

480

712

232

Drug Discovery &

3

103

99

• Upfront payment of the License

Development

Agreement with Shanghai Henlius Biotech,

Inc. for LIV-2008/2008b

Drug Discovery

477

609

132

• Growth in business with domestic

Support

pharmaceutical companies

COS/SGA

1,764

2,047

282

R&D Expense

1,156

1,312

155

• Cost of the study drug manufacturing in

CBA-1535 program

Other costs

607

735

127

• Up in material costs due to increased

business transactions

Operating Loss

(1,283)

(1,334)

(50)

Ordinary Loss

(1,291)

(1,329)

(37)

• Revenue from AMED grants

Net Loss

(1,293)

(1,479)

(186)

• Loss on devaluation of investment

securities

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Financial results: Balance Sheet

(JPY in millions)

As of Dec. 31, 2020

As of Dec. 31, 2021

Current assets

3,248

2,216

(Cash on hand in banks)

2,686

1,790

(Other current assets)

562

425

①

Non-current assets

246

122

Total assets

3,494

2,339

Current Liabilities

342

392

Non-current liabilities

41

53

Total liabilities

384

446

Total net assets

3,109

1,893

②

Total liabilities and net assets

3,494

2,339

Explanation of balance sheet

① Non-current assets decreased due to impairment of investment securities of investees. ②Retained earnings -1,479 million yen

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