CHINA PHARMA HOLDINGS, INC. : Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Financial Statements and Exhibits (form 8-K)

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Item 1.01. Entry into a Material Definitive Agreement. On November 17, 2021 , China Pharma Holdings, Inc. (the "Company") entered into a Securities Purchase Agreement (the "Agreement") pursuant to which the Company issued an unsecured convertible promissory note (the "Note") to an institutional accredited investor Streeterville Capital, LLC ("Investor"). The Note shall mature fifteen (15) months after the purchase price of the Note is delivered from the Investor to the Company (the "Purchase Price Date"). The Note has the original principal amount of $5,250,000 and Investor gave consideration of $5,000,000 , reflecting original issue discount of $250,000 . The transaction contemplated under the Agreement was closed on November 19, 2021 and the Company anticipates using the proceeds for general working capital purposes. Interest accrues on the outstanding balance of the Note at 5% per annum. Upon the occurrence of an Event of Default as defined in the Note, interest accrues at the lesser of 22% per annum or the maximum rate permitted by applicable law. In addition, upon any Event of Default, the Investor may accelerate the outstanding balance payable under the Note, which will increase automatically upon such acceleration by 15% or 5%, depending on the nature of the Event of Default. Pursuant to the terms of the Agreement and the Note, the Company must obtain Investor's consent for certain fundamental transactions such as consolidation, merger with or into another entity (excerpt for a reincorporation merger), disposition of substantial assets, change of control, reorganization or recapitalization. Any occurrence of a fundamental transaction without Investor's prior written consent will be deemed an Event of Default. Investor may redeem all or any part the outstanding balance of the Note, subject to $500,000 per calendar month, at any time after one hundred twenty-one (121) days from the Purchase Price Date upon three trading days' notice, in cash or converting into shares of the Company's common stock, par value $0.001 ("Common Stock") at a price equal to 85% multiplied by the lowest daily VWAP during the ten (10) trading days immediately preceding the applicable redemption conversion, subject to certain adjustments and ownership limitations specified in the Note. The Note provides for liquidated damages upon failure to comply with any of the terms or provisions of the Note. The Company may prepay the outstanding balance of the Note with the Investor's consent. Pursuant to the terms of the Agreement, the Company will reserve 30,000,000 shares of Common Stock from its authorized and unissued Common Stock to provide for all issuances of Common Stock under the Note (the "Share Reserve"). The Company further agrees to add additional shares of Common Stock to the Share Reserve in increments of 1,000,000 shares under certain circumstances. The Company relied on the exemption from registration afforded by Section 4(a)(2) of the Securities Act of 1933 and Regulation D promulgated thereunder in connection with the issuance and sale of the Note and underlying shares of Common Stock. The underlying shares of Common Stock in connection with the issuance and sale of the Note may be issued pursuant to the Company's effective shelf registration statement. The Company agreed, within thirty (30) days of the issuance and sale of the Note, to file with the Securities and Exchange Commission a prospectus supplement pursuant to Rule 424(b) of the Securities Act registering $5,000,000 in Common Stock for the benefit of Investor. The foregoing description is qualified in its entirety by reference to the full text of the Note and the Agreement, a copy of each of which is filed as Exhibit 4.1 and Exhibit 10.1 hereto, and each of which is incorporated herein by reference. Item 2.03. Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. The information in Item 1.01 is incorporated herein by reference. Item 9.01 Financial Statements and Exhibits. (d) Exhibits. The following is filed as an exhibit to this report: Exhibit Number Exhibit 4.1 Convertible Promissory Note dated November 17, 2021 10.1 Securities Purchase Agreement between China Pharma Holdings, Inc. and Streeterville Capital, LLC dated November 17, 2021 104 Cover Page Interactive Data File (embedded within the Inline XBRL document) 1 © Edgar Online, source Glimpses

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