Charles River Accelerates Digital Pathology with AI-Powered End-to-End Workflow

About this update from Charles River Laboratories International, Inc.

WILMINGTON, Mass., May 11, 2026--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL) today announced continued momentum in its digital pathology platform, delivering an end-to-end, AI-enabled workflow that significantly accelerates study timelines, and enhances pathologist efficiency, and supports the reduction of animal use in nonclinical research where scientifically appropriate. By fully integrating digital pathology across the histology and pathology workflow, Charles River is committed to cutting at least one week from standard pathology timelines while maintaining Good Laboratory Practice (GLP) rigor and regulatory readiness. These efficiency gains are driven by the combination of a fully integrated histology laboratory information management system (LIMS), AI-powered slide quality control (QC), and validated digital primary pathology reviews. "Digital pathology isn’t just about digitizing slides; it is about reengineering the entire workflow," said Danielle Brown, Digital Products Leader, Charles River. "By applying AI at critical bottlenecks and grounding our models in Charles River’s unmatched pathology expertise and image libraries, we are delivering faster, more scalable, and more insightful pathology for our clients." Eliminating Bottlenecks Across the Histopathology WorkflowCharles River’s digital pathology workflow addresses one of the most time- and labor-intensive steps in histopathology: manual slide quality control. Traditionally, highly-trained technicians had to individually review every slide, creating delays before slides ever reached a pathologist. Through an AI-powered QC platform, developed in partnership with Deciphex, Charles River is systematically eliminating this bottleneck through a phased approach: Once fully deployed, this automated QC capability will remove an entire manual step from the histology process, shortening turnaround times while allowing skilled technical staff to focus on higher value activities. Charles River is also deploying a fully integrated end-to-end histology tracking and management system, Prima, which will create a completely seamless, paperless histology workflow to enhance quality and maximize efficiency. Validated Digital Reviews and AI-Driven Decision SupportIn parallel, Charles River has implemented GLP-validated digital primary pathology reviews, elim...

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