Change in use of proceeds from the global offering

派格生物醫藥（杭州）股份有限公司 (A joint stock company incorporated in the People’s Republic of China with limited liability) (Stock Code: 2565) CHANGE IN USE OF PROCEEDS FROM THE GLOBAL OFFERING Reference is made to the prospectus issued by PegBio Co., Ltd. (the “Company”, together with its subsidiaries, the “Group”) dated May 19, 2025 (the “Prospectus”) in relation to the proposed use of net proceeds from the