Thalia Therapeutics PlcLSE: THAT

CEO Interview

· Investegate

2 June 2026

Thalia Therapeutics plc

("Thalia" or the "Company")

CEO Interview: Building a Differentiated RNA Therapeutics Company

Thalia Therapeutics plc (AIM: THAT), a biotechnology company developing innovative RNA therapeutics, is pleased to announce the release of a new video interview with Chief Executive Officer, Dr David Solomon, speaking with BioHub.

In the interview, Dr Solomon discusses the significant room for innovation in RNA therapeutics and how Thalia is positioning itself in this rapidly expanding market to develop differentiated next-generation RNA Therapeutics. 

In particular, the discussion also explores Thalia's differentiated approach to treating cardiovascular disease, with a long-acting preclinical candidate that addresses two independent risk factors of cardiovascular disease simultaneously, PCSK9 and Lp(a), offering the potential for additive or synergistic benefits.

The interview is available to watch via the Company's website at: https://investors.thaliatx.com/activity-updates/epjN8P-thalia-tx-on-biohub

There is growing interest in genetically targeted approaches to cardiovascular disease and PCSK9-targeted therapies, as reflected in recent clinical research published in The New England Journal of Medicine here: https://www.nejm.org/doi/10.1056/NEJMoa2601283

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For more information please contact:

Thalia Therapeutics plc

Dr David H Solomon, Chief Executive Officer

Via Thalia Investor Hub

https://investors.thaliatx.com/link/eNbqpe

SP Angel Corporate Finance LLP

Nominated Adviser and Joint Broker

Matthew Johnson/Jen Clarke (Corporate Finance)

Vadim Alexandre/Abigail Wayne/Rob Rees (Corporate Broking)

Tel: +44 (0)20 3470 0470

Turner Pope Investments (TPI) Limited

Joint Broker

Andy Thacker

Guy McDougall 

Tel: +44 (0)20 3657 0050

Northstar Communications

Investor relations and Communications

Sarah Hollins

Cohesion Bureau

Investor relations and Communications

Mary-Ann Chang

Tel: +44 (0)20 7183 2463

Tel: +44 (0)7483 284853

About Thalia Therapeutics plc

Thalia Therapeutics is a pre-clinical biotechnology company developing innovative RNA-based therapeutics and delivery technologies in oncology and cardiovascular disease. With a growing, differentiated pipeline, de-risked by validated therapeutic targets, we aim to treat diseases at the source by silencing or modifying the genes that cause or contribute to them.

Our preclinical bispecific siRNA is a potentially long-acting treatment for atherosclerotic cardiovascular disease, which addresses two independent drivers of cardiovascular risk. Our proprietary delivery technology, Nuvec®, offers the potential to overcome the fundamental challenges of RNA delivery, enabling targeted, scalable RNA therapeutics.

For further information visit www.thaliatx.com

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