Business
CareDx Announces Third Quarter 2025 Financial Results
Total Revenue of $100 Million Increased 21% Year-Over-Year Grew Testing Services Volume to Approximately 50,300, Increase of 13% Year-Over-Year Raised 2025
About this update from Caredx, Inc.
Total Revenue of $100 Million Increased 21% Year-Over-Year Grew Testing Services Volume to Approximately 50,300, Increase of 13% Year-Over-Year Raised 2025 Revenue Guidance to $372 Million to $376 Million BRISBANE, Calif. --(BUSINESS WIRE)-- CareDx, Inc. (Nasdaq: CDNA) — The Transplant Company — a leading precision medicine company focused on the discovery, development and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers, today reported financial results for the third quarter ended September 30, 2025 . Third Quarter 2025 Financial Highlights Revenue of $100.1 million , an increase of 21% year-over-year Testing services revenue of $72.2 million , an increase of 19% year-over-year Testing services volume of 50,300, an increase of 13% year-over-year GAAP net income of $1.7 million , compared to a GAAP net loss of $10.6 million in the third quarter of 2024 Adjusted EBITDA of $15.3 million , compared to $6.9 million in the third quarter of 2024 Cash, cash equivalents and marketable securities of $194.2 million as of September 30, 2025 , net of a $25.6 million share repurchase carried out during the quarter; no debt outstanding as of September 30, 2025 Raised 2025 revenue guidance to $372 million to $376 million and raised 2025 adjusted EBITDA guidance to $35 million to $39 million Recent Business Highlights Appointed Suresh Gunasekaran , president and CEO of UCSF Health , an internationally renowned health system executive, to the CareDx Board of Directors Appointed Jeff Teuteberg , MD, a leader in transplant medicine with a track record of clinical innovation, research, and patient advocacy, as Chief Medical Officer Published second SHORE study, validating AlloSure Heart as a reliable biomarker for detecting antibody-mediated rejection (AMR) in heart transplant patients, reinforcing that HeartCare can detect both AMR and ACR Introduced HistoMap Kidney, a tissue-based gene expression profiler that integrates advanced histopathology with molecular insights to support more precise and timely decisions for patients Submitted extensive, evidence-based comment letter intended to inform final draft of LCD policy Completed first Epic Aura implementation and anticipate initiating approximately 20 implementations by year-end 2025 Launched AlloSeq Tx11, a next-generation HLA typing solution with enhanced Class II coverage and expanded non-HLA markers to support broader transplant risk profiling Introduced Score 7.0, modernized analysis software for QTYPE built for scalability and regulatory alignment that supports future ABO typing and IVDR compliance “We achieved record-setting third quarter 2025 financial results, a testament to our market leadership that has been established through a deep commitment to innovation and transplant patient care,” said John W. Hanna , President and CEO of CareDx . “Our strategy to extend that leadership and deliver long-term profitable growth is guided by putting our customers at the center of everything we do, and we believe that strategy is working.” Q3 2025 Financial Results Total revenue was $100.1 million compared to $82.9 million in the third quarter of 2024, an increase of 21%. Testing services revenue was $72.2 million , compared to $60.8 million in the third quarter of 2024, an increase of 19%. Patient and Digital Solutions revenue was $15.4 million , compared to $11.9 million in the third quarter of 2024, an increase of 30%. Product revenue was $12.5 million , an increase of 22% compared to $10.2 million in the third quarter of 2024. GAAP net income was $1.7 million compared to GAAP net loss of $10.6 million in the third quarter 2024. Basic and diluted GAAP net income per share was $0.03 compared to basic and diluted GAAP net loss per share of $0.20 in the third quarter of 2024. Non-GAAP net income was $14.9 million compared to $8.0 million in the third quarter of 2024. Diluted non-GAAP net income per share was $0.28 compared to $0.14 in the third quarter of 2024. Adjusted EBITDA was $15.3 million compared to $6.9 million in the third quarter of 2024. 2025 Guidance For the full year 2025, CareDx now expects revenue to be in the range of $372 million to $376 million , compared to the $367 million to $373 million range that was previously disclosed. The Company now expects full year 2025 adjusted EBITDA to be in the range of $35 million to $39 million , compared to the $29 million to $33 million range that was previously disclosed. About CareDx – The Transplant Company CareDx, Inc. , headquartered in Brisbane, California , is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers testing services, products, and digital healthcare solutions along the pre- and post-transplant patient journey and is the leading provider of genomics-based information for transplant patients. For more information, please visit: www.CareDx.com . Forward Looking Statements This press release includes forward-looking statements, including expectations regarding the achievement of CareDx’s financial and operational goals and its expectations and prospects for 2025. These forward-looking statements are based upon information that is currently available to CareDx and its current expectations, speak only as of the date hereof, and are subject to numerous risks and uncertainties, all of which are difficult to predict and many of which are beyond CareDx’s control, that could cause the actual results to differ materially from those projected, including general economic and market factors, and global economic and marketplace uncertainties, among others discussed in CareDx’s filings with the Securities and Exchange Commission (the “SEC”), including, but not limited to, the Annual Report on Form 10-K for the fiscal year ended December 31, 2024 filed by CareDx with the SEC on February 28, 2025 , and other reports that CareDx has filed with the SEC . Any of these may cause CareDx’s actual results, performance, or achievements to differ materially and adversely from those anticipated or implied by CareDx’s forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements. CareDx expressly disclaims any obligation, except as required by law, or undertaking to update or revise any such forward-looking statements, whether as a result of new information, future events or otherwise. Use of Non-GAAP Financial Measures CareDx has presented in this release certain financial information in accordance with U.S. Generally Accepted Accounting Principles (“GAAP”) and also on a non-GAAP basis, including non-GAAP cost of testing services, non-GAAP cost of product, non-GAAP cost of patient and digital solutions, non-GAAP research and development expenses, non-GAAP sales and marketing expenses, non-GAAP general and administrative expenses, non-GAAP other income, net, non-GAAP income tax expense, non-GAAP gross profit, non-GAAP gross margin (%), non-GAAP operating expenses, non-GAAP net income, non-GAAP basic and diluted net income per share and adjusted EBITDA. These non-GAAP financial measures are not meant to be considered superior to or a substitute for financial measures calculated in accordance with GAAP, and investors are cautioned that there are material limitations associated with the use of non-GAAP financial measures as an analytical tool. We define non-GAAP net income and per share results as the GAAP net income (loss) and per share results excluding the impacts of stock-based compensation expense; acquisition-related amortization of purchased intangible assets and related tax effects; costs involved with completing an acquisition; changes in estimated fair value of contingent consideration; litigation settlement expense; transformational initiative costs; and certain other charges presented in the reconciliation in this release. We define adjusted EBITDA as non-GAAP net income before interest income, income tax expense, depreciation expense and other (income) expense, net. We are presenting these non-GAAP financial measures to assist investors in assessing our operating results through the eyes of management and because we believe that these measures provide an additional tool for investors to use in comparing our core business operating results over multiple periods where certain items may vary independent of business performance. Management believes this non-GAAP information is useful for investors, when considered in conjunction with CareDx’s GAAP financial statements, because management uses such information internally for its operating, budgeting and financial planning purposes. Non-GAAP information is not prepared under a comprehensive set of accounting rules and should only be used to supplement an understanding of CareDx’s operating results as reported under GAAP. These non-GAAP financial measures should not be considered in isolation from, or as a substitute for, financial information prepared in accordance with GAAP. These non-GAAP financial measures are not necessarily comparable to similarly titled measures presented by other companies. A reconciliation between GAAP and non-GAAP financial information is provided immediately following the financial tables. A reconciliation of the forecasted range for adjusted EBITDA for 2025 is not included in this release due to the number of variables in the projected range and because we are currently unable to quantify accurately certain amounts that would be required to be included in the U.S. GAAP measure or the individual adjustments for such reconciliation. CareDx, Inc. Condensed Consolidated Statements of Operations (Unaudited) (In thousands, except share and per share data) Three Months Ended September 30 , 2025 2024 Revenue: Testing services revenue $ 72,168 $ 60,807 Product revenue 12,478 10,212 Patient and digital solutions revenue 15,409 11,864 Total revenue 100,055 82,883 Operating expenses: Cost of testing services 14,705 13,447 Cost of product 5,629 6,212 Cost of patient and digital solutions 10,320 7,913 Research and development 16,769 17,486 Sales and marketing 24,449 19,802 General and administrative 28,429 31,744 Total operating expenses 100,301 96,604 Loss from operations (246 ) (13,721 ) Other income: Interest income, net 2,013 3,001 Other (expense) income, net (107 ) 283 Total other income 1,906 3,284 Income (loss) before income taxes 1,660 (10,437 ) Income tax benefit (expense) 15 (200 ) Net income (loss) $ 1,675 $ (10,637 ) Net income (loss) per share: Basic $ 0.03 $ (0.20 ) Diluted $ 0.03 $ (0.20 ) Weighted-average shares used to compute net income (loss) per share: Basic 52,507,582 52,903,338 Diluted 53,736,790 52,903,338 CareDx, Inc. Condensed Consolidated Balance Sheets (Unaudited) (In thousands) September 30, 2025 December 31, 2024 Assets Current assets: Cash and cash equivalents $ 91,435 $ 114,689 Marketable securities 102,782 145,964 Accounts receivable 47,844 64,605 Inventory 28,328 19,503 Prepaid and other current assets 29,891 7,071 Total current assets 300,280 351,832 Property and equipment, net 30,845 33,552 Operating leases right-of-use assets 24,047 24,340 Intangible assets, net 33,446 38,184 Goodwill 40,336 40,336 Restricted cash 551 585 Other assets 2,802 2,221 Total assets $ 432,307 $ 491,050 Liabilities and stockholders’ equity Current liabilities: Accounts payable $ 11,597 $ 7,686 Accrued compensation 23,237 38,333 Accrued litigation settlement expense 20,250 — Accrued and other liabilities 43,960 43,352 Total current liabilities 99,044 89,371 Deferred tax liability 117 164 Contingent consideration 160 174 Operating lease liability, less current portion 21,212 22,263 Other liabilities 634 645 Total liabilities 121,167 112,617 Commitments and contingencies Stockholders’ equity: Common stock 51 51 Additional paid-in capital 1,036,091 1,013,193 Accumulated other comprehensive loss (5,955 ) (8,569 ) Accumulated deficit (719,047 ) (626,242 ) Total stockholders’ equity 311,140 378,433 Total liabilities and stockholders’ equity $ 432,307 $ 491,050 CareDx, Inc. Reconciliation of GAAP to Non-GAAP Financial Measures (Unaudited) (In thousands) Three Months Ended September 30 , 2025 2024 Cost of testing services reconciliation: GAAP cost of testing services $ 14,705 $ 13,447 Stock-based compensation expense (299 ) (418 ) Restructuring costs (120 ) — Acquisition related-amortization of purchased intangibles (348 ) (329 ) Non-GAAP cost of testing services $ 13,938 $ 12,700 Cost of product reconciliation: GAAP cost of product $ 5,629 $ 6,212 Stock-based compensation expense (51 ) (234 ) Acquisition related-amortization of purchased intangibles (447 ) (419 ) Restructuring costs (11 ) — Non-GAAP cost of product $ 5,120 $ 5,559 Cost of patient and digital solutions reconciliation: GAAP cost of patient and digital solutions $ 10,320 $ 7,913 Stock-based compensation expense (118 ) (326 ) Acquisition related-amortization of purchased intangibles (152 ) (170 ) Restructuring costs 8 — Non-GAAP cost of patient and digital solutions $ 10,058 $ 7,417 Research and development expenses reconciliation: GAAP research and development expenses $ 16,769 $ 17,486 Stock-based compensation expense (1,146 ) (1,775 ) Restructuring costs (174 ) — Non-GAAP research and development expenses $ 15,449 $ 15,711 Sales and marketing expenses reconciliation: GAAP sales and marketing expenses $ 24,449 $ 19,802 Stock-based compensation expense (1,782 ) (2,786 ) Acquisition related-amortization of purchased intangibles (655 ) (634 ) Transformational initiative costs* (183 ) — Restructuring costs (233 ) — Non-GAAP sales and marketing expenses $ 21,596 $ 16,382 General and administrative expenses reconciliation: GAAP general and administrative expenses $ 28,429 $ 31,744 Stock-based compensation expense (5,022 ) (11,384 ) Change in estimated fair value of contingent consideration — (232 ) Transformational initiative costs* (341 ) — Impairment of intangible asset (2,258 ) — Non-GAAP general and administrative expenses $ 20,808 $ 20,128 Total other income reconciliation: GAAP other income $ 1,906 $ 3,284 Non-GAAP other income $ 1,906 $ 3,284 Income tax benefit (expense) reconciliation: GAAP income tax benefit (expense) $ 15 $ (200 ) Tax effect related to amortization of purchased intangibles (111 ) (102 ) Non-GAAP income tax expense $ (96 ) $ (302 ) * Transformational initiative costs consist of consulting expenses which relate to our ongoing transformation strategy that we have undertaken as a series of initiatives focused on operational excellence, enterprise-wide efficiency, and long-term strategic growth, including rebranding costs. CareDx, Inc. GAAP and Non-GAAP Operating Expenses (Unaudited) (In thousands) Three Months Ended September 30 , 2025 2024 GAAP operating expenses: Research and development $ 16,769 $ 17,486 Sales and marketing 24,449 19,802 General and administrative 28,429 31,744 Total GAAP operating expenses $ 69,647 $ 69,032 Non-GAAP operating expenses: Research and development $ 15,449 $ 15,711 Sales and marketing 21,596 16,382 General and administrative 20,808 20,128 Total Non-GAAP operating expenses $ 57,853 $ 52,221 CareDx, Inc. Reconciliation of GAAP to Non-GAAP Gross Profit and Gross Margin (Unaudited) (In thousands, except percentages) Three Months Ended September 30 , 2025 2024 GAAP total revenue $ 100,055 $ 82,883 GAAP cost of sales 30,654 27,572 GAAP gross profit 69,401 55,311 GAAP gross margin % 69 % 67 % Stock-based compensation expense 468 978 Restructuring costs 123 — Acquisition related-amortization of purchased intangibles 947 918 Non-GAAP gross profit $ 70,939 $ 57,207 Non-GAAP gross margin % 71 % 69 % CareDx, Inc. Reconciliation of GAAP to Non-GAAP Financial Measures (Unaudited) (In thousands, except share and per share data) Three Months Ended September 30 , 2025 2024 GAAP net income (loss) $ 1,675 $ (10,637 ) Stock-based compensation expense 8,418 16,923 Acquisition related-amortization of purchased intangibles 1,602 1,552 Change in estimated fair value of contingent consideration — 232 Tax effect related to amortization of purchased intangibles (111 ) (102 ) Impairment of intangible asset 2,258 — Transformational initiative costs* 524 — Restructuring costs 530 — Non-GAAP net income $ 14,896 $ 7,968 GAAP basic net income (loss) per share $ 0.03 $ (0.20 ) GAAP diluted net income (loss) per share $ 0.03 $ (0.20 ) Non-GAAP basic net income per share $ 0.28 $ 0.15 Non-GAAP diluted net income per share $ 0.28 $ 0.14 Shares used in computing non-GAAP basic net income per share 52,507,582 52,903,338 Shares used in computing non-GAAP diluted net income per share 53,736,790 57,699,624 * Transformational initiative costs consist of consulting expenses which relate to our ongoing transformation strategy that we have undertaken as a series of initiatives focused on operational excellence, enterprise-wide efficiency, and long-term strategic growth, including rebranding costs. CareDx, Inc. Reconciliation of Non-GAAP to Adjusted EBITDA (Unaudited) (In thousands) Three Months Ended September 30 , 2025 2024 GAAP net income (loss) $ 1,675 $ (10,637 ) Stock-based compensation expense 8,418 16,923 Acquisition related-amortization of purchased intangibles 1,602 1,552 Change in estimated fair value of contingent consideration — 232 Tax effect related to amortization of purchased intangibles (111 ) (102 ) Impairment of intangible asset 2,258 — Transformational initiative costs* 524 — Restructuring costs 530 — Non-GAAP net income 14,896 7,968 Interest income (2,013 ) (3,001 ) Income tax expense 96 302 Depreciation expense 2,213 1,919 Other expense (income), net 107 (283 ) Adjusted EBITDA $ 15,299 $ 6,905 * Transformational initiative costs consist of consulting expenses which relate to our ongoing transformation strategy that we have undertaken as a series of initiatives focused on operational excellence, enterprise-wide efficiency, and long-term strategic growth, including rebranding costs. View source version on businesswire.com : https://www.businesswire.com/news/home/20251104307786/en/ CareDx, Inc. Media Relations Natasha Moshirian Wagner [email protected] Investor Relations Tina Jacobsen [email protected] Source: CareDx, Inc.