Alcon AgSIX: ALC

J.P. Morgan Healthcare Conference Presentation

· Issued by Alcon Ag
J.P. Morgan Healthcare Conference David J. Endicott

Chief Executive Officer January 13th, 2026



Alcon at a glance


Alcon

at a glance

Alcon sales:

$9.8b (2024)

$7.6b (YTD Q3-25)

Alcon offers the widest array of surgical equipment, ocular health products and contact lenses in the industry. We touch millions of lives in over 140 countries.

Our Surgical products rank number one in market position globally. Our Vision Care products are among the world's most trusted.

Our research, grant and training programs help advance eye care around the world.

Total eye care market:

$35b (2024)

REFRACTIVE ERRORS

(157 million with moderate-to-severe uncorrected refractive errors1)

PRESBYOPIA

(1.8 billion sufferers2)

DRY EYE

(1.6 billion sufferers3)

CATARACTS

(65 million with moderate-to-severe vision impairment from cataracts2)

DIABETIC RETINOPATHY

(146 million sufferers2)

GLAUCOMA

(131 million sufferers4)

1. Source: Resnikoff S, Pascolini D, Mariotti SP, Pokharel GP. Global magnitude of visual impairment caused by uncorrected refractive errors in 2004. Bull World Health Organ. 2008 Jan;86(1):63-70. 2. Source: World Health Organization. World Report on Vision. 2019. 3. Source: Market

Scope: 2020 Dry Eye Products Market Report. 4. Source: Market Scope: 2021 Glaucoma Surgical Device Market Report. 4



Alcon strategy


Attract, develop and retain experts in eye care customers and technology

We focus on eye care We create value by applying specialty market knowledge and specialty technical knowledge to create products that improve sight

Reinvest in R&D and product development

Leverage expertise to invent or acquire innovative products

Commercialize globally and create a superior customer experience

Create data that demonstrate

value and drive access

5

Innovating in Ophthalmic Surgery


Global cataract procedure volumes grow largely in line with population...

Global cataract surgery volume, 2015-2025

Units, billions

25.0

  • Cataract procedure volumes have

22.2 23.5 24.2 25.5

20.4

27.2

27.8 29.2 30.4 30.9

Long-term market growth

grown steadily (4-5%) in line with the aging population, reflecting stable

2021

2020

2015 2016 2017 2018 2019 2022 2023 2024 2025

COVID-19 impact

YOY

growth,

%

+5.6% +3.2% +5.2% +6.7%

+4.8% +4.0%

+~2%

+4-5%

demand

  • YoY procedure

    Global population for 65+, 2014-2024,

    People, billions

    +3.3%

    growth is typically within ±2% of population

    0.6

    2015

    0.6

    2016

    0.7

    2017

    0.7

    2018

    0.7

    2019

    0.7

    2020

    0.8

    2021

    0.8

    2022

    0.8

    2023

    0.8

    2024

    0.9

    2025

    growth

    Source: MarketScope; UN population data (OurWorldinData - 65+ population); Cataract volume based on foldable IOLs, 2025 is estimated 7

    Significant Surgical product flow

    2022-2025

    2026-2027







    NEXT-GEN PHACO

    (Unity CS launched Q4-25)







    NEXT-GEN DIAGNOSTIC





    NEXT-GEN MICROSCOPE



    NEXT-GEN CLAREON MONO + & TORIC +





    NEXT-GEN CLAREON VIVITY



    Dry AMD

    NEXT-GEN CATARACT PLANNER

    Note: List is not exhaustive. New product launches may not be listed in chronological order. See Safe Harbor statement and the assumptions underlying our outlook for more information. 8

    Surgical ecosystem: full portfolio offering by 2027

    Suite of best-in-class devices that span across clinic, cloud and operating room, working in concert



    Clinic

    Cloud

    Operating Room (OR)

    Surgical Planner

    Clinical decision support and remote planning for cataract surgery

    • Transmit surgical plan to OR

      Unity M

      w/ Unity GPS, digital oculars, WAVS

      • Pre-op: check available inventory

      • Post-op: archival of surgical data

      • Perform the surgery

        Diagnostics

        Unity DX

  • In-clinic: take measurement data

  • Cloud: remote planning

  • CE Mark and FDA clearance gained; user studies and manufacturing ramp-up ongoing

  • Pilot launch late 20261, global rollout in mid-2027

    Inventory Manager

    Real-time inventory ordering, consignment management & analytics

  • Record inventory used

  • Transmit surgical data

Unity VCS/CS

with consumables

1. Pilot launch OUS in Q4 2026

Note: WAVS = wide angle viewing system, digi bino = digital binoculars (digital image in a familiar analog ocular format); Unity GPS = image guidance 9

Unity VCS & CS













Large installed base for strong replacement pipeline

~3k average Unity VCS & CS placements, driving equipment revenue

  • ~10-year replacement cycle, from date of acquisition

  • 20252: launched Unity VCS first, to…

    • Address older installed base and more complicated surgeries

    • Deliberately managing pace of installations

  • 2026: launching Unity CS

  • Targeting ASP uplift on dedicated consumables



>30k Centurion & Constellation installed base

30K+ units placed worldwide1 (#1)









  1. Alcon data on file

  2. 2025 launches are first market launches, other key market launches will occur across 2025-2026+ based on regulatory timing 10

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