Acurx Pharmaceuticals Announces Scientific Poster Presentation of Ibezapolstat's Microbiome Preservation Data in Multiply-recurrent C. difficile Infection

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STATEN ISLAND, N.Y., July 14, 2026 /PRNewswire/ -- Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) a clinical stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial infections, announced today that a poster presentation entitled: Microbiome Restoration Potential of Ibezapolstat vs. Comparator Antibiotics in Patients with Multiply-recurrent Clostridioides difficile Infection (CDI) was presented by Kevin Garey, PharmD, MS, FIDSA, Professor and Chair, University of Houston College of Pharmacy, Principal Investigator for microbiology and microbiome aspects of the IBZ clinical trial program at the 18th Biennial Congress of the Anaerobe Society of the Americas held at Columbia University Irving Medical Center in New York City from July 8 to 10, 2026. Studies were performed at the University of Houston to determine whether beneficial gut microbes are present in patients with multiple (≥2) recurrences of Clostridioides difficile infection (rCDI). The objectives of this study were to determine whether beneficial microbes identified in the IBZ Phase 2 studies in patients with initial and 1st recurrent CDI are still present in patients with multiple (≥2) recurrent CDI and to assess killing effects of IBZ vs. comparators in planktonic (non-biofilm) and biofilm mono- and duo-culture studies; specifically, measuring killing of VRE by VAN, FDX, and IBZ in planktonic and biofilm cultures.

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