| Biomarin Pharmaceutical Inc. | 6.03M | US$345M | 8.1% |
| Neurocrine Biosciences, Inc. | 1.88M | US$317M | 7.4% |
| Abivax Sa | 2.35M | US$313M | 7.3% |
| United Therapeutics Corporation | 435K | US$236M | 5.5% |
| Enliven Therapeutics, Inc. | 4M | US$203M | 4.7% |
| Nurix Therapeutics, Inc. | 8.05M | US$195M | 4.6% |
| Bicara Therapeutics Inc. | 5.25M | US$156M | 3.6% |
| Taysha Gene Therapies, Inc. | 19.4M | US$132M | 3.1% |
| Arrowhead Pharmaceuticals, Inc. | 1.57M | US$128M | 3.0% |
| Abbott Laboratories | 1.4M | US$127M | 3.0% |
| Zimmer Biomet Holdings, Inc. | 1.4M | US$121M | 2.8% |
| Disc Medicine, Inc. | 1.55M | US$113M | 2.6% |
| Monte Rosa Therapeutics, Inc. | 4.6M | US$111M | 2.6% |
| Insulet Corporation | 670K | US$102M | 2.4% |
| Sanofi Sa | 2M | US$85.3M | 2.0% |
| Revolution Medicines, Inc. | 450K | US$84.3M | 2.0% |
| Biocryst Pharmaceuticals, Inc. | 8.3M | US$83M | 1.9% |
| Dyne Therapeutics, Inc. | 3.38M | US$75M | 1.8% |
| Nektar Therapeutics | 1M | US$69.8M | 1.6% |
| Globus Medical, Inc. | 850K | US$67.2M | 1.6% |
| Tarsus Pharmaceuticals, Inc. | 1.05M | US$66.1M | 1.5% |
| Trevi Therapeutics, Inc. | 3.1M | US$57.8M | 1.4% |
| Repligen Corporation | 400K | US$54.6M | 1.3% |
| Bristol-myers Squibb Company | 800K | US$46.1M | 1.1% |
| Xenon Pharmaceuticals Inc. | 700K | US$42.3M | 0.99% |
| Bright Minds Biosciences Inc. | 545K | US$38.3M | 0.89% |
| Madrigal Pharmaceuticals, Inc. | 65,000 | US$34.9M | 0.82% |
| Myriad Genetics, Inc. | 5.74M | US$32.7M | 0.77% |
| Rapport Therapeutics, Inc. | 730K | US$30.4M | 0.71% |
| Crescent Biopharma, Inc. | 1.63M | US$29.3M | 0.69% |
| Ge Healthcare Technologies Inc. | 450K | US$28.8M | 0.67% |
| Insmed Incorporated | 250K | US$26.7M | 0.62% |
| Viking Therapeutics, Inc. | 680K | US$26.5M | 0.62% |
| Beta Bionics, Inc. | 1.6M | US$25.1M | 0.59% |
| Regeneron Pharmaceuticals, Inc. | 40,000 | US$24.9M | 0.58% |
| Solid Biosciences Inc. | 2.16M | US$21.6M | 0.50% |
| Alto Neuroscience, Inc. | 785K | US$20.7M | 0.48% |
| First Tracks Biotherapeutics, Inc. | 1.01M | US$20.4M | 0.48% |
| Lexeo Therapeutics, Inc. | 4.32M | US$20.1M | 0.47% |
| Savara, Inc. | 2.72M | US$16.8M | 0.39% |
| Damora Therapeutics, Inc. | 575K | US$15M | 0.35% |
| Spyglass Pharma, Inc. | 670K | US$14.9M | 0.35% |
| Tectonic Therapeutic, Inc. | 425K | US$14.6M | 0.34% |
| Avalo Therapeutics, Inc. | 775K | US$14.3M | 0.33% |
| Evommune, Inc. | 1M | US$13.3M | 0.31% |
| Kailera Therapeutics, Inc. | 575K | US$12.7M | 0.30% |
| Anteris Technologies Global Corp. | 1.01M | US$9.95M | 0.23% |
| Zenas Biopharma, Inc. | 365K | US$9.26M | 0.22% |
| Voyager Therapeutics, Inc. | 2.63M | US$9.19M | 0.21% |
| Onkure Therapeutics, Inc. | 1.83M | US$8.33M | 0.19% |
| Surrozen, Inc. | 305K | US$7.91M | 0.18% |
| Monopar Therapeutics Inc. | 75,727 | US$7.01M | 0.16% |
| Zura Bio Limited | 1.17M | US$6.93M | 0.16% |
| Olema Pharmaceuticals, Inc. | 419K | US$5.24M | 0.12% |
| Palisade Bio, Inc. | 2.5M | US$5.22M | 0.12% |
| Ibio, Inc. | 2.6M | US$4.55M | 0.11% |
| Sagimet Biosciences Inc. - Series A | 535K | US$4.14M | 0.10% |
| Rezolute, Inc. | 383K | US$1.99M | 0.05% |
| Tenax Therapeutics, Inc. | 53,439 | US$778K | 0.02% |
| Aprea Therapeutics, Inc. | 350K | US$281K | <0.01% |
| Inspire Medical Systems, Inc. | 0 | US$0 | 0.00% |
| Kalvista Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Macrogenics, Inc. | 0 | US$0 | 0.00% |
| Maplight Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Nuvalent, Inc. | 0 | US$0 | 0.00% |
| Passage Bio, Inc. | 0 | US$0 | 0.00% |
| Protagonist Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Regenxbio Inc. | 0 | US$0 | 0.00% |
| Scholar Rock Holding Corporation | 0 | US$0 | 0.00% |
| Soleno Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Terns Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Tyra Biosciences, Inc. | 0 | US$0 | 0.00% |
| Vera Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Veracyte, Inc. | 0 | US$0 | 0.00% |
| Waters Corporation | 0 | US$0 | 0.00% |
| West Pharmaceutical Services, Inc. | 0 | US$0 | 0.00% |
| Absci Corporation | 0 | US$0 | 0.00% |
| Agios Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Apogee Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Arvinas, Inc. | 0 | US$0 | 0.00% |
| Ascendis Pharma A/s | 0 | US$0 | 0.00% |
| Boston Scientific Corporation | 0 | US$0 | 0.00% |
| Candel Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Celldex Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Cogent Biosciences, Inc. | 0 | US$0 | 0.00% |
| Cytokinetics, Incorporated | 0 | US$0 | 0.00% |
| Denali Therapeutics Inc. | 0 | US$0 | 0.00% |
| Engene Holdings Inc. | 0 | US$0 | 0.00% |
| Fulcrum Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Genedx Holdings Corp. | 0 | US$0 | 0.00% |
| Geron Corporation | 0 | US$0 | 0.00% |