| Krystal Biotech, Inc. | 939K | US$349M | 12.0% |
| Celcuity Inc. | 1.7M | US$178M | 6.1% |
| Tg Therapeutics, Inc. | 2.93M | US$161M | 5.5% |
| Insulet Corporation | 1.05M | US$160M | 5.5% |
| United Therapeutics Corporation | 226K | US$122M | 4.2% |
| Inspire Medical Systems, Inc. | 1.93M | US$86.2M | 3.0% |
| Rigel Pharmaceuticals, Inc. | 1.84M | US$72.1M | 2.5% |
| Ani Pharmaceuticals, Inc. | 868K | US$71.8M | 2.5% |
| Beta Bionics, Inc. | 4.39M | US$68.8M | 2.4% |
| Vericel Corporation | 1.46M | US$64.9M | 2.2% |
| Praxis Precision Medicines, Inc. | 178K | US$59.4M | 2.0% |
| Geron Corporation | 42.8M | US$54.8M | 1.9% |
| Erasca, Inc. | 2.7M | US$49.5M | 1.7% |
| Neuropace, Inc. | 2.91M | US$46.3M | 1.6% |
| Progyny, Inc. | 1.6M | US$46.2M | 1.6% |
| Indivior Pharmaceuticals, Inc. | 1.06M | US$43.7M | 1.5% |
| Parabilis Medicines, Inc. | 1.47M | US$40.1M | 1.4% |
| Globus Medical, Inc. | 469K | US$37M | 1.3% |
| Arcus Biosciences, Inc. | 1.17M | US$36M | 1.2% |
| Syndax Pharmaceuticals, Inc. | 1.63M | US$35.6M | 1.2% |
| Nurix Therapeutics, Inc. | 1.47M | US$35.5M | 1.2% |
| Jade Biosciences, Inc. | 1.55M | US$34.5M | 1.2% |
| Unitedhealth Group Incorporated | 80,000 | US$33.3M | 1.1% |
| Avalo Therapeutics, Inc. | 1.65M | US$30.6M | 1.1% |
| Mbx Biosciences, Inc. | 515K | US$28.4M | 0.98% |
| Palisade Bio, Inc. | 13.1M | US$27.3M | 0.94% |
| Organogenesis Holdings Inc. | 10.1M | US$24.6M | 0.85% |
| Supernus Pharmaceuticals, Inc. | 520K | US$24.2M | 0.83% |
| Procept Biorobotics Corporation | 1M | US$22.6M | 0.78% |
| Tango Therapeutics, Inc. | 709K | US$22.2M | 0.76% |
| Inhibikase Therapeutics, Inc. | 10.9M | US$22.1M | 0.76% |
| Trevi Therapeutics, Inc. | 1.18M | US$22M | 0.76% |
| Biomarin Pharmaceutical Inc. | 376K | US$21.5M | 0.74% |
| Argenx Se | 19,955 | US$18.5M | 0.64% |
| Nuvectis Pharma, Inc. | 1M | US$18.4M | 0.63% |
| Capricor Therapeutics, Inc. | 762K | US$18.3M | 0.63% |
| Edgewise Therapeutics, Inc. | 451K | US$18.3M | 0.63% |
| Prelude Therapeutics Incorporated | 3.38M | US$18M | 0.62% |
| Xenon Pharmaceuticals Inc. | 267K | US$16.1M | 0.56% |
| C4 Therapeutics, Inc. | 3.38M | US$15.8M | 0.54% |
| Orthopediatrics Corp. | 732K | US$14M | 0.48% |
| Avalyn Pharma Inc. | 419K | US$13.8M | 0.48% |
| Biodesix, Inc. | 586K | US$13.2M | 0.46% |
| Spyre Therapeutics, Inc. | 147K | US$13.1M | 0.45% |
| Twist Bioscience Corporation | 105K | US$10.8M | 0.37% |
| Vir Biotechnology, Inc. | 1M | US$10.2M | 0.35% |
| Alnylam Pharmaceuticals, Inc. | 33,050 | US$9.95M | 0.34% |
| Immunovant, Inc. | 252K | US$9.71M | 0.33% |
| Insmed Incorporated | 90,250 | US$9.62M | 0.33% |
| Septerna, Inc. | 275K | US$9.21M | 0.32% |
| Nektar Therapeutics | 128K | US$8.96M | 0.31% |
| Mirum Pharmaceuticals, Inc. | 75,000 | US$8.78M | 0.30% |
| Artivion, Inc. | 388K | US$8.72M | 0.30% |
| Tandem Diabetes Care, Inc. | 575K | US$8.68M | 0.30% |
| Enliven Therapeutics, Inc. | 166K | US$8.41M | 0.29% |
| Sionna Therapeutics, Inc. | 178K | US$7.82M | 0.27% |
| Cerus Corporation | 2.5M | US$7.3M | 0.25% |
| Immunic, Inc. | 450K | US$6.92M | 0.24% |
| Invivyd, Inc. | 7.71M | US$6.73M | 0.23% |
| Merck & Company, Inc. | 50,000 | US$6.42M | 0.22% |
| Relmada Therapeutics, Inc. | 842K | US$5.83M | 0.20% |
| Evolus, Inc. Common Stock | 822K | US$5.71M | 0.20% |
| Zentalis Pharmaceuticals, Inc. | 950K | US$4.61M | 0.16% |
| Karyopharm Therapeutics Inc. | 440K | US$4.3M | 0.15% |
| Context Therapeutics Inc. | 7.06M | US$3.91M | 0.13% |
| Pulmonx Corporation | 2.79M | US$3.62M | 0.12% |
| Sab Biotherapeutics, Inc. | 900K | US$3.51M | 0.12% |
| Tectonic Therapeutic, Inc. | 102K | US$3.5M | 0.12% |
| Axogen, Inc. | 57,036 | US$2.63M | 0.09% |
| Satellos Bioscience Inc | 314K | US$2.44M | 0.08% |
| Arrivent Biopharma, Inc. | 50,000 | US$1.74M | 0.06% |
| Corcept Therapeutics Incorporated | 19,653 | US$1.71M | 0.06% |
| Solid Biosciences Inc. | 150K | US$1.5M | 0.05% |
| Veracyte, Inc. | 25,000 | US$1.47M | 0.05% |
| Cullinan Therapeutics, Inc. | 50,000 | US$911K | 0.03% |
| Inspiremd Inc. | 1.05M | US$732K | 0.03% |
| Genedx Holdings Corp. | 10,000 | US$687K | 0.02% |
| Iovance Biotherapeutics, Inc. | 150K | US$624K | 0.02% |
| Larimar Therapeutics, Inc. | 188K | US$574K | 0.02% |
| Cg Oncology, Inc. | 5,000 | US$355K | 0.01% |
| Equillium, Inc. | 90,000 | US$288K | <0.01% |
| Natera, Inc. | 1,000 | US$271K | <0.01% |
| Neogenomics, Inc. | 10,000 | US$146K | <0.01% |
| Jasper Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Lb Pharmaceuticals Inc | 0 | US$0 | 0.00% |
| Oruka Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Rapport Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Staar Surgical Company | 0 | US$0 | 0.00% |
| Travere Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Tyra Biosciences, Inc. | 0 | US$0 | 0.00% |
| Vaxcyte, Inc. | 0 | US$0 | 0.00% |
| Zymeworks Inc. | 0 | US$0 | 0.00% |
| Anaptysbio, Inc. | 0 | US$0 | 0.00% |
| Arrowhead Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Cogent Biosciences, Inc. | 0 | US$0 | 0.00% |
| Cytomx Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Dexcom, Inc. | 0 | US$0 | 0.00% |
| Eton Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Inhibrx Biosciences, Inc. | 0 | US$0 | 0.00% |