Treace Medical Concepts, Inc. · NASDAQ:TMCI
Treace Medical Concepts — Technical Presentation (September 2026)
20 slides from Treace Medical Concepts's technical presentation, September 2026
Slide 1: Five-Year Analysis of Triplanar Tarsometatarsal Arthrodesis With Early Weightbearing
Five-Year Analysis of a Prospective Multicenter Study of Triplanar Tarsometatarsal Arthrodesis With Early Weightbearing: Radiographic, Clinical, and Patient Reported Outcomes Daniel C. Farber, MD Lehigh Valley Orthopedic Institute
Slide 2: Authors and Disclosures
Authors D Farber, MD1; D Wukich, MD2, R Santrock, MD3; A Raissi, MD4; A Chhabra, MD2; J Koay, MD5; P Dayton, DPM6; M Dayton, DPM6; JP McAleer, DPM7; R Taylor, DPM8; D Hatch, DPM9 1 Lehigh Valley Orthopedic Institute, Bethlehem, PA 2 University of Texas Southwestern Medical Center, Dallas, TX 3 Duke
Slide 3: Introduction
Introduction Final results from a 5-year prospective multicenter study to evaluate the use of an instrumented system for triplanar 1st TMT correction of HV deformities: • Reproducibility of correction • Outcomes of early weightbearing • Long-term maintenance of correction • Patient-reported outcomes
Slide 4: Study Methods
Study Methods ALIGN3D prospective multicenter study (7 sites and 13 surgeons): 5-year follow-up Inclusion Exclusion Outcomes evaluated 14-58 years of age Prior HV surgery Radiographic recurrence BMI > 40 kg/m2 Return to weightbearing and activities HbA1c ≥7 Visual Analog Scale (VAS) Symptomati
Slide 5: Demographics and Baseline Characteristics
Results: Demographics and Baseline Characteristics • 137/173 (79.2%) patients completed the 60 month follow up visit.
Slide 6: Weightbearing
Results: Weightbearing ▪ Return to early, protected weightbearing within an average of 8.4 days (SD=7.43). ▪ Return to weightbearing in a shoe within an average of 6.6 weeks (SD=1.57). ▪ Return to full, unrestricted activities within an average of 4.0 months (SD=1.15).
Slide 7: Example Radiographic Results
Example Radiographic Results Baseline 6 Week 4 Month 6 Month 12 Month 24 Month 36 Month 48 Month 60 Month
Slide 8: Radiographic Measures
Results: Radiographic Measures • Significant improvements (p<0.05) of all radiographic measures were maintained over all the time points. Radiographic Measures, Mean (95% CI) Visit Baseline 6 Week 24 month 36 month 48 month 60 month (N=173) (N=171) (N=b) (N=c) (N=d) (N=e) 25.9° 8.9° 7.8° 7.1° 6.8° 6
Slide 9: Radiographic Recurrence
Results: Radiographic Recurrence • Recurrence was defined using two thresholds: Post-op HVA >20° or HVA >15°. Visit Recurrence Definition Rate (95% CI of the proportion) HVA >20° HVA >15° 60 Month 0.8% (1/133) 5.3% (7/133) (0.02, 4.12) (2.14, 10.54)
Slide 10: Tibial Sesamoid Position
Tibial Sesamoid Position • Hardy and Clapham (JBJS 1951) • Tibial Sesamoid Position (TSP) as a marker of axial rotation correction • Does axial rotation of the first ray have an impact on long-term results after HV surgery?
Slide 11: Radiographic Predictors of Recurrence
Results: Radiographic Predictors of Recurrence • A statistically significant association was found between recurrence and the following variables: • 6-week TSP position (OR = 0.5, p = 0.0041) • 6-week HVA (OR = 1.4, p = 0.0007) • The odds of recurrence was 95% lower in patients with a 6-week TSP ≤ 3
Slide 12: Patient-Reported Outcomes
Results: Patient-Reported Outcomes • Significant improvements (p<0.05) from baseline in VAS and all MOxFQ domains at all post-operative timepoints. VAS Score, Mean (95% CI) Baseline Week 6 Month 6 Month 12 Month 24 (N=173) (N=171) (N=160) (N=148) (N=156) 4.7 1.8 1.4 1.1 0.9 (4.4, 5.0) (1.5, 2.0) (1.
Slide 13: Patient-Reported Outcomes
Results: Patient-Reported Outcomes • Significant improvements (p<0.05) across all PROMIS domains at all post-operative timepoints except Depression which exhibited sustained improvement starting at 48 months. PROMIS Score by Domain, Mean (95%, CI) Domain Baseline 6 Month 24 Month 48 Month 60 Month (
Slide 14: Patient-Reported Outcomes
Results: Patient-Reported Outcomes • Patients with recurrence were not significantly different in terms of patient reported outcomes • Both PROMIS and MOxFQ demonstrated an overall improvement in domain scores in both the Non-Recurrence and Recurrence groups post- operatively. Representative x-rays
Slide 15: Complications
Complications ▪ 15 (8.7%) of the 173 patients required non-elective reoperation due to the situations listed below; 4 (2.3%) patients requested hardware removal without medical indication or complication. ▪ 12 (6.9%) patients experienced at least one clinical complication not requiring surgical inte
Slide 16: Discussion
Discussion ▪ Overall favorable results of first TMT arthrodesis with an early return to protected weightbearing, excellent anatomic correction, high union rates, and improvement in patient-reported outcomes. ▪ LaLevee (FAI 2023) recent systematic review of distal osteotomy with 5+ years follow-up fo
Slide 17: Limitations
Limitations • Single arm study without a control or comparison group. • Hallux valgus deformities were selected per these parameters: HVA between 16°- 40° and IMA between 10°- 22°. • Hypermobility was not a study parameter. • Study sites included surgeons who were considered experienced users of the
Slide 18: Conclusions
Conclusions • Early protected weightbearing within 8.4 days on average. • Significant improvements in radiographic correction (HVA, IMA, TSP, Sagittal IMA) at 6 weeks and maintained through 60 months. • Low radiographic recurrence at 60 months (using HVA thresholds of 20° and 15°, respectively). • A
Slide 19: Acknowledgments
Acknowledgments Thank you to the participating Principal Investigators and study sites. • Jefferson City Medical Group, Jefferson • Foot and Ankle Center of the Rockies, City, MO Greeley, CO • Jody P. McAleer, DPM, FACFAS • Daniel J. Hatch, DPM, FACFAS • William J. Duke, DPM, FACFAS • Stonebriar Foo
Slide 20: References
References 1. LaLevee M, de Cesar Netto C, ReSurg, Boublil D, Coillard J-Y: Recurrence Rates With Longer-Term Follow- up After Hallux Valgus Surgical Treatment With Distal Metatarsal Osteotomies: A Systematic Review and Meta-analysis. Foot Ankle Int 2023;44:210-22.10711007231152487. 2. HARDY RH, CLA
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