Treace Medical Concepts, Inc. · NASDAQ:TMCI

Treace Medical Concepts — Technical Presentation (September 2025)

21 slides from Treace Medical Concepts's technical presentation, September 2025

  1. Slide 1: Prospective Multicenter Study of Instrumented Mini-Open Triplanar TMT Arthrodesis

    Prospective Multicenter Study Assessing Radiographic and Patient Outcomes Following an Instrumented Mini-Open Triplanar Tarsometatarsal Arthrodesis with Early Weightbearing Jody McAleer, DPM, FACFAS Jefferson City Medical Group

  2. Slide 2: Disclosures

    Disclosures Authors JP McAleer, DPM1; R Santrock, MD2; A Chhabra, MD3; JE McAlister, DPM4; R Taylor, DPM5; D Farber, MD6; A Raissi, MD7; P Steinke, DPM8; M Allen, DPM9; A Shane, DPM10; D Kile, MS11; J Daigre, MD12 1 Jefferson City Medical Group, Jefferson City, MO 2 Duke University, Durham NC 3 Univ

  3. Slide 3: Introduction

    Introduction Results from a 2-year prospective multicenter study to evaluate the use of an instrumented system for triplanar 1st TMT correction of HV deformities through a mini-open incision:  Reproducibility of correction.  Outcomes of early weightbearing.  Maintenance of correction.  Patient-r

  4. Slide 4: Study Methods

    Study Methods Mini3D prospective multicenter study (9 sites and 9 surgeons): 2-year follow-up Inclusion criteria:  14-58 years of age  Symptomatic HV (IMA between 10.0 - 22.0°; HVA between 16.0 - 40.0°) Exclusion criteria:  Prior HV surgery  Metatarsus adductus angle (MAA) ≥23°  BMI >40 kg/m2 

  5. Slide 5: Surgical Methods

    Surgical Methods Mini-Open 1st TMT Arthrodesis:  Patients treated with an instrumented 1st TMT procedure through a mini-open (<4cm) dorsal incision.  Instrument-assisted triplanar deformity correction with a cut guide for TMT joint cuts.  Biplanar locking construct with protected early weightbear

  6. Slide 6: Demographics and Baseline Characteristics

    Results: Demographics and Baseline Characteristics  75/105 patients completed their 12-month follow up visit and 11 patients completed their 24-month follow up.  Early protected weightbearing in an average of 7.9 days (SD=6.0). Baseline Characteristics Category Patient Population Age (years), mean

  7. Slide 7: Radiographic Measures

    Results: Radiographic Measures  Significant (p<0.01) improvements over baseline in radiographic measures (HVA, IMA, TSP, osseous foot width) at all post-op time points through 12 months. Continued improvement observed in the n=11 patients with 24-month data.  94.2% (98/104) of patients achieved 6-

  8. Slide 8: Radiographic Recurrence

    Results: Radiographic Recurrence  Recurrence was assessed using two thresholds from literature: HVA >15° or HVA >20°.  None of the patients had recurrence using post-op HVA of >20° at 12 or 24 months. Recurrence Definition Rate (95% CI of the proportion) Visit HVA >15 HVA >20 12 Month 5.5% (4/73

  9. Slide 9: Circumferential Measurements

    Results: Circumferential Measurements Circumferential Measurements in cm, Mean (95% Confidence Interval) Swelling Baseline (n=105*) 6 Week (n=104) 6 Month (n=98) 12 Month (n=75) Measures Forefoot 20.7 20.8 20.2 19.8 Circumference (20.1, 21.3) (20.2, 21.5) (19.5, 20.8) (19.1, 20.5) Midfoot 20.2 20.9

  10. Slide 10: Scar Analysis

    Results: Scar Analysis  Representative preoperative (left) and 24-month postoperative (right) incision/scar assessments Baseline 6 Week 6 Month 12 Month 24 Month 10

  11. Slide 11: Scar Analysis

    Results: Scar Analysis  Representative preoperative (left) and 12-month postoperative (right) incision/scar assessments Baseline 6 Week 4 Month 6 Month 12 Month 11

  12. Slide 12: POSAS: Patient and Observer Assessment Scale

    POSAS: Patient and Observer Assessment Scale Survey question examples POSAS is part of the Dutch Burns Foundation copyright © p.p.m. van zuijlen, beverwijk-nl Zeestraat 29 | 1941 AJ Beverwijk | The Netherlands For more information or for a free license, e-mail: info@posas.nl 12

  13. Slide 13: Incision Length and Scar Analysis

    Results: Incision Length and Scar Analysis  High patient satisfaction with post-operative scar appearance. Incision Length (cm) Median (Min, Max) 3.5 (3.0, 4.0) POSAS* (Mean 95% Confidence Interval) 4 Month 6 Month 12 Month 24 Month (n=98) (n=98) (n=75) (n=11) Observer 14.6 12.1 10.8 7.5 (13.4, 15.

  14. Slide 14: Patient Reported Outcomes

    Results: Patient Reported Outcomes  Significant improvement over baseline in VAS and MOxFQ through 12m post-op.  Continued improvement observed in the n=11 patients with 24-month data. VAS Mean (95% Confidence Interval) Measure Baseline 6 Week 6 Month 12 Month 24 Month (n=105) (n=104) (n=98) (n=74

  15. Slide 15: Patient Reported Outcomes

    Results: Patient Reported Outcomes  Significant improvements were observed across all PROMIS domains at 6 and 12 months post-operatively.  Continued improvements were also observed in the n=10 24-month subjects. PROMIS Domain Baseline 6 Month 12 Month 24 Month (n=99) (n=92) (n=70) (n=10) Ability t

  16. Slide 16: Metatarsalgia

    Results: Metatarsalgia  Majority of patients experienced resolution of pre-op metatarsalgia. Metatarsalgia Metatarsalgia No Metatarsalgia Metatarsalgia at 12 months at 12 months Row Total at baseline n (row %) (column %) n (row %) (column %) Yes 0 28 (100.0%) (38.4%) 28 No 2 (4.3%) (100.0%) 45 (95.

  17. Slide 17: Complications

    Complications  1 (1.0%) of the 105 patients required reoperation (hardware removal).  11 (10.5%) patients experienced at least one clinical complication not requiring surgical intervention.  Symptoms of 3 patients were ongoing at the time of data analysis; symptoms were pain (N=2) and malunion/st

  18. Slide 18: Discussion

    Discussion • Overall favorable results with triplanar 1st TMT correction of HV deformities through a mini- incision (median incision length: 3.5cm) with an early return to weightbearing, low recurrence rates, and improvement in patient-reported outcomes at 12 months. • LaLevee (FAI 2023) recent syst

  19. Slide 19: Conclusion

    Conclusion Favorable clinical and patient-reported outcomes with mini-open approach (median incision length: 3.5cm) 12 months post-procedure: • Early protected weightbearing in average of 7.9 days. • Significant improvements in radiographic correction (HVA, IMA, TSP, osseous foot width) at 6 weeks a

  20. Slide 20: Acknowledgements

    Acknowledgements Thank you to the participating Principal Investigators and study sites.  Jefferson City Medical Group, Jefferson City, MO  DOC Orthopaedics – Decatur and Hartselle, AL  Jody P. McAleer, DPM, FACFAS  Justin Daigre, MD  Stonebriar Foot & Ankle, Frisco, TX  Sports Medicine Associ

  21. Slide 21: References

    References 1. LaLevee M, de Cesar Netto C, ReSurg, Boublil D, Coillard J-Y: Recurrence Rates With Longer- Term Follow-up After Hallux Valgus Surgical Treatment With Distal Metatarsal Osteotomies: A Systematic Review and Meta-analysis. Foot Ankle Int 2023;44:210-22.10711007231152487. 21 M3495C

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