PetVivo Holdings Inc · OTC:PETV

PetVivo — Investor Presentation (March 2026)

34 slides from PetVivo's investor presentation, March 2026

  1. Slide 1: Investor Presentation

    Investor Presentation March 2026 PETV (OTCQX)

  2. Slide 2: Forward-Looking Statements

    Forward-Looking Statements This presentation and the accompanying oral commentary contains forward-looking statements within the meaning of the federal securities laws, which statements are subject to substantial risks and uncertainties that could cause actual results to differ materially from those

  3. Slide 3: PetVivo - Subsidiaries Org Chart

    PetVivo - Subsidiaries Org Chart PetVivo Holdings, Inc. (PETV) Human Subsidiary Gel-Del Technologies, Inc. PetVivo AI, Inc. PetVivo Animal Health. Inc. Veterinary AI Product Sales (Name TBD) Manufacturer of All Human and Sales Entity for all Vet Products Human Product R&D and Sales Vet Products Enti

  4. Slide 4: Company Highlights

    Company Highlights Market Opportunity Growth Drivers +$39.8B US companion animal veterinary care and product sales market with ~ 6% Innovation historical CAGR (2020-2024)* Strategic Partnerships with experts in functional materials for innovation and product expansion of regenerative product portfol

  5. Slide 5: Osteoarthritis (OA) Opportunity

    Osteoarthritis (OA) Opportunity $39.8B Veterinary Care and Product Sales Market Osteoarthritis: Current solutions treat a common affliction symptoms, but do not of the joints manage the cause • Affects approximately 34 million • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) adult dogs and 1 million

  6. Slide 6: Viscosupplementation

    Viscosupplementation A strong hydrated biomaterial that facilitates enhanced lubrication and joint-cushioning properties. Micro-scaffolds Over time, micro-scaffolds adhere to and integrate with the existing synovial membrane. Collagen-Elastin Microparticles Porous, spongy particles absorb and releas

  7. Slide 7: An Optimal OA Solution: Spryng with OsteoCushion Technology

    An Optimal OA Solution: Spryng® with OsteoCushion® Technology ● Spryng provides a biocompatible lubricious and viscoelastic biomaterial, which promotes the restoration of joint mechanics to improve joint function ○ Similar components/function found in natural cartilage (i.e. collagen, elastin and he

  8. Slide 8: Spryng with OsteoCushion Technology

    Spryng® with OsteoCushion® Technology ● Spryng is a unique new medical device addressing the root cause of the affliction, not just the symptoms ● Purified natural components self-assemble to form an insoluble, hydrated matrix ● Protein source bovine tissues (i.e. medical grade collagen and elastin)

  9. Slide 9: Spryng Mechanism of Action

    Spryng® Mechanism of Action ● An animal suffering from osteoarthritis generally exhibits damaged and/or lost cartilage thereby creating bone on bone contact that results in an increase of joint inflammation, pain, and further loss of cartilage ● Spryng reinforces synovial membrane function, without

  10. Slide 10: Spryng Canine Success: Cooper

    Spryng® Canine Success: Cooper Condition Treatment Results¹ ● 7-year-old mixed-breed ● Immediately after ● On January 14, 2025, dog. injections a clear Cooper received Spryng® with OsteoCushion® difference in Cooper’s ● Diagnosed with severe Technology injections in mobility was seen. arthritis in b

  11. Slide 11: Spryng Equine Success: Fergie

    Spryng® Equine Success: Fergie Click to View Video Online History Exam & Diagnosis Results¹ ● 16-year-old Saddlebred ● Choppy gait in her backend, ● Mild improvement after mare. intermittent left front one week. lameness ~1 year. ● Fergie shows as a ● After one month, Saddlebred monthly and ● Grade

  12. Slide 12: Spryng Competitive Distinctions

    Spryng® Competitive Distinctions ● Outcomes address affliction/not just symptoms ● Current treatments rely on biologic activity to treat symptoms; Spryng provides structural components to address affliction ● Price/Cost advantage ● Derived from all natural materials ● Ease of application ● Vet clini

  13. Slide 13: Spryng Product Category Comparison

    Spryng® Product Category Comparison *NSAIDs: Rimadyl *Orthobiologics Arthramid Features Spryng® Librela Solensia Adequan HA/Legend Synovetin Banamine PRP, APS Noltrex Injections per Year 1 12 16-18 N/A 3-4 2-3 1 Benefits Last up to x x x 12 Months or More Bioscaffold From Naturally-Derived x Compone

  14. Slide 14: Spryng Tolerance Studies

    Spryng® Tolerance Studies Canine Tolerance Feline Tolerance Purpose: Assess tolerance of Spryng® Purpose: Assess tolerance of Spryng® administration in dogs. administration in cats. Design: 20 healthy dogs received intra-articular Design: 10 healthy female cats received intra- injection with saline

  15. Slide 15: Spryng Clinical Studies

    Spryng® Clinical Studies Six Clinical Trials Conducted To Date — All With Positive, Confirming Results Canine Hip OA Canine Stifle OA/CCL Disease Purpose: Study the effects of Collagen-Elastin Purpose: Evaluate benefit and tolerability of an intra- Hydrogel Microparticles (Spryng) on pain & function

  16. Slide 16: New Spryng Clinical Trials

    New Spryng® Clinical Trials Additional Studies 2025 - 2026 Underway or Recently Completed, Awaiting Publication Canine Study at Colorado Canine Study Canine Study State University Principal investigators: Principal investigators: Principal investigators: Felix ● Jamie Gaynor DVM, MS, ● Sherman Canap

  17. Slide 17: No Centrifuge Required

    No Centrifuge Required Freeze-dried, pooled, leukoreduced, RBC removed, allogeneic. No Blood Draw Sterility, endotoxin and mycoplasma evaluated every time. Consistent Dosing Platelet Derived Growth Factor (PDGF-BB) measured in every batch. Total platelet dose per vial equals 4 billion platelets. Con

  18. Slide 18: What is Platelet-Rich Plasma (PRP)?

    What is Platelet-Rich Plasma (PRP)? ● The most common regenerative therapy utilized in veterinary medicine. ● Concentrated preparation of platelets and plasma. ● First published use in the 1970s as an intralesional and fracture repair product in horses and dogs. ● Benefits of PRP ○ Many publications

  19. Slide 19: Common Uses of Platelet-Rich Plasma in Veterinary Medicine

    Common Uses of Platelet-Rich Plasma in Veterinary Medicine In Conjunction with Stem Cell Therapy Wound Healing Post Surgical Healing Ophthalmic Uses Dental and Oral ● Corneal Ulceration ● Keratoconjunctivitis Sicca Surgical Procedures ● Descemetocele Musculoskeletal Disease/Injury ● Osteoarthritis ●

  20. Slide 20: State-of-the-Art Production Facilities

    State-of-the-Art Production Facilities ● Spryng® product is manufactured in PetVivo’s ISO certified cleanrooms (ISO 8 to ISO 7 to ISO 5 ● Initial batch sizes of approx. 500 syringes; planning to increase to batches of 5,000+ syringes per month. ● Current production facility annual capacity is approx

  21. Slide 21: Comprehensive IP Portfolio

    Comprehensive IP Portfolio ● 12 US and Foreign Issued Patents ● Broad Claim Language - “Comprising” Transitions ● 6 Detailed Proprietary Trade Secrets ● Our Patents & Trade Secrets Protect: ○ Protein & Carbohydrate Based Thermoplastics ○ Biomaterials of Many Compositions ○ Medical, Drug Delivery & C

  22. Slide 22: Market Overview

    Market Overview Sources: American Pet Products Assoc.; North American Pet Health Insurance Association, American Horse Council, LendEDU Companion Animal/Veterinarian * Agricultural and professional equine markets not included ● US Pet Spend increased from $152B in 2024 to $157B in 2025 ● Veterinary

  23. Slide 23: Animal Product Pipeline

    Animal Product Pipeline No FDA Review or Clearance Required for Commercialization of Veterinary Medical Devices FDA clearance not required Product Commercial Particle Based Devices Species Safety Pilot Efficacy No. Launch VD-01 Osteoarthritis Canine (Spryng®) Q3 2021 VD-02 Osteoarthritis Equine (Spr

  24. Slide 24: Human Product Pipeline

    Human Product Pipeline FDA Review or Clearance Required for Commercialization of Human Medical Devices FDA clearance required Product Commercial Particle Based Devices Species Safety Pilot Efficacy No. Launch HD-01 Osteoarthritis Human (Spryng®) TBD HD-02 Osteoarthritis Human (SmartSpryng ) TBD Huma

  25. Slide 25: Distribution Partners

    Distribution Partners MWI Animal Health Covetrus MWI – PetVivo Distribution Services Covetrus – PetVivo Distribution Services Agreement Terms: Agreement Terms: ● Non-exclusive distribution agreement with ● Non-exclusive distribution agreement ongoing annual renewal option until with one year term th

  26. Slide 26: Wholesale Partners

    Wholesale Partners Vedco Clipper Vedco – Wholesaler Engagement: Clipper – Wholesaler Engagement: ● Wholesaler relationship to purchase ● Non-exclusive distribution agreement product from PetVivo and sell it to with one year term that automatically national distributors for subsequent sale renews ann

  27. Slide 27: Digital Landia, LLC (Agentic Pet)

    Digital Landia, LLC (“Agentic Pet”) Artificial Intelligence Exclusive White Label License What is Agentic Pet AI? Relationship: The world's first autonomous pet care AI ecosystem that leverages cutting-edge • Exclusive white label license agreement multi-agent technology to revolutionize how between

  28. Slide 28: Digital Landia, LLC (Agentic Pet)

    Digital Landia, LLC (“Agentic Pet”) Artificial Intelligence Current Development Status Anticipated Launch Timeline and Third-Party Validation • January 2026 – Expanded B2B Beta & Readiness: : • Core multi-agent architecture completed and Expanded beta with select U.S. veterinary clinics and operatin

  29. Slide 29: PetVivo Strategic Partners

    PetVivo Strategic Partners PiezoBioMembrane, Inc. (“PBM”) and Veterinary Growth Partners (“VGP”) PBM (Functional Biomaterials) Veterinary Growth Partners (Veterinarian Association) Relationship – Master Services Agreement (Joint R&D): Relationship – Vendor Partner Agreement ● Collaboration on the re

  30. Slide 30: Management Team Introduction

    Management Team Introduction Deep Bench of Industry Veterans with Decades of Experience John Lai Garry Lowenthal John F. Dolan Bryan Monninger Josh Wilhelm CEO, President & Director CFO General Counsel VP of Sales & Distributor VP of Operations & R&D Relations Andrea Cranston Kirsty Husby, DVM, MS,

  31. Slide 31: Strong Independent Board of Directors and Advisors

    Strong Independent Board of Directors and Advisors Advisors ▪ Dr. Tracy Turner, DVM, MS, Robert Costantino Joseph Jasper Robert Rudelius Diane Levitan Dipl. ACVS, Dipl. ACSMR, Director Director Director Director Amer. Academy Thermology, AAEP Board Noble Ventures Associate Professor Long Island ▪ Dr

  32. Slide 32: Growth Drivers

    Growth Drivers Sales Growth & Expansion Regen Med Portfolio Expansion & Innovation ● US Direct Veterinary Sales Force ● PrecisePRP Canine (2/2025) PrecisePRP Equine ● 100% US veterinary market coverage via (11/2025) established distributor network. ● New Product Innovation with PiezoBioMembrane ● In

  33. Slide 33: Company Highlights

    Company Highlights Market Opportunity Growth Drivers +$39.8B US companion animal veterinary care and product sales market with ~ 6% Innovation historical CAGR (2020-2024)* Strategic Partnerships with experts in functional materials for innovation and product expansion of regenerative product portfol

  34. Slide 34: John Lai

    John Lai Chief Executive Officer jlai@petvivo.com (952) 405-6216 Spryng® with OsteoCushion Technology and PrecisePRP are exclusively sold and distributed by PetVivo Animal Health. Veterinary Use Only - Federal law restricts this device to use by or on the order of a licensed veterinarian. 844-Pet-Vi

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