PetVivo Holdings Inc · OTC:PETV

PetVivo — Investor Presentation (August 2026)

36 slides from PetVivo's investor presentation, Aug 20, 2026

  1. Slide 1: Investor Presentation August 2026

    Investor Presentation August 2026 PETV (OTCQX)

  2. Slide 2: Forward-Looking Statements

    Forward-Looking Statements PETYIVO This presentation and the accompanying oral commentary contains forward-looking statements within the meaning of the federal securities laws, which statements are subject to substantial risks and uncertainties that could cause actual results to differ materially fr

  3. Slide 3: PetVivo - Subsidiaries Org Chart

    PetVivo - SubsidiariesOrgChart @S)PETYIVO PetVivo Holdings, Inc. (PETV) 31© PetVivo: Confidential and Proprietary

  4. Slide 4: Company Highlights

    Company Highlights Market Opportunity +$39.8B US companion animal veterinary care and product sales market with ~ 6% historical CAGR (2020-2024)* Commercial Platform + Next-Generation Product Pipel Spryng®, with OsteoCushion® Technology, is a veterinary device that promotes the restoration of joint

  5. Slide 5: Osteoarthritis (OA) Opportunity

    Osteoarthritis (OA) Opportunity $39.8B Veterinary Care and Product Sales Market Osteoarthritis: Current solutions treat a common affliction symptoms, but do not of the joints manage the cause e Affects approximately 34 million ¢ Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) adult dogs and 1 million

  6. Slide 6: Viscosupplementation

    Viscosupplementation A strong hydrated biomaterial that facilitates enhanced Lubrication and joint-cushioning properties. & Micro-scaffolds Over time, micro-scaffolds adhere to and integrate with the existing synovial membrane. Collagen-Elastin Microparticles Porous, spongy particles absorb and rele

  7. Slide 7: An Optimal OA Solution: Spryng with OsteoCushion Technology

    An Optimal OA Solution: Spryng® with OsteoCushion® Technology Spryng provides a biocompatible lubricious and viscoelastic biomaterial, which promotes the restoration of joint mechanics to improve joint function o Similar components/function found in natural cartilage (i.e. collagen, elastin and hepa

  8. Slide 8: Spryng with OsteoCushion Technology

    Spryng® with OsteoCushion® Technology e Spryng is a unique new medical device addressing the root cause of the affliction, not just the symptoms e Purified natural components self-assemble to form an insoluble, hydrated matrix e Protein source bovine tissues (i.e. medical grade collagen and elastin)

  9. Slide 9: Spryng Mechanism of Action

    Spryng® Mechanism of Action e Ananimal suffering from osteoarthritis generally exhibits damaged and/or lost cartilage thereby creating bone on bone contact that results in an increase of joint inflammation, pain, and further loss of cartilage e Spryng reinforces synovial membrane function, without p

  10. Slide 10: Spryng Canine Success: Koda

    Sean or click to read Koda’s story Spryng® Canine Success: Koda Condition Treatment 4-year-old FS Labrador Retriever e Koda developed a persistent front limb limp following falls in July and September 2023. e Koda’s rehabilitation team recommended Spryng as an option to help address her ongoing elbo

  11. Slide 11: Spryng Equine Success: Red

    Scan or click to read Red’s story Spryng® Equine Success: R History reatmen Results! 26-year-old Quarter Horse e Redrema | pa and e Day 1: That evening, gelding n Red was observed S y trotting to greet his Red was diagnosed with O gt ora owner. severe ringbone and bone- ifferent appr Day 3: Red’ bil

  12. Slide 12: Spryng Canine Success: Pratchett

    Spryng® Canine Success: Pratchett Scan or click to read Pratchett's story Condition Treatment 7-year-old MN Smoke Tabby Shorthair Pratchett developed right hind limb lameness and pelvic discomfort, eventually becoming unable to jump onto the bed or couch. Examination revealed right stifle instabilit

  13. Slide 13: Spryng Competitive Distinctions

    Spryng® Competitive Distinctions @ Outcomes address affliction/not just symptoms e Current treatments rely on biologic activity to treat symptoms; Spryng provides structural components to address affliction Price/Cost advantage Derived from all natural materials Ease of application Vet clinic exclus

  14. Slide 14: Spryng Product Comparison

    Spryng® Product C Features Librela Solensia Adequan HA/Legend Injections per Year 12 16-18 NIA Benefits Last up to 12 Months or More Bioscaffold From Naturally-Derived Components No Synthetic or Radioactive Material Research Supports Joints Health Benefits No Drug Interactions & No Systemic Effects

  15. Slide 15: Spryng Tolerance Studies

    Spryng® Tolerance Studies Canine Tolerance Purpose: Assess tolerance of Spryng® administration in dogs. Design: 20 healthy dogs received intra-articular injection with saline or Spryng@ in contralateral shoulder, hip, elbow, and stifle joints in a randomized sequence. Two-week washout period transpi

  16. Slide 16: Spryng Clinical Studies

    Spryng® Clinical Studies CanineHipOA CASE ETHOS Purpose: Study the effects of Collagen-Elastin Hydrogel Microparticles (Spryng) on pain & function secondary to hip osteoarthritis in dogs. Investigators: Colorado Animal Specialty & Emergency with Ethos Veterinary Health Design: Using Simon's Two-Stag

  17. Slide 17: Spryng Peer-Reviewed Studies

    Spryng® Peer-Reviewed Studies Equine Joint Inflammation Purpose: Evaluate whether Collagen-Elastin Hydrogel Microparticles (CEHM) affect inflammatory responses in equine cartilage and synovial membrane exposed to inflammatory cytokines. Investigators: Cornell University College of Veterinary Medicin

  18. Slide 18: New Spryng Clinical Trials

    New Spryng® Clinical Trials Underway or Recently Completed, Awaiting Publication Canine Study at Colorado State University Principal investigators: Felix Duerr, DVM, MS, Dr. med. vet., CCRT, DACVS-SA, DECVS, DACVSSMR Pilot study design: Pilot study evaluating intra-articular injection of a hydrophil

  19. Slide 19: Functional Biomaterials Platform (CEHM + Piezoelectric Fibers)

    Functional Biomaterials Platform (CEHM + Pieoelectric Fibers) Two Complementary Technologies. One Responsive Intra-Articular Platform. @ Cell-Free & Drug-Free Innovation: Combines PetVivo's proprietary collagen-elastin hydrogel microparticle (CEHM) technology with embedded piezoelectric nanofibers t

  20. Slide 20: Potential Applications for Functional Biomaterials in Veterinary Medicine

    Potential Applications for Functional Biomaterials in Veterinary Medicine Respiratory and Airway Wound Healing Post Surgical Healing Ophthalmic Uses e Corneal Ulceration e Keratoconjunctivitis Sicca e Descemetocele Dental and Oral Surgical Procedures Musculoskeletal Disease/Injury © Osteoarthritis e

  21. Slide 21: State-of-the-Art Production Facilities

    State-of-the-Art Production Facilities e Spryng® product is manufactured in PetVivo's ISO certified cleanrooms (ISO 8 to ISO 7 to ISO 5 e Initial batch sizes of approx. 500 syringes; planning to increase to batches of 5,000+ syringes per month. e Current production facility annual capacity is approx

  22. Slide 22: Comprehensive IP Portfolio

    Comprehensive IP Portfolio e 10 US and Foreign Issued Patents and 2 additional pending Broad Claim Language - “Comprising” Transitions 6 Detailed Proprietary Trade Secrets e Our Patents & Trade Secrets Protect: Protein & Carbohydrate Based Thermoplastics Biomaterials of Many Compositions Medical, Dr

  23. Slide 23: Market Overview

    Sources: American Pet Products Assoc.; North M ar ket Ove ‘Vv i ew American Pet Health Insurance Association, American Horse Council, LendEDU Companion Animal/Veterinarian * Agricultural and professional equine markets not included e US Pet Spend increased from $152B in 2024 to $157B in 2025 e Veter

  24. Slide 24: Animal Product Pipeline

    Animal Product Pipeline FDA clearance not required VD-01 VD-02 VD-03 VD-04 VD-05 VD-06 VD-07 VD-08 Osteoarthritis Osteoarthritis Osteoarthritis Ocular Care Osteoarthritis Wound Care Respiratory Indications babel aia * Canine, Equine, Feline Mucoadhesive Devices 24 1© PetVivo: Confidential and Propri

  25. Slide 25: Human Product Pipeline

    H uman Prod uct Pipel ine FDA Review or Clearance Required for Commercialization of Human Medical Devices FDA clearance required HD-01 Osteoarthritis Human (Spryng@) TBD HD-02 Osteoarthritis Human (Revivion™) = TBD Human nib» Coutanicare (Spryng@/Revivion™) » = Human Bey | Mb puiedieate (Spryng@/Rev

  26. Slide 26: Distribution Partners

    Distribution Partners MWI Animal Heal cencora MWI Animal Health MWI - PetVivo Distribution Services Agreement Terms: e Non-exclusive distribution agreement with ongoing annual renewal option until terminated by either party MWI Overview: e@ One of largest distributors of veterinary products in the w

  27. Slide 27: Distribution Partners Cont.

    Distribution Partners Cont. Patterson Veterinary — PetVivo Distribution Patterson Veterinary Services Agreement Terms: Non-exclusive distribution agreement with ongoing annual renewal option until terminated by either party Patterson Veterinary Overview: One of the largest distributors serving compa

  28. Slide 28: Wholesale Partners

    Wholesale Partners Vedco — Wholesaler Engagement: e Wholesaler relationship to purchase product from PetVivo and sell it to national distributors for subsequent sale to U.S. vets e Designated wholesaler for PetVivo's veterinary medical device, Spryng® with OsteoCusion® Technology Vedco Overview: e V

  29. Slide 29: Digital Landia, LLC (Agentic Pet)

    Digital Landia, LLC (“Agentic Pet”) Artificial Intelligence Exclusive White Label License Relationship: Exclusive white label license agreement between PetVivo and Digital Landia for the AgenticPet™ Al B2B platform. PetVivo holds exclusive commercialization and deployment rights in veterinary market

  30. Slide 30: Digital Landia, LLC (Agentic Pet)

    Digital Landia, LLC (“Agentic Pet”) Artificial Intelligence Current Development Status and Third-Party Validation e Core multi-agent architecture completed and operating in controlled beta environments. e Secure API integrations and modular deployment framework finalized for B2B partners. e Ongoing

  31. Slide 31: PetVivo Strategic Partners

    PetVivo Strategic Partners PiezoBioMembrane, Inc. (“PBM”) and Veterinary Growth Partners (“VGP”)

  32. Slide 32: Management Team Introduction

    Management Team Introduction Deep Bench of Industry Veterans with Decades of Experience . » ) Bryan Monninger Josh Wilhelm VP of Operations & RED John Lai Garry Lowenthal John F. Dolan CEO, President & Director CFO General Counsel VP of Sales & Distributor Relations = ArRAusT Novus €p 2A HEALTH pwe

  33. Slide 33: Strong Independent Board of Directors and Advisors

    Strong Independent Board of Directors and Advisors @ 8 8 9 Advisors Dr. Tracy Turner, DVM, MS, Dipl. ACVS, Dipl. ACSMR, Amer. Academy Thermology, AAEP Board Dr. Sherman Cannap, DVM, MS, CCRT, DACVS-SA, DACVSMER, Cannap Sports Medicine, Orthobiologic Innovations Dr. Debra Cannap, DVM, CCRT, CVA, DACV

  34. Slide 34: Growth Drivers

    Growth Drivers Sales Growth & Expansion e US Direct Veterinary Sales Force e 100% US veterinary market coverage via established distributor network. e International expansion; UK/MX (2025) CA (Q2 2026); EU expected CY2026. e Momentum and growth in clinic adoption and use cases delivering ~ 17% incre

  35. Slide 35: Company Highlights

    Company Highlights Market Opportunity +$39.8B US companion animal veterinary care and product sales market with ~ 6% historical CAGR (2020-2024)* Spryng®, with OsteoCushion® Technology, is a veterinary device that promotes the restoration of joint mechanics for the management of lameness and other j

  36. Slide 36: John Lai, Chief Executive Officer

    John Lai Chief Executive Officer jlai@petvivo.com (952) 405-6216 Spryng® with OsteoCushion® Technology is exclusively sold and distributed by PetVivo Animal Health. Veterinary Use Only - Federal law restricts this device to use by or on the order of a licensed veterinarian. 844-Pet-Vivo (844-738-848

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