Wide Open Agriculture Ltd. · ASX:WOA
Wide Open Agriculture — Technical Presentation (March 2025)
26 slides from Wide Open Agriculture's technical presentation, Mar 24, 2025
Slide 1: Wide Open Agriculture Releases Presentation on the Health Benefits of Lupin Protein
ASX Announcement 24 March 2025 WIDE OPEN AGRICULTURE RELEASES PRESENTATION ON THE HEALTH BENEFITS OF LUPIN PROTEIN Wide Open Agriculture Ltd (ASX:WOA) (“WOA or “the Company”) has today announced the release of a new presenta on outlining the significant health benefits of lupin protein across a broad
Slide 2: About Wide Open Agriculture Ltd
- May assist in managing diabetes - May delay the development of age related macular degenera on - Aid muscle recovery and repair, and muscle growth - May offer fer lity and pregnancy benefits - Posi vely impacts the gut biome - May assist in figh ng breast cancer. The relevant scien fic studies for the
Slide 3: Forward Looking Statements
statements depending on a variety of factors. The past performance of WOA is no guarantee of future performance. None of WOA's directors, officers, employees, agents or contractors makes any representa on or warranty (either express or implied) as to the accuracy or likelihood of fulfilment of any forw
Slide 4: Appendix 1 Studies: Health Indicator
Appendix 1 Studies: Health Indicator Lupin Evidence Reference constituent Hypotensive activity Lupin Rat feeding Pilvi TK, et al (2006) Lupin protein protein study attenuates the development of hypertension and normalises the vascular function of NaCl-loaded Goto- Kakizaki rats. J Physiol Pharmacol.
Slide 5: Metabolic Syndrome Lupin protein studies
Metabolic Syndrome Lupin Dietary Mirmiran P et al (2017) Dietary L- protein intervention Arginine Intakes and the Risk of study Metabolic Syndrome: A 6-Year Follow- Up in Tehran Lipid and Glucose Study. Prev. Nutr. Food Sci. 2017;22(4):263-270 Plasma lipid lowering Lupin Rat feeding Spielmann et al.
Slide 6: Insulin pathways and cancer treatment studies
steatohepatitis in vivo and modulates the expression of the Fasn, Gys2, and Gsk3b genes. Food Sci Nutr. 2021;9:2549–2560. Insulin pathways Lupin ex vivo and Santana SM et al (2018) Narrow-leafed protein in vitro lupin (Lupinus angustifolius L.) seed β- system conglutins reverse the induced insulin r
Slide 7: Conglutin in vitro studies
myoblast. Nutr Metab Cardio-vasc Dis. 21:197-205 Ƴ -conglutin In vitro study Tapadia M et al (2021) Antidiabetic e ects and mechanisms of action of γ- conglutin from lupin seeds. Journal of Functional Foods 87 (2021) 104786 The future is wide open. Creating ingredients for food and drink products th
Slide 8: Lupin Protein Health Benefits
Lupin Protein Health Benefits Backed by Nature, Powered by Science
Slide 9: Disclaimer
Disclaimer This presentation has been prepared by Wide Open Agriculture Limited (ASX: WOA) (the “Company”). It does not purport to contain all the information that a prospective investor may require in connection with any potential investment in the Company. You should not treat the contents of this
Slide 10: Lupin Health Benefits
LUPIN Company Presentation HEALTH BENEFITS Blood pressure An estimated 1.28 billion adults are believed to have high blood pressure globally (hypertension)2 Lupin consumption has been shown to reduce blood pressure Lupins have been shown to have health benefits across some of the most Heart health C
Slide 11: Essential Amino Acid Profile
Company Presentation Lupins have higher levels of Essential Amino Acids (EAAs) than other key plant proteins Essential Amino Acid Profile ESSENTIAL 40 35 AMINO 30 Total EAA g/100g 25 ACID 20 15 PROFILE 10 5 0 Lupin Oat Soy Pea Almond Whey Milk Essential Amino Acids cannot be produced by the body and
Slide 12: Total Amino Acid Profile
Company Presentation Lupins have the highest Total Amino Acid profiles compared to other key protein sources Amino Acid Profiles TOTAL 120.00 100.00 AMINO 80.00 ACID 60.00 PROFILE 40.00 20.00 - Lupin Oat Soy Pea Almond Whey Milk Threonine * Methionine*+ Cysteine * Tyrosine Phenylalanine+ Lysine * Va
Slide 13: Improved Cardio-Metabolic Health
IMPROVED CARDIO-METABOLIC HEALTH Company Presentation Scientific studies show that consuming lupin protein positively impacts cardio- metabolic health by: LOWERING CHOLESTEROL LOWERING BLOOD PRESSURE IMPROVING BLOOD GLUCOSE CONTROL LOWERS CHOLESTEROL: consuming lupin protein resulted in reduced chol
Slide 14: Lowers Cholesterol
Company Presentation Clinical and biochemical studies have shown evidence of REDUCED Overall Cholesterol LOWERS on consuming lupin protein 2,3,4,5,6,7 CHOLESTEROL Recent studies also reported improved ratio of HDL (good fats) : LDL (bad fats) through activating the LDL receptors in the body.
Slide 15: Lowers Blood Pressure
LOWERS Company Presentation BLOOD PRESSURE Recent studies have shown that including lupin protein in diets can: • Assist with controlling hypertension • Reduce blood systolic pressure 1 Lupin protein is one of the BEST NATURAL SOURCES of Arginine, which is biochemically proven to improve blood vesse
Slide 16: Improved Blood-Sugar Management
IMPROVED Company Presentation BLOOD-SUGAR MANAGEMENT Lupin protein may assist managing diabetes through activating insulin signalling pathways, increasing insulin sensitivity and promoting glucose uptake to help muscle cells absorb glucose and synthesize glycogen 11,16,17,18 A number of acute studie
Slide 17: Muscle Recovery and Repair
MUSCLE Company Presentation RECOVERY AND REPAIR lupin protein is a naturally high source of L-arginine, that supports blood flow during periods of muscular recovery, repair and growth L-Arginine has been shown to mediate nitric oxide production and has strong antioxidant properties. It has therapeut
Slide 18: Muscular Growth
MUSCULAR Company Presentation GROWTH Lupin protein is a good source of lysine, helpful in supporting athletic performance 28 Lupin protein is also high in leucine, which is the primary driving force behind the 27 development of new muscle and overall muscle health
Slide 19: Fertility
FERTILITY Company Presentation Lupin is a rich source of L- arginine, which plays a key role in women’s hemodynamic adaptations during gestation L-arginine may help regulate many metabolic pathways that are vital to reproduction, growth, and health and its deficiency may lead to pregnancy complicati
Slide 20: Macular Degeneration
MACULAR Company Presentation DEGENERATION Lupin protein is a rich source of lutein Lutein can delay the start of, and slows down the development of, the consequences of age-related macular degeneration (AMD) . 21 Lutein does not cure AMD, but it can slow the progression of this disease.
Slide 21: Natural Cytotoxic Agent
Investor Presentation NATURAL CYTOTOXIC AGENT A recent study found lupin protein extracts to be effective at preserving the viability of healthy cells in breast cancer patients, opening up further avenues of research into the disease 20
Slide 22: Next Steps
NEXT STEPS Company Presentation • Work with Universities, Governments and Independent Research Organisations to further explore the health benefits of lupin protein • Work with food companies and consumer organisations to highlight the benefits of lupin in their product development programmes and th
Slide 23: References
References 1. Pilvi TK, et al (2006) Lupin protein attenuates the development of hypertension and normalises the vascular function of NaCl-loaded Goto-Kakizaki rats. J Physiol Pharmacol. 57(2):167-76. 2 Bähr et al.(2013) Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol
Slide 24: References
References 10 Sirtori C et al (2011) Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals. British Journal of Nutrition (2012), 107, 1176–1183. 11 Pavanello C et al (2017) Effects of a lupin protein concentrate on lipids, bl
Slide 25: References
References 19 Deakin University (2023) Satiety/ appetite control lupin protein study funded by Wide Open Agriculture Ltd. 20 Escudero-Feliu J et al (2023) Narrow Leafed Lupin (Lupinus angustifolius L.) β-Conglutin Seed Proteins as a New Natural Cytotoxic Agents against Breast Cancer Cells. Nutrients
Slide 26: Thank You
Thank You Matthew Skinner Chief Executive Officer M: (+61) 0468 303 620 E: matthew.s@wideopenagriculture.com.au
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