Arbutus Announces Three Poster Presentations with Clinical Data from AB-729 and Preclinical Data from AB-101 at AASLD - The Liver Meeting® 2022

Conference Call and Webcast to discuss the new data being presented at AASLD scheduled for 8:45 AM ET, Friday, November 4, 2022

WARMINSTER, Pa., Oct. 31, 2022 (GLOBE NEWSWIRE) -- Arbutus Biopharma Corporation (Nasdaq: ABUS), a clinical-stage biopharmaceutical company leveraging its extensive virology expertise to develop novel therapeutics that target specific viral diseases, today announced that the Company will be presenting three posters with clinical data from its lead clinical compound, AB-729, an RNAi therapeutic, and its preclinical oral PD-L1 inhibitor, AB-101, at The American Association for the Study of Liver Diseases (AASLD) – The Liver Meeting® 2022, taking place from November 4-8, 2022 in Washington, DC.

Poster #1:

Title: Hepatitis B viral control maintained during extended follow up of HBeAg- chronic hepatitis B subjects who discontinued nucleos(t)ide analogue (NA) therapy after completion of AB-729 treatment, and in HBeAg+ subjects still on NA therapy 

Poster Number: 5047

Abstract Number: 38876

Presentation Type: Late-Breaking Poster Presentation

Presentation Time: Monday, November 7: 1:00 – 2:00 PM ET

Authors: Man-Fung Yuen, Jacinta Holmes, Simone I Strasser, Apinya Leerapun, Wattana Sukeepaisarnjaroen, Pisit Tangkijvanich, Varun Sharma, Elina Medvedeva, Emily P Thi, Gastón Picchio, Timothy Eley, Karen D Sims 

Data Summary:   Data is being reported on nine patients who have completed from 16 to 40 weeks of follow-up after discontinuing both AB-729 and NA therapy. No patients met the protocol-defined NA restart criteria. At the last available timepoint, all HBV DNA levels were