Spero Therapeutics, Inc. · NASDAQ:SPRO

Spero Therapeutics, Inc. shareholders

As of Jun 30, 2026, 56 institutions reported holding Spero Therapeutics, Inc., 36.9% of its shares. Largest: GSK plc, Pfizer Inc and Vanguard. New holders, exits, insiders and big stakes, each with its filing.

HolderShares% of Spero Therapeutics, Inc.ChangeFiled
GSK plc9.19M15.8%no changeAug 13, 2026
Pfizer Inc2.36M4.1%no changeAug 13, 2026
Vanguard2.35M4.0%+260KAug 13, 2026
Renaissance Technologies948K1.6%−241KAug 13, 2026
Alphabet Inc.890K1.5%no changeAug 7, 2026
Susquehanna793K1.4%+460KAug 14, 2026
BlackRock594K1.0%+161KAug 7, 2026
Geode Capital566K0.97%+46,407Aug 12, 2026
Raymond James Financial Inc522K0.90%newAug 14, 2026
Two Sigma393K0.68%−492KAug 14, 2026

Spero Therapeutics, Inc. insider trades