| Dianthus Therapeutics, Inc. | 2,739 | US$293K | 5.3% |
| Xenon Pharmaceuticals Inc. | 4,264 | US$267K | 4.9% |
| Praxis Precision Medicines, Inc. | 868 | US$267K | 4.9% |
| Acadia Pharmaceuticals Inc. | 9,949 | US$257K | 4.7% |
| Arrowhead Pharmaceuticals, Inc. | 3,016 | US$255K | 4.7% |
| Alkermes Plc | 5,153 | US$252K | 4.6% |
| Scholar Rock Holding Corporation | 4,979 | US$235K | 4.3% |
| Biogen Inc. | 1,129 | US$229K | 4.2% |
| Neurocrine Biosciences, Inc. | 1,345 | US$224K | 4.1% |
| Ptc Therapeutics, Inc. | 3,109 | US$211K | 3.9% |
| Axsome Therapeutics, Inc. | 949 | US$207K | 3.8% |
| Denali Therapeutics Inc. | 8,750 | US$201K | 3.7% |
| Dyne Therapeutics, Inc. | 7,764 | US$195K | 3.6% |
| Edgewise Therapeutics, Inc. | 4,615 | US$177K | 3.2% |
| Supernus Pharmaceuticals, Inc. | 3,202 | US$143K | 2.6% |
| Axogen, Inc. | 3,041 | US$128K | 2.3% |
| Sk Biopharmaceuticals Co., Ltd. | 2,295 | US$126K | 2.3% |
| H. Lundbeck A/s Class A | 15,754 | US$101K | 1.8% |
| Biohaven Ltd. | 7,377 | US$99,590 | 1.8% |
| Sarepta Therapeutics, Inc. | 5,954 | US$88,476 | 1.6% |
| Bioarctic Ab Class B | 2,506 | US$85,563 | 1.6% |
| Taysha Gene Therapies, Inc. | 13,999 | US$82,034 | 1.5% |
| Neuren Pharmaceuticals Limited | 6,435 | US$81,113 | 1.5% |
| Idorsia Ltd. | 10,423 | US$78,965 | 1.4% |
| Rapport Therapeutics, Inc. | 1,673 | US$68,560 | 1.2% |
| Integra Lifesciences Holdings Corporation | 3,915 | US$65,185 | 1.2% |
| Alto Neuroscience, Inc. | 1,846 | US$49,971 | 0.91% |
| Lb Pharmaceuticals Inc | 1,221 | US$48,938 | 0.89% |
| Dynavox Group Ab | 5,818 | US$43,886 | 0.80% |
| Annexon, Inc. | 8,380 | US$42,696 | 0.78% |
| Medincell Sa | 1,372 | US$41,256 | 0.75% |
| Solid Biosciences Inc. | 4,599 | US$37,068 | 0.68% |
| Bright Minds Biosciences Inc. | 445 | US$32,601 | 0.59% |
| Relmada Therapeutics, Inc. | 5,416 | US$28,759 | 0.52% |
| Design Therapeutics, Inc. | 2,215 | US$26,979 | 0.49% |
| Regenxbio Inc. | 2,749 | US$26,638 | 0.49% |
| Oncolys Biopharma, Inc. | 1,600 | US$26,307 | 0.48% |
| Ceribell, Inc. | 1,447 | US$25,597 | 0.47% |
| Neurogene Inc. | 740 | US$24,339 | 0.44% |
| Clearpoint Neuro Inc. | 1,572 | US$23,486 | 0.43% |
| Benitec Biopharma Inc. | 1,981 | US$23,198 | 0.42% |
| Prothena Corporation Plc | 2,759 | US$22,403 | 0.41% |
| Ovid Therapeutics Inc. | 9,777 | US$21,705 | 0.40% |
| Microport Neuroscientific Corporation | 19,000 | US$21,657 | 0.39% |
| Neuropace, Inc. | 1,543 | US$19,889 | 0.36% |
| Sanbio Co., Ltd. | 3,400 | US$19,555 | 0.36% |
| Zylox-tonbridge Medical Technology Co., Ltd. Class H | 8,000 | US$19,417 | 0.35% |
| Vanda Pharmaceuticals Inc. | 3,342 | US$17,044 | 0.31% |
| Newron Pharmaceuticals S.p.a. | 1,060 | US$15,362 | 0.28% |
| Anavex Life Sciences Corp. | 5,343 | US$14,693 | 0.27% |
| Peijia Medical Ltd. | 28,000 | US$14,313 | 0.26% |
| Santhera Pharmaceuticals Holding Ag | 771 | US$13,512 | 0.25% |
| Inhibikase Therapeutics, Inc. | 5,679 | US$12,380 | 0.23% |
| Capricor Therapeutics, Inc. | 3,077 | US$11,846 | 0.22% |
| Larimar Therapeutics, Inc. | 3,008 | US$11,491 | 0.21% |
| Tonix Pharmaceuticals Holding Corp. | 953 | US$9,540 | 0.17% |
| Voyager Therapeutics, Inc. | 3,080 | US$9,332 | 0.17% |
| Entrada Therapeutics, Inc. | 1,328 | US$9,017 | 0.16% |
| Ac Immune Sa | 3,783 | US$8,285 | 0.15% |
| Acumen Pharmaceuticals, Inc. | 3,768 | US$8,101 | 0.15% |
| Alector, Inc. | 4,762 | US$7,191 | 0.13% |
| Neumora Therapeutics, Inc. | 4,388 | US$7,065 | 0.13% |
| Myung In Pharm Co., Ltd. | 212 | US$6,241 | 0.11% |
| Pepgen Inc. | 3,476 | US$6,118 | 0.11% |
| Maplight Therapeutics, Inc. | 445 | US$5,794 | 0.11% |
| Cognition Therapeutics, Inc. | 4,543 | US$4,041 | 0.07% |
| Filana Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Sangamo Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Gain Therapeutics, Inc. | 0 | US$0 | 0.00% |
| Catalyst Pharmaceuticals, Inc. | 0 | US$0 | 0.00% |
| Yibin City Commercial Bank Co., Ltd. Class H | 0 | US$0 | 0.00% |