Slide 1: Halberd Corporation stock is traded on the OTC under the symbol HALB
Halberd Corporation stock is traded on the OTC under the symbol “HALB” Visit us at www.halberdcorporation.com © 2022 Halberd Corporation 1
Slide 2: Halberd Corporation Biologics Group
Halberd Corporation Biologics Group Extracorporeal Treatment • PTSD/Suicide Ideation • Neurodegenerative diseases • Bacterial/Viral infections 2 © 2022 Halberd Corporation
Slide 3: Traumatic Brain Injury in the News
Traumatic Brain Injury in the News .com Purdue University – “A two-year study of high school football players suggests that concussions are likely caused by many hits over time and not from a single blow to the head, as commonly believed.” -- Science Daily, Feb. 2, 2012 3 © 2022 Halberd Corporation
Slide 4: Detection – Today: Inexact & Relies on Cognitive Testing
Detection – Today: Inexact & Relies on Cognitive Testing Standard detection test: ImPACT (Immediate Post-Concussion Assessment and Cognitive Testing) “They’ve done incredible marketing, and they’ve managed to establish this test as the standard of care with no evidence that it has any benefit.” -- R
Slide 5: Two-Year Study by Purdue University
Two-Year Study by Purdue University • High School Football Team Studied (21 players first year; 24 players second year; 16 players both yrs.) • Players received from 200 to nearly 1,900 hits to the head in a single season, with two players exceeding 1,800 hits. • Helmet-sensor data indicated impact
Slide 6: It’s All About Physics!
It’s All About Physics! Kinetic Energy = ½ x Mass x Velocity2 Football Player NASCAR Driver • Mass of Brain = 3 lbs. • Mass of Brain = 3 lbs. • Closing Speed: 20 MPH • Closing Speed: 200MPH Runs into wall Runs into wall • Kinetic Energy • Kinetic Energy KEF = ½ x Mass x (20)2 KEN = ½ x Mass x (20 x
Slide 7: The Major Issue
The Major Issue In closed head injury, surgery does not correct the problem. www.traumaticbraininjury.com Concussions are caused principally by sudden changes in momentum. No change in helmet technology can fix the underlying problem. "It's the egg-yolk-inside-the-shell analogy. Making the shell str
Slide 8: Treatment
Treatment • Today’s treatments prescribe only rest to allow the body to heal itself, in time. • There is NO Proactive Treatment for TBI Until Now!!! 8 © 2022 Halberd Corporation
Slide 9: HALB Technology Basis … The Felder Doctrine
HALB Technology Basis … The Felder Doctrine™ “Physical removal of the pathophysiologic basis of the disease.”TM 9 © 2022 Halberd Corporation
Slide 10: Halberd Technology
Halberd Technology Brain injury induces increased production of adverse proteins/molecular compounds by brain resident cells. Halberd is taking a dual path approach: 1. Prevention of neurodegeneration through immediate post-trauma nasal spray treatment. 2. Treatment of neurodegenerative diseases lon
Slide 11: Halberd Technology: Prevention
Halberd Technology Prevention: Halberd is developing a revolutionary nasal spray treatment for field use which reduces the negative effects of head trauma. This easy-to-use nasal spray, when administered within the first hours after a traumatic brain injury can: • Reduce or eliminate the production
Slide 12: Halberd Technology: Neurodegenerative Disease Treatment
Halberd Technology Neurodegenerative Disease Treatment: Brain injury: • Induces increased production of adverse proteins/molecular compounds by brain resident cells. • Leads to various neurodegenerative diseases – PTSD Alzheimer’s Disease – Suicidal ideation – Other debilitating diseases. Halberd’s
Slide 13: Halberd Technology
Halberd Technology Brain injury induces increased production of adverse proteins/molecular compounds by brain resident cells. Using HALB’s proprietary technology, we have been able to remove these adverse molecular compounds from Cerebrospinal Fluid using designer antibodies and metallic nanoparticl
Slide 14: Halberd Has Demonstrated Elimination of Numerous Neurological Pathogens
Halberd Has Demonstrated Elimination of Numerous Neurological Pathogens 14 © 2022 Halberd Corporation
Slide 15: Sequential Dialysis
Sequential Dialysis Sequential-Dialysis Technique is a methodology for the removal of molecules which are harmful and responsible for causing diseases. – Fluids are temporarily removed from the body using a typical dialysis method. – Halberd’s designer antibodies are added to the fluid outside the b
Slide 16: Sequential Dialysis Model
Sequential Dialysis Model Mechanical Filtered Blood/CSF Laser returned to the patient Patented method for the Filter removal of specific and unique molecules utilizing antibody antigens as a target attraction Antibody-Antigen Mixing Chamber Patient Smart Sensor Mixing Chamber HALB designer antibody
Slide 17: Halberd’s Target Antigen Removal Process Using Chemical Bonding
Halberd’s Target Antigen Removal Process Using Chemical Bonding Cartridge contains antibodies bonded to the inner surfaces to attract and retain target antigens. 17 © 2022 Halberd Corporation
Slide 18: Goals and Objectives for Traumatic Brain Injury/Concussions
Goals and Objectives for Traumatic Brain Injury/Concussions Use Sequential Dialysis Following a traumatic brain injury to remove the excitatory neurotransmitters which cause plaque and tangles leading to apoptosis (cell death) in the brain. 18 © 2022 Halberd Corporation
Slide 19: U.S. Patent: Extracorporeal Treatment
U.S. Patent: Extracorporeal Treatment 19 © 2022 Halberd Corporation
Slide 20: U.S. Patent: Emissive Energy Extracorporeal Treatment
U.S. Patent: Emissive Energy Extracorporeal Treatment 20 © 2022 Halberd Corporation
Slide 21: U.S. Provisional Patent Application: Chemical Bonding
U. S. Provisional Patent Application: Chemical Bonding 21 © 2022 Halberd Corporation
Slide 22: Antibody/Antigen Therapy
Antibody/Antigen Therapy Extracorporeal Sequential Dialysis Method (ESDM) – Patented Treatment Process • US Patents No. 9,216,386 and No. 8,758,287 – Elimination of Disease Antigens – Applicable To Many Blood-/CSF-borne Diseases • PTSD/TBI/CTE Cancer • Menningitis • Alzheimer’s • Cockayne Syndrome •
Slide 23: HALB Extracorporeal Advantages
HALB Extracorporeal Advantages • Patented Process • Can Be used in Conjunction With Laser or Radiofrequency eradication or Chemical Bonding/Filtration Methods • Laser eradication uses designer antibodies conjoined to metallic nanoparticles which attach to the target antigen and are locally heated by
Slide 24: Animal Testing
Animal Testing • Discussions initiated with Mississippi State University – Non-Disclosure Agreement signed – Discussions on type and size of animal testing • Engaged FDA process consulting firm to plan and guide testing to expedite FDA review and certification process. 24 © 2022 Halberd Corporation
Slide 25: Blood-Borne Disease Treatment
Blood-Borne Disease Treatment • Patented Procedure to treat blood extra- corporeally with antibody conjugated metallic nanoparticles to eliminate through exposure to high energy emissive radiation (e.g., laser), or removal through chemical bonding filtration. • Initial applications envisioned for tr
Slide 26: Technology Partners - Biologics
Technology Partners - Biologics • Arizona State University • Youngstown State University • Mississippi State University • mdi Consultants, Inc. (FDA certification specialists) 26 © 2022 Halberd Corporation
Slide 27: Summary
Summary HALB’s Sequential Dialysis Methodology is a novel approach that eliminates the molecules and proteins from the body that cause disease. By having this process occur in a device outside the body, targeting the cause rather than the effect of a disease, side effects are severely reduced, if no
Slide 28: A World Leader in New Biomedical Technology Research & Development
A World Leader in New Biomedical Technology Research & Development William A. Hartman Chairman, President & CEO P.O. Box 25 Jackson Center, PA 16133 Phone: 814-786-8849 Skype name: w.a.hartman Email: w.hartman@halberdcorporation.com Visit us at www.halberdcorporation.com 28 © 2022 Halberd Corporatio