Slide 1: Intimation regarding Analysts/Institutional Investors meet
Biocon Limited No: 2017/SEC/JUN/058 20th KM Hosur Road Electronics City Date: June 23, 2017 Bangalore 560 100, India T 91 80 2808 2808 National Stock Exchange of India Limited BSE Limited F paleo 2852 3423 “Exchange Plaza”, 5th Floor, Phiroze Jeejeebhoy Towers, MSE SEE Ste As Plot No. C/1, G Block,
Slide 2: Investor Presentation June 2017
Investor Presentation June 2017 BSE: 532523 │ NSE: BIOCON │ REUTERS: BION.NS │ BLOOMBERG: BIOS IN │ WWW.BIOCON.COM
Slide 3: Safe Harbor
Safe Harbor Certain statements in this release concerning our future growth prospects are forward-looking statements, which are subject to a number of risks, uncertainties and assumptions that could cause actual results to differ materially from those contemplated in such forward-looking statements.
Slide 4: Agenda
Agenda Biocon: Who are we? Highlights • Business Highlights • Financial Highlights Business Segments • Small Molecules • Biosimilars • Branded Formulations • Novel Molecules • Research Services - Syngene Five Year Financial Summary Outlook 3
Slide 5: Who are we?
BS Biocon C: o = o — o ° £ S
Slide 6: Biocon: Asia's Leading Biopharma Company
Biocon: Asia’s Leading Biopharma Company Our Vision To enhance global healthcare through innovative and affordable biopharmaceuticals for patients, partners and healthcare systems across the globe 5
Slide 7: The Biocon Journey: A continuous evolution
The Biocon Journey: A continuous evolution Transforming into a Building the Base Business Poised for global impact with Biopharma company and expertise in biologics Biosimilar insulins & Antibodies Revenues: ₹5,490 Million Revenue: ₹ 11,940 Million Target US$1bn in sales by FY19 People: 700+ People:
Slide 8: Evolution of Key Innovations: Making a Difference
Evolution of Key Innovations: Making a Difference 1979 - First Indian company to manufacture and export enzymes to US and Europe 2001 - First Indian company to be approved by US FDA for the manufacture of lovastatin from solid state fermentation 2004 - First company worldwide to commercialize generi
Slide 9: Highlights – FY17 and recent
Highlights – FY17 and recent Marketing Authorization Application for proposed biosimilars of Pegfilgrastim, Trastuzumab and Insulin Glargine accepted for review by the European Medicines Agency. Proposed biosimilars of Trastuzumab and Pegfilgrastim accepted for review by USFDA. Oncology Advisory Com
Slide 10: Highlights – FY17 and recent (cont.)
Highlights – FY17 and recent (cont.) Received FDA approval for Rosuvasatin Calcium, first ANDA approval for Biocon. Biocon Ranked Among Global Top Ten Biotech Employers; the only Asian Company to Feature in 2016 Rankings released by Science Career magazine. The Board of Directors had recommended for
Slide 11: Financial Highlights – Q4 & FY17
Financial Highlights* – Q4 & FY17 All Figures in ₹ Million except % Particulars Q4 FY17 Q4 FY16 Growth FY17 FY16 Growth Revenue 9,743 9,727 0% 40,787 34,602 18% EBITDA 2,307 2,206 5% 11,366 8,470 34% Net Profit# 1,353 769 76% 6,199 4,021 54% R&D Expenses in P&L 652 996 -35% 2,662 2,742 -3% Gross R&D
Slide 12: Segmental Sales – Q4 & FY17
Segmental Sales* – Q4 & FY17 All Figures in ₹ Million except % Particulars Q4 FY17 Q4 FY16 Growth FY17 FY16 Growth Biocon 6,528 6,298 4% 27,381 22,773 20% - Small Molecules 3,869 3,950 -2% 15,868 13,870 14% - Biologics 1,194 1,193 0% 4,573 3,415 34% - Branded Formulations 1,310 1,052 25% 5,491 4,411
Slide 13: Business Segments
Bs Biocon Business Segments
Slide 14: Growth Verticals: Aligned with Shifting Paradigms
Growth Verticals: Aligned with Shifting Paradigms 1. (a) APIs and (b) Generic Formulations Small Molecules 5. Contract Research & 2. Exports of Insulins, Manufacturing MAbs & Other Biologics Research Biosimilars Services (Biologics & (Syngene) g. Insulins) Growth Verticals Novel Branded 4. Unlock Va
Slide 15: Small Molecule APIs
Small Molecule APIs Product Portfolio which leverages our core fermentation capabilities and have a high degree of complexity. Early mover in niche products at commercial scale. One of the largest producers of various fermentation based statins and immunosuppressant API in India and across the globe
Slide 16: Small Molecule Generic Formulations
Small Molecule Generic Formulations Vertically integrated business model with a nascent pipeline. Target to file ~10-15 dossiers in the next few years. Pipeline includes solid oral & parenteral products in both potent & non-potent categories of compounds. Focus therapeutic segments – Metabolics, Onc
Slide 17: Biosimilars
Biosimilars Marketing Authorization Application for proposed biosimilars of Pegfilgrastim, Trastuzumab and Insulin Glargine accepted and under review by the European Medicines Agency. Proposed biosimilars of Trastuzumab and Pegfilgrastim under review by USFDA. Generic Insulin Glargine in the US and
Slide 18: Biosimilars: Growth through partnership
Biosimilars: Growth through partnership BIOCON MYLAN • Global-scale, complex biologics • Strength in Regulatory/ filings manufacturing capabilities strategy • Facilities accredited by • Strong commercialization international regulatory agencies capability in US and EU. • Decade-long experience & • M
Slide 19: Global Biosimilars Pipeline – US$61 bn opportunity
Global Biosimilars Pipeline – US$61 bn opportunity Market Size* Molecule Type Status (US$ bn) Rh Insulin Regular Acting Insulin Pre-clinical (US), Marketed in EM 3.2 INSULINS Filed in EU, Australia & Canada. US Glargine Long Acting Insulin filing in H1 FY18. Marketed in Japan 6.4 (since Jul-16) & EM
Slide 20: Biosimilar Pipeline: Biocon well placed in the competitive landscape
Biosimilar Pipeline: Biocon well placed in the competitive landscape Molecule Biosimilar Development Pipeline@ Pre-Clinical Phase I Phase III/Filed Approved/ Marketed Pegfilgrastim Pfizer Dr. Reddy’s Biocon-EMA, FDA; Apotex - FDA, EMA; Coherus - EMA; Sandoz, Cinfa trastuzumab Oncobiologics, Meiji Se
Slide 21: Biosimilars Manufacturing: Building Global Scale
Biosimilars Manufacturing: Building Global Scale Biocon Malaysia: Asia’s largest integrated insulins manufacturing facility Biocon’s First Manufacturing expansion overseas in Iskandar, Johor. Investment of over US$250mn in the first phase. Commercial supplies initiated with OTA award by Ministry of
Slide 22: Branded Formulations
Branded Formulations A Specialty Business with regional ambitions, currently in India and UAE. Strategy focused around biologics and differentiated products as anchor brands. The UAE business sells Branded generics and in-licensed Branded products. India business organized into 5 divisions aro
Slide 23: Novel Molecules - Pipeline & Therapeutic Area Focus
Novel Molecules - Pipeline & Therapeutic Area Focus Insulin Tregopil * Phase II Ready DIABETES T1D/ T2D First-in-Class Oral, Prandial Insulin Itolizumab* Phase I Ongoing Novel, humanized CD6 Antibody BVX-20# IND Ready Novel, humanized CD20 Antibody INFLAMMATION QPI-1007$ Phase III Initiated SiRNA fo
Slide 24: Novel Molecules – Progressing to key milestones
Novel Molecules – Progressing to key milestones Asset Details Tregopil USP: Oral, Ultra Rapid-Acting Phase II Ready Post- prandial glycemic control; Liver specific- portal delivery, Weight neutral Safety & tolerability established in Phase 1 studies in US – DDI, Food Effect, PK/PD Data available
Slide 25: Syngene (Research Services Business)
Syngene (Research Services Business) Global High Growth CRO Company Established in 1994, as India’s first Contract Research Organization – 22+ years of unparalleled experience in novel molecule discovery and development services One of the leading India-based contract research organizations (CRO) In
Slide 26: Five Year Financials & Outlook
Five Year Financials & Outlook 25
Slide 27: Financial Performance Summary (FY12-16)
Financial Performance Summary (FY12-16)# All Figures in ₹ Million except EPS Business Segment FY12 FY13 FY14 FY15 FY16 Biopharmaceuticals 16,764 18,705 21,382 22,367 23,908 - Biopharma 14,170 15,231 17,468 18,071 19,534 - Branded Formulations 2,594 3,474 3,914 4,296 4,374 Contract Research 4,101 5,5
Slide 28: Aspiring for $1 Billion in Revenues by FY19
Aspiring for $1 Billion in Revenues by FY19 Key Focus Areas o Small Molecules & Generic Formulations - Improved product mix incl. ANDAs o Biosimilars - Meaningful near term growth to be driven 25% by emerging markets, ramp up post developed market entry 30% o Branded Formulations –Strategy focused a
Slide 29: Appendix
BS Biocon 2s os < ® 2. 2. <x
Slide 30: Business Holdings Structure
Business Holdings Structure Biocon Limited, India Small Molecules & ANDA Biocon Pharma, India (100%) Branded Formulations Biocon Pharma, US (100%) Biocon FZ LLC (100%)/ NeoBiocon, UAE (49%) Biocon Biologics, UK Biocon SA, Switzerland Syngene, India (100%) (100%) (73.54%)* Biocon Sdn Bhd, Biocon MAb
Slide 31: For further information, please visit www.biocon.com
For further information, please visit www.biocon.com Investor Relations contact: Saurabh Paliwal Tel : +91 80 6775 2040 Email: saurabh.paliwal@biocon.com