Adaptive Biotechnologies Corporation · NASDAQ:ADPT

Adaptive Biotechnologies — Q3 2021 Earnings Presentation

10 slides from Adaptive Biotechnologies's earnings presentation, 2021

  1. Slide 1: Third Quarter 2021 Earnings Conference Call

    Third Quarter 2021 Earnings Conference Call

  2. Slide 2: Safe Harbor

    Safe Harbor This presentation has been prepared by Adaptive Biotechnologies Corporation (“we,” “us,” “our,” “Adaptive” or the “Company”) and is made for informational purposes only. The information set forth herein does not purport to be complete or to contain all relevant information. Statements co

  3. Slide 3: Q3 2021 Key Highlights

    Q3 2021 Key Highlights ✓ .ClonoSEQ / MRD Pharma: ◼ Launched IGHV status for CLL patients ◼ Recognized regulatory milestone in MRD from pharma partner ✓ . T-Detect / immunoSEQ T-MAP: ◼ Obtained Medicare coverage for T-Detect COVID for immunocompromised patients ◼ Correlate of protection studies using

  4. Slide 4: clonoSEQ brand: Increase in clinical adoption and pharma partnerships

    clonoSEQ brand: Increase in clinical adoption and pharma partnerships clonoSEQ Clinical Testing MRD Pharma Portfolio ◼ Q3’21 test delivered volume +47% vs P/Y; +8% vs P/Q ◼ Significant value driver to the overall MRD franchise ❑ ~260 ordering accounts; ~1,020 ordering HCPs in Q3 ◼ Structured to cont

  5. Slide 5: T-Detect COVID focus; leveraging Coverage and T-MAP pharma partnerships

    T-Detect COVID focus; leveraging Coverage and T-MAP pharma partnerships T-Detect update: Infectious Disease Leveraging Partnerships Widening adoption of immunoSEQ T-MAP COVID / T-Detect COVID COVID with Pharma, Biotech and Research ◼ Medicare coverage for immuno-compromised patients Published data s

  6. Slide 6: Progress on our open-ended growth story in Drug Discovery

    Progress on our open-ended growth story in Drug Discovery Cell Therapy: identify TCRs as Therapeutics ✓ Shared Product: on track to assess efficacy and safety data with GNE to enable a decision by YE to move our lead product into early development ✓ Private Product: on track to process blood from ~6

  7. Slide 7: Q3 2021 Key Financial Highlights

    Q3 2021 Key Financial Highlights 3 Revenues ($M) Operating Expenses ($M) Sequencing $39.5 +50% Development $95.4 +52% $26.3 +96% 22.1 $62.9 11.3 1 2 +16% 15.0 17.4 Q3 2020 Q3 2021 Q3 2020 Q3 2021 1 Includes $2.5M in MRD milestones 3 Excludes amortization of intangible assets 2 Includes $1.5M in MRD

  8. Slide 8: 2021 remaining milestones

    2021 remaining milestones ◼ Embed T-MAP COVID into SARS-CoV-2 vaccine studies ◼ T-Detect IBD: analysis of >5,000 IBD samples ◼ Confirm additional T-Detect signal(s) ◼ FDA decision for clonoSEQ ALL in blood ◼ Shared product: decision to move lead candidate into early development ◼ Private product: pr

  9. Slide 9: Thank You.

    Thank You.

  10. Slide 10: Clinical portfolio and pipeline

    Clinical portfolio and pipeline Diagnostic Signal Clinical FDA FDA Product Plan Discovery Validation Submission Clearance Multiple Myeloma (bone marrow) Monitor MRD: Acute Lymphoblastic Leukemia (bone marrow) Chronic Lymphocytic Leukemia (blood, bone marrow) Non-Hodgkin’s Lymphoma (Subtypes)1 COVID-

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